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English Journal

Association between the APOB XbaI and EcoRI polymorphisms and lipids in Chinese: a meta-analysis.

Gu W1, Zhang M2, Wen S3.
Lipids in health and disease.Lipids Health Dis.2015 Oct 7;14:123. doi: 10.1186/s12944-015-0125-z.
BACKGROUND: No previous meta-analysis was to report the association between the apolipoprotein B (APOB) XbaI and EcoRI polymorphisms and serum lipids in Chinese. We performed the study to investigate their potentially association.METHODS AND RESULTS: Studies in English and Chinese were found via a s
PMID 26446158

Background eliminated signal-on electrochemical aptasensing platform for highly sensitive detection of protein.

Zhang S1, Hu X2, Yang X2, Sun Q2, Xu X2, Liu X2, Shen G2, Lu J2, Shen G3, Yu R3.
Biosensors & bioelectronics.Biosens Bioelectron.2015 Apr 15;66:363-9. doi: 10.1016/j.bios.2014.11.044. Epub 2014 Nov 24.
Using platelet-derived growth factor B chain dimer (PDGF-BB) as the model target, a background current eliminated electrochemical aptameric sensing platform for highly sensitive and signal-on detection of protein is proposed in this paper. Successful fabrication of the biosensor depends on ingenious
PMID 25463644

Tauroursodeoxycholic acid prevents stress induced aggregation of proteins in vitro and promotes PERK activation in HepG2 cells.

Gani AR1, Uppala JK1, Ramaiah KV2.
Archives of biochemistry and biophysics.Arch Biochem Biophys.2015 Feb 15;568:8-15. doi: 10.1016/j.abb.2014.12.031. Epub 2015 Jan 8.
Tauroursodeoxycholic acid (TUDCA) a bile salt and chemical chaperone reduces stress-induced aggregation of proteins; activates PERK [PKR (RNA-dependent protein kinase)-like ER (endoplasmic reticulum) kinase] or EIF2AK3, one of the hall marks of ER stress induced unfolded protein response (UPR) in hu
PMID 25579883