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- 1. 鉄過剰状態に対するキレート療法 chelation therapy for iron overload states
- 2. 急性鉄中毒 acute iron poisoning
- 3. Aluminum toxicity in chronic kidney disease
- 4. ムコール症（接合真菌症） mucormycosis zygomycosis
- 5. 腎性骨異栄養症の骨生検および診断 bone biopsy and the diagnosis of renal osteodystrophy
English Journal
- Longitudinal analysis of heart and liver iron in thalassemia major patients according to chelation treatment.
- Danjou F, Origa R, Anni F, Saba L, Cossa S, Podda G, Galanello R.SourceDipartimento di Sanità Pubblica, Medicina Clinica e Molecolare, Sezione di Scienze Biomediche e Biotecnologie, Università di Cagliari, Ospedale Regionale per le Microcitemie ASL8, Cagliari, Italy. Electronic address: fabdanjou@tiscali.it.
- Blood cells, molecules & diseases.Blood Cells Mol Dis.2013 Oct;51(3):142-5. doi: 10.1016/j.bcmd.2013.06.001. Epub 2013 Jun 28.
- Iron chelators and nuclear magnetic resonance imaging (MRI) techniques for assessing iron loading in liver and heart have greatly improved survival of thalassemic patients suffering iron overload-associated cardiomyopathy. However, the correlation between liver iron concentration and myocardial side
- PMID 23816436
- Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib.
- Louandre C, Ezzoukhry Z, Godin C, Barbare JC, Mazière JC, Chauffert B, Galmiche A.SourceInserm U1088, Faculté de Médecine, Université de Picardie Jules Verne, Amiens, France; Laboratoire de Biochimie, CHU Amiens, France.
- International journal of cancer. Journal international du cancer.Int J Cancer.2013 Oct 1;133(7):1732-42. doi: 10.1002/ijc.28159. Epub 2013 Apr 8.
- The multikinase inhibitor sorafenib is currently the treatment of reference for advanced hepatocellular carcinoma (HCC). In our report, we examined the cytotoxic effects of sorafenib on HCC cells. We report that the depletion of the intracellular iron stores achieved by using the iron chelator defer
- PMID 23505071
- Free iron catalyzes oxidative damage to hematopoietic cells/mesenchymal stem cells in vitro and suppresses hematopoiesis in iron overload patients.
- Lu W, Zhao M, Rajbhandary S, Xie F, Chai X, Mu J, Meng J, Liu Y, Jiang Y, Xu X, Meng A.SourceThe First Central Clinical College of Tianjin Medical University, Tianjin First Central Hospital, Tianjin, China.
- European journal of haematology.Eur J Haematol.2013 Sep;91(3):249-61. doi: 10.1111/ejh.12159. Epub 2013 Jul 15.
- OBJECTIVES: Transfusional iron overload is of major concern in hematological disease. Iron-overload-related dyserythropoiesis and reactive oxygen species (ROS)-related damage to hematopoietic stem cell (HSC) function are major setbacks in treatment for such disorders. We therefore aim to investigate
- PMID 23772810
Japanese Journal
- 症例報告 Secondary Hemochromatosis Accompanied by Diabetes Mellitus and Hypogonadism
- Nagai Takashi,Imamura Makoto,Negishi Teruo [他],Mori Masatomo
- The KITAKANTO medical journal 55(2), 145-149, 2005-05-01
- … After 30 months serum ferritin had decreased gradually to the normal range after daily 1,000mg injection of deferoxamine mesilate. …
- NAID 110001801382
- デフェロキサミンの耳毒性に関する モルモットを用いた実験的研究
- 山辺 習,菅野 秀貴
- 日本耳鼻咽喉科學會會報 101(8), 979-987, 1998-08-20
- … We investigated the possibility of ototoxicity by deferoxamine mesilate (DFO). …
- NAID 10005598485
- ラットを用いたシスプラチンの内耳・腎毒性 に対するデフェロキサミンの軽減効果 に関する実験的研究
- 渡部 浩伸,菅野 秀貴
- 日本耳鼻咽喉科學會會報 101(8), 967-978, 1998-08-20
- … On the other hand, deferoxiamine mesilate (DFO), an iron chelating agent, has been used for iron overloaded patients. …
- NAID 10005598420
Related Links
- Sigma-Aldrich offers Sigma-D9533, Deferoxamine mesylate salt for your research needs. Find product specific information including CAS, MSDS, protocols and references. ... Biochem/physiol Actions An iron chelator used often in ...
- Deferoxamine Mesilate Deferoxamine Mesylate Deferoxamine Methanesulfonate Deferoximine Deferrioxamine B Desferal Desferioximine Desferrioxamine Desferrioxamine B Desferrioxamine B Mesylate Desferroxamine Read this ...
Related Pictures
★リンクテーブル★
| 国試過去問 | 「078A048」 |
| リンク元 | 「デフェロキサミン」「desferrioxamine」 |
| 関連記事 | 「mesilate」 |
「078A048」
- 適切な組み合わせ。３つ。
- (1) Wilson病 － deferoxamine mesilate
- (2) ヘモクロマトーシス － L-dopa
- (3) Lesch-Nyhan症候群 － アロプリノール
- (4) ポルフィリン症 － クロルプロマジン
- (5) 痛風 － プロベネシド
「デフェロキサミン」
- キレート剤
- CAS:138-14-7
- C25H48N6O8･CH4SO3
適応
- 鉄中毒