delavirdine

出典: meddic

デラビルジン

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「a non-nucleoside reverse transcriptase inhibitor (trade name Rescriptor) used to treat AIDS and HIV」
Rescriptor

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/10/08 13:54:32」(JST)

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英文文献

  • Structural optimization of pyridine-type DAPY derivatives to exploit the tolerant regions of the NNRTI binding pocket.
  • Chen W1, Zhan P1, Daelemans D2, Yang J1, Huang B1, De Clercq E2, Pannecouque C3, Liu X4.
  • European journal of medicinal chemistry.Eur J Med Chem.2016 Oct 4;121:352-63. doi: 10.1016/j.ejmech.2016.05.054. Epub 2016 May 25.
  • Based on the crystallographic studies of diarylpyrimidines (DAPYs), we embarked on incorporating the hydrophilic piperidyl or morpholinyl group into the known DAPY derivatives bearing the pyridine moiety as a core structure, with the double aim to exploit additional interactions with the HIV-1 NNRTI
  • PMID 27267005
  • Antileishmanial activity of antiretroviral drugs combined with miltefosine.
  • Costa S1,2, Machado M3,4, Cavadas C2,5, do Céu Sousa M6,7.
  • Parasitology research.Parasitol Res.2016 Oct;115(10):3881-7. doi: 10.1007/s00436-016-5153-8. Epub 2016 Jun 1.
  • Co-infection of Leishmaniasis, a neglected tropical disease, with human immunodeficiency virus (HIV) has hindered treatment efficacy. In this study, we aim to evaluate the antileishmanial activity of two protease inhibitors (darunavir and atazanavir) and four reverse transcriptase inhibitors (tenofo
  • PMID 27249967
  • An accelerated background subtraction algorithm for processing high-resolution MS data and its application to metabolite identification.
  • Shekar V1, Shah A1, Shadid M1, Wu JT1, Bolleddula J1, Chowdhury S1.
  • Bioanalysis.Bioanalysis.2016 Aug;8(16):1693-707. doi: 10.4155/bio-2016-0101. Epub 2016 Jul 27.
  • BACKGROUND: Metabolite identification without radiolabeled compound is often challenging because of interference of matrix-related components.RESULTS: A novel and an effective background subtraction algorithm (A-BgS) has been developed to process high-resolution mass spectral data that can selective
  • PMID 27460980

和文文献

  • Pharmacokinetic interaction between amprenavir and delavirdine : evidence of induced clearance by amprenavir
  • Synthesis and Anti-HIV-1 Activity of New Delavirdine Analogues Carrying Arylpyrrole Moieties
  • Randomized study of saquinavir with ritonavir or nelfinavir together with delavirdine, adefovir, or both in human immunodeficiency virus-infected adults with virologic failure on indinavir : AIDS Clinical Trials Group Study 359

関連リンク

Drug information on Delavirdine for patients and consumers. ... What is delavirdine? Delavirdine is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in ...
Delavirdine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: excessive tiredness headache nausea diarrhea rash Some side effects can be serious. If you experience any of ...

関連画像

Delavirdine 200.svgDelavirdine - encyclopedia article Delavirdine | FDA Label - Tablet Delavirdine has the following structural Delavirdine.svgDelavirdine - Wikipedia, the free


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拡張検索delavirdine mesilate

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delavirdine mesilate」

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