プラスミノゲンアクチベーター放出障害
WordNet
- part with a possession or right; "I am relinquishing my bedroom to the long-term house guest"; "resign a claim to the throne" (同)relinquish, resign, free, give_up
- a process that liberates or discharges something; "there was a sudden release of oxygen"; "the release of iodine from the thyroid gland"
- a device that when pressed will release part of a mechanism (同)button
- activity that frees or expresses creative energy or emotion; "she had no other outlet for her feelings"; "he gave vent to his anger" (同)outlet, vent
- (music) the act or manner of terminating a musical phrase or tone (同)tone ending
- a formal written statement of relinquishment (同)waiver, discharge
- merchandise issued for sale or public showing (especially a record or film); "a new release from the London Symphony Orchestra"
- release (gas or energy) as a result of a chemical reaction or physical decomposition (同)free, liberate
- markedly subnormal in structure or function or intelligence or behavior; "defective speech"
- having a defect; "I returned the appliance because it was defective" (同)faulty
- (biology) any agency bringing about activation; a molecule that increases the activity of an enzyme or a protein that increases the production of a gene product in DNA transcription
- an inactive form of plasmin that occurs in plasma and is converted to plasmin by organic solvents
PrepTutorEJDIC
- (束縛・義務などから)〈人・動物など〉‘を'『自由にする』,解放する《+『名』+『from』+『名』》 / 〈矢など〉‘を'放つ,〈爆弾〉‘を'投下する;〈締めつけた物〉‘を'ゆるめて放す / 〈ニュースなど〉‘を'発表する;〈レコード・書籍など〉‘を'発売する,〈映画〉‘を'封切りする / (人に)〈権利など〉‘を'譲渡する《+『名』+『to』+『名』》 / (束縛・義務などからの)『解放』,放免,免除《+『from』+『名』》 / (ガスなどの)放出;(爆弾の)投下;(感情の)吐露《+『of』(『to』)+『名』》 / (ニュースなどの)発表;(映画などの)封切り,(レコードなどの)発表 / (機械の)作動装置,レリーズ
- 『欠点のある』,欠陥のある / 欠けている,足りない,(知能的に)標準以下の / 精神障害者,身体障害者
UpToDate Contents
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- 1. 止血の概要 overview of hemostasis
- 2. 2型糖尿病の病因 pathogenesis of type 2 diabetes mellitus
- 3. 血栓溶解異常による血栓性および出血性疾患 thrombotic and hemorrhagic disorders due to abnormal fibrinolysis
- 4. 静脈血栓症の原因の概要 overview of the causes of venous thrombosis
- 5. 血管内皮機能および血栓溶解療法の基本的メカニズム vascular endothelial function and fundamental mechanisms of fibrinolysis thrombolysis
English Journal
- Editorial: Exploring Lipid-related Treatment Options for the Treatment of NASH.
- Rizzo M, Montalto G, Vinciguerra M1.
- Current vascular pharmacology.Curr Vasc Pharmacol.2014;12(5):741-4.
- The liver plays a major role in lipid metabolism, importing free fatty acids (FFA) and manufacturing, storing and exporting lipids: derangements in any of these processes can lead to non-alcoholic fatty liver disease (NAFLD) [1]. NAFLD can be seen as the result of an imbalance between lipid availabi
- PMID 23305377
- Histone deacetylase inhibitors stimulate tissue-type plasminogen activator production in vascular endothelial cells.
- Larsson P1, Bergh N, Lu E, Ulfhammer E, Magnusson M, Wåhlander K, Karlsson L, Jern S.
- Journal of thrombosis and thrombolysis.J Thromb Thrombolysis.2013 Feb;35(2):185-92. doi: 10.1007/s11239-012-0831-6.
- A reduced capacity for acute tissue-type plasminogen activator (t-PA) release is likely to be associated with an impaired endogenous defense against intravascular thrombosis. Efficient approaches to pharmacologically restore a defective t-PA release have been lacking, but recent observations suggest
- PMID 23229086
- The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and mice.
- Bauman KA1, Wettlaufer SH, Okunishi K, Vannella KM, Stoolman JS, Huang SK, Courey AJ, White ES, Hogaboam CM, Simon RH, Toews GB, Sisson TH, Moore BB, Peters-Golden M.
- The Journal of clinical investigation.J Clin Invest.2010 Jun;120(6):1950-60. doi: 10.1172/JCI38369. Epub 2010 May 24.
- Plasminogen activation to plasmin protects from lung fibrosis, but the mechanism underlying this antifibrotic effect remains unclear. We found that mice lacking plasminogen activation inhibitor-1 (PAI-1), which are protected from bleomycin-induced pulmonary fibrosis, exhibit lung overproduction of t
- PMID 20501949
Japanese Journal
- <原著>糸球体腎炎における尿中plasminogen activator inhibitor-1の性質
- 田中 久夫
- 近畿大学医学雑誌 16(2), 283-297, 1991-06-25
- … It is assumed that the persistency of fibrin deposits in the kidney during renal diseases could reflect either a defective release of plasminogen activator (PA) or a local excess of plasminogen activator inhibitor (PAI). …
- NAID 110000060744
- 一過性のＴｉｓｓｕｅ‐ｔｙｐｅ ｐｌａｓｍｉｎｏｇｅｎ ａｃｔｉｖａｔｏｒ（ｔ‐ＰＡ）の低下を認めた深部静脈血栓症の１例
- 大野 秀子,松本 浩,松本 一美,吉岡 加寿夫,岡田 清孝,松尾 理
- 臨床血液 29(4), 571-576, 1988
- … He was treated with an intravenous infusion of t-PA, but could not obtain any good results.We thus supposed that he had a defective capacity to release t-PA from the blood vessel walls, and there was still a problem concerning the infusion methods of t-PA. …
- NAID 130004499259
Related Links
- Vascular plasminogen activator release was measured in 176 women with gynecologic malignancies and 92 normal women. Releasable plasminogen activator was conside ... Defective release of vascular plasminogen activator in ...
- In the present study 57 consecutive patients with a first episode of venographically proven deep vein thrombosis were investigated to evaluate the release of tissue-type plasminogen activator (t-PA) and of urokinase-type plasminogen ...
★リンクテーブル★
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- 英
- plasminogen activator deficiency
- 同
- プラスミノゲンアクチベーター放出障害 defective plasminogen activator release、プラスミノゲンアクチベーター低下症
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- 英
- defective plasminogen activator release
- 関
- プラスミノゲンアクチベーター欠乏症
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- 関
- absent、agenesis、defect、deficiency、deficient、deficit、deletion、deletional、devoid、drawback、fault、faulty、flaw、imperfect、imperfection、imperfectly、incomplete、incompletely、lack、miss、missing、vicious
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プラスミノーゲンアクチベーター, PA