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Giardia duodenalis 14-3-3 protein is polyglycylated by a tubulin tyrosine ligase-like member and deglycylated by two metallocarboxypeptidases.

Lalle M, Camerini S, Cecchetti S, Fantauzzi CB, Crescenzi M, Pozio E.SourceDepartment of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, 00161 Rome, Italy.
The Journal of biological chemistry.J Biol Chem.2011 Feb 11;286(6):4471-84. Epub 2010 Dec 6.
The flagellated protozoan Giardia duodenalis is a parasite of the upper part of the small intestine of mammals, including humans, and an interesting biological model. Giardia harbors a single 14-3-3 isoform, a multifunctional protein family, that is modified at the C terminus by polyglycylation, an
PMID 21135098

DPEP1, expressed in the early stages of colon carcinogenesis, affects cancer cell invasiveness.

Toiyama Y, Inoue Y, Yasuda H, Saigusa S, Yokoe T, Okugawa Y, Tanaka K, Miki C, Kusunoki M.SourceDepartment of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan.
Journal of gastroenterology.J Gastroenterol.2011 Feb;46(2):153-63. Epub 2010 Sep 8.
BACKGROUND: We investigated changes in the gene expression profile in colon cancer in order to identify gene markers that may be useful in the management of this disease.METHODS: The Cancer Genome Anatomy Project was used to detect differences in gene expression between normal and cancer tissue. The
PMID 20824289

CW-270033, a Novel Pyrrolidinyl-thio Carbapenem, Has Potent Antimicrobial Activity in Vitro and in Vivo(Miscellaneous)

KIM JongMyeung,HA Jong Ryul,OH Se Woong,KIM Hong Gi,LEE Jin-Man,LEE Dong Gun,LEE San-Han,KIM Jon Guk
Biological & pharmaceutical bulletin 30(3), 575-579, 2007-03-01
CW-270033, an injectable carbapenem, is a novel, synthesized pyrrolidinyl-thio carbapenem. In the present study, the in-vitro and in-vivo antibacterial activities of CW-270033 against wild-type strain …
NAID 110006239206