WordNet

a decrease in size of an organ caused by disease or disuse (同)wasting, wasting away
undergo atrophy; "Muscles that are not used will atrophy"
any weakening or degeneration (especially through lack of use) (同)withering

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1. 筋萎縮性側索硬化症およびその他の運動ニューロン疾患の診断 diagnosis of amyotrophic lateral sclerosis and other forms of motor neuron disease
2. 脊髄性筋萎縮症 spinal muscular atrophy
3. 関節リウマチの神経学的症状 neurologic manifestations of rheumatoid arthritis
4. 筋萎縮性側索硬化症の疫学および病因 epidemiology and pathogenesis of amyotrophic lateral sclerosis
5. 多系統萎縮症：予後および治療 multiple system atrophy prognosis and treatment

Kim DH, Kim JK, Kang JY.SourceDepartment of Neurology, Dong-A University College of Medicine, 1, 3-ga, Dongdaesing-dong, Seo-gu, Busan 602-715, Republic of Korea; Busan-Ulsan Regional Cardiocerebrovascular Center, Medical Science Research Center, Dong-A University College of Medicine, Busan, Republic of Korea.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia.J Clin Neurosci.2013 Jul 5. pii: S0967-5868(13)00065-9. doi: 10.1016/j.jocn.2012.09.052. [Epub ahead of print]
A 50-year-old woman presented with drowsiness, severe dysarthria, left facial palsy, and left hemiparesis. Diffusion-weighted MRI showed cerebral infarction in the left pontine tegmentum and right cerebellum and angiography revealed basilar artery occlusion. Altered consciousness and hemiparesis ful
PMID 23835466

Effects of nandrolone on recovery after neurotization of chronically denervated muscle in a rat model.

Isaacs J, Feher J, Shall M, Vota S, Fox MA, Mallu S, Razavi A, Friebe I, Shah S, Spita N.SourceDivision of Hand Surgery, Department of Orthopaedic Surgery, and.
Journal of neurosurgery.J Neurosurg.2013 Jul 5. [Epub ahead of print]
Object Suboptimal recovery following repair of major peripheral nerves has been partially attributed to denervation atrophy. Administration of anabolic steroids in conjunction with neurotization may improve functional recovery of chronically denervated muscle. The purpose of this study was to evalua
PMID 23829817

Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats.

Tong J, Huang C, Bi F, Wu Q, Huang B, Liu X, Li F, Zhou H, Xia XG.SourceDepartment of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
The EMBO journal.EMBO J.2013 Jul 3;32(13):1917-26. doi: 10.1038/emboj.2013.122. Epub 2013 May 28.
Mutation of Tar DNA-binding protein 43 (TDP-43) is linked to amyotrophic lateral sclerosis. Although astrocytes have important roles in neuron function and survival, their potential contribution to TDP-43 pathogenesis is unclear. Here, we created novel lines of transgenic rats that express a mutant
PMID 23714777

Ogata Tomonori
The Journal of Physical Fitness and Sports Medicine 1(1), 159-162, 2012
… Autophagic flux in skeletal muscle is induced not only by atrophic stimuli such as fasting and denervation, but also by physical exercise. … Excessive activation of autophagy promotes the progression of muscle atrophy. … In contrast, impaired or deficient autophagy appears to promote muscle weakness, myopathy, and age-related muscle atrophy due to the accumulation of denatured proteins and damaged organelles. …
NAID 130001930780

Intraductal injection of botulinum toxin induces functional changes in rat submandibular gland cells

Kuno Hiroshi,Uchihashi Kenji,Nishikawa Yasuo
Journal of Osaka Dental University 44(1), 65-75, 2010-04-00
… We investigated whether temporary acinar atrophy occurs simultaneously with chemical denervation of the glands. … Intraductal injection of BoNT induced a transient denervation of the submandibular gland, which is associated with reduced salivary secretion. … Morphological and ultra structural analyses of the cell organelles and secretory granules showed a clear atrophy of the acini, which was more prominent in glands treated with BoNT. …
NAID 110007592896

Familial Amyotrophic Lateral Sclerosis with a Novel G85S Mutation of Superoxide Dismutase 1 Gene: Clinical Features of Lower Motor Neuron Disease

Takazawa Takanori,Ikeda Ken,Hirayama Takehisa,Kawabe Kiyokazu,Nakamura Yoshikazu,Ito Hirono,Kano Osamu,Yoshii Yasuhiro,Tanaka Fumiaki,Sobue Gen,Iwasaki Yasuo
Internal Medicine 49(2), 183-186, 2010
… Muscle atrophy was presented in the left thigh. … Electromyography disclosed ongoing denervation muscle potentials in the left lower extremity. … Six months later, marked muscle weakness and atrophy expanded to four extremities. …
NAID 130000142286