deficiency of PK

ピルビン酸キナーゼ欠乏症

WordNet

1. the 16th letter of the Roman alphabet (同)p
2. a river in western Thailand; a major tributary of the Chao Phraya (同)Ping River

PrepTutorEJDIC

1. 《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
2. 〈U〉〈C〉(…の)(量・額などの)不足,欠乏《+『of』(『in』)+『名』》 / 〈C〉不足分,不足量,不足額 / 〈C〉(精神・肉体などの)欠陥
3. parking
4. phosphorusの化学記号
5. OLD French古[代]フランス語

UpToDate Contents

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• 1. ピルビン酸キナーゼ欠損症 pyruvate kinase deficiency
• 2. 小児における溶血性貧血の概要 overview of hemolytic anemias in children
• 3. 新生児における血栓症のマネージメント management of thrombosis in the newborn
• 4. 赤血球抗原および抗体のプライマー a primer of red blood cell antigens and antibodies
• 5. 成人における抗癌剤の投与 dosing of anticancer agents in adults

English Journal

• Cost-efficient entrapment of β-glucosidase in nanoscale latex and silicone polymeric thin films for use as stable biocatalysts.

• Javed MR1, Buthe A2, Rashid MH3, Wang P4.
• Food chemistry.Food Chem.2016 Jan 1;190:1078-85. doi: 10.1016/j.foodchem.2015.06.040. Epub 2015 Jun 16.
• β-Glucosidase is an ubiquitous enzyme which has enormous biotechnological applications. Its deficiency in natural enzyme preparations is often overcome by exogenous supplementation, which further increases the enzyme utilization cost. Enzyme immobilization offers a potential solution through enzyme
• PMID 26213079

• Influence of intravenous thiamine supplementation on blood lactate concentration prior to cardiac surgery: A double-blinded, randomised controlled pilot study.

• Luger M1, Hiesmayr M, Köppel P, Sima B, Ranz I, Weiss C, König J, Luger E, Kruschitz R, Ludvik B, Schindler K.
• European journal of anaesthesiology.Eur J Anaesthesiol.2015 Aug;32(8):543-8. doi: 10.1097/EJA.0000000000000205.
• BACKGROUND: Stress related to surgery and critical illness depletes thiamine, essential in energy metabolism, and might result in high blood lactate concentrations and higher mortality.OBJECTIVES: We hypothesised that thiamine supplementation would increase blood concentration of thiamine and reduce
• PMID 26066773

• Treatment of pain in fibromyalgia patients with testosterone gel: Pharmacokinetics and clinical response.

• White HD1, Brown LA2, Gyurik RJ3, Manganiello PD4, Robinson TD5, Hallock LS6, Lewis LD7, Yeo KT8.
• International immunopharmacology.Int Immunopharmacol.2015 Aug;27(2):249-56. doi: 10.1016/j.intimp.2015.05.016. Epub 2015 May 21.
• To test our hypothesis that testosterone deficiency plays an important role in chronic pain, a Phase I/II pilot study was initiated with 12 fibromyalgia patients to verify that a daily dose for 28days with transdermal testosterone gel would 1) significantly and safely increase mean serum testosteron
• PMID 26004317

Japanese Journal

• Prekallikrein Deficiency in a Dog

• Okawa Takumi,Yanase Takuma,Shimokawa Miyama Takako [他],HIRAOKA Hiroko,BABA Kenji,TANI Kenji,OKUDA Masaru,MIZUNO Takuya
• Journal of
• … Prekallikrein (PK) deficiency is an uncommon disorder in dogs. … In this report, we describe a case of a dog that was referred for neurological defects and had a prolonged activated partial thromboplastin time (aPTT) and normal prothrombin time (PT) with no hemostatic defects. … By using human PK-deficient plasma, the dog was diagnosed to have PK deficiency. …
• NAID 130000307711

• 赤血球ピルビン酸キナーゼ(PK) (広範囲 血液・尿化学検査 免疫学的検査(第7版・2)その数値をどう読むか) -- (血球化学検査)

• 菅野 仁
• 日本臨床 68(-) (970), 885-889, 2010-01
• NAID 40016932983

• Prekallikrein (PK) Tokushima: PK deficiency caused by a Gly401 -> Glu mutation

• Shigekiyo T,Fujino O,Kanagawa Y,Matsumoto T
• JOURNAL OF
• NAID 120004211188

Related Links

• PK deficiency - definition of PK deficiency by Medical dictionary

Pyruvate Kinase Deficiency Definition Pyruvate kinase deficiency (PKD) is part of a group of disorders called hereditary nonspherocytic hemolytic anemias. ... We describe the implementation of a PK assay and document the first ...

• Cat PK Deficiency - UC Davis Veterinary Genetics Laboratory

Introduction Erythrocyte Pyruvate Kinase Deficiency (PK Deficiency) is an inherited hemolytic anemia caused by insufficient activity of this regulatory enzyme which results in instability and loss of red blood cells. The anemia is ...

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★リンクテーブル★

リンク元	「ピルビン酸キナーゼ欠乏症」
関連記事	「deficiency」「P」「PK」

「ピルビン酸キナーゼ欠乏症」

　　[★]

英

pyruvate kinase deficiency PK deficiency, PKD, deficiency of pyruvate kinase, deficiency of PK

同

ピルビン酸キナーゼ欠損症

関

ピルビン酸キナーゼ

• first aid step1 2006 p.89

遺伝

• 常染色体劣性遺伝

病態生理

• ピルビン酸キナーゼ pyruvate kinaseの著しい活性低下により赤血球内のATP産生が阻害される　→　ATP欠乏により赤血球の細胞膜よりカリウムが流出して溶血を来す。、

• 赤血球：ATP、ピルビン酸、NADの減少。2,3-DPGの増加

症状

• 黄疸、溶血性貧血

USMLE

• Q book p.140 39

「deficiency」

　　[★]

• n.

• 不足、欠乏、欠失、欠如、欠損、不十分。栄養不足、栄養素欠乏、欠乏症。(遺伝子)(染色体内の)遺伝子欠失
• 欠けているもの、不足している物。不足分。不完全なもの、欠点のあるもの

関

absence, agenesis, dearth, defect, defective, deficient, deficit, delete, deletion, deletional, depletion, deprivation, deprive, lack, miss, missing, morphological defect, paucity, scarce, scarcity, starve

　

「P」

　　[★]

• プロリン proline
• P波 P wave
• リン phosphorus

　 　 　

「PK」

　　[★]

• ピルビン酸キナーゼ pyruvate kinase