decreased muscle tone

• 筋緊張低下

関

hypotonia、muscle hypotonia、muscular flaccidity、muscular hypotonia

WordNet

1. (of muscular tissue) the state of being hypotonic (同)hypotonus, hypotonicity
2. vary the pitch of ones speech (同)inflect, modulate
3. give a healthy elasticity to; "Lets tone our muscles" (同)tone up, strengthen
4. change the color or tone of; "tone a negative"
5. change to a color image; "tone a photographic image"
6. (linguistics) a pitch or change in pitch of the voice that serves to distinguish words in tonal languages; "the Beijing dialect uses four tones"
7. a steady sound without overtones; "they tested his hearing with pure tones of different frequencies" (同)pure tone
8. the quality of a persons voice; "he began in a conversational tone"; "he spoke in a nervous tone of voice" (同)tone of voice
9. a musical interval of two semitones (同)whole tone, step, whole step
10. the quality of something (an act or a piece of writing) that reveals the attitudes and presuppositions of the author; "the general tone of articles appearing in the newspapers is that the government should withdraw"; "from the tone of her behavior I gathe
11. utter monotonously and repetitively and rhythmically; "The students chanted the same slogan over and over again" (同)chant, intone
12. make smaller; "He decreased his staff" (同)lessen, minify
13. a process of becoming smaller or shorter (同)decrement
14. decrease in size, extent, or range; "The amount of homework decreased towards the end of the semester"; "The cabin pressure fell dramatically"; "her weight fell to under a hundred pounds"; "his voice fell to a whisper" (同)diminish, lessen, fall
15. the amount by which something decreases (同)decrement
16. the act of decreasing or reducing something (同)diminution, reduction, step-down
17. a change downward; "there was a decrease in his temperature as the fever subsided"; "there was a sharp drop-off in sales" (同)lessening, drop-off
18. make ones way by force; "He muscled his way into the office"
19. animal tissue consisting predominantly of contractile cells (同)muscular_tissue
20. one of the contractile organs of the body (同)musculus
21. authority or power or force (especially when used in a coercive way); "the senators used their muscle to get the party leader to resign"
22. having or distinguished by a tone; often used in combination; "full-toned"; "silver-toned"
23. having or characterized or distinguished by tone or a specific tone; often used in combination; "full-toned"; "shrill-toned"; "deep-toned"

PrepTutorEJDIC

1. 〈C〉(高さ・音色・長さ・音量の点から見た)『音』 / 〈C〉〈U〉音質 / 〈C〉楽音;全音程 / 〈C〉《しばしば複数形で》『言い方,書き方』,口調,語調 / 〈C〉支配的な(一般的な)風潮(傾向) / 〈U〉(筋肉などの緊張の)『正常な状態』 / 〈C〉『色調』,色合い,濃淡,明暗 / (音・色などで)…‘に'『ある調子(口調,色合い)をつける』 / …‘の'色を変える,色を補正する
2. …'を'『減らす』 / 『減る』,少なくなる / 〈U〉〈C〉(…の)『減少』,縮小《+『in』+『名』》 / 〈C〉(…の)減少量(額)《+『in』(『of』)+『名』》
3. 《方向》(1)(到着の意を含めて)…『へ』,に,まで / 《状況の変化》…[のほう]へ;…に[なるまで],その結果…になる / 《適用範囲》(1)《動詞に伴って》『…に対して』,に,へ / (2)《形容詞[句]・[代]名倍に伴って》『…に対して』 / 《程度・範囲》『…[に至る]まで』 / 《時間の終り》『…まで』(till) / 《to one's+『名』の形で》(…が)『…したことに[は]』 / 《比較・対比・割合》『…と比べて』,より,に対して / 《一致・適合》『…に合わせて』,に合って,に応じて / 《目的・意図》『…のために』 / 《運命・境遇》『…に』 / 《所属・関係》『…へ』,に[対して] / 《付加・付着・固執》『…に』 / 《対立・対向》…に[対して] / いつもの状態(位置)に / 停止(閉鎖)の状態に / 活動状態に(へ),仕事に
4. 《名詞的用法》『…すること』 / 《形容詞的用法》『…するための,すべき』 / 《副詞的用法》『…するために』,して,するとは,すれば / 《独立用法》 / 《文全体を修飾する慣用語句》…すれば,してみると,…だが / 短縮文
5. 〈U〉(動物体の組織としての)『筋肉』,筋(きん);〈C〉(体の各部を動かす)筋肉 / 〈U〉力,(特に)筋力,腕力 / 《俗に》(…に)強引に割り込む《+『in on』(『into, through』)+『名』》

UpToDate Contents

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• 1. 筋緊張低下および脱力を呈する幼児に対するアプローチ approach to the infant with hypotonia and weakness
• 2. 新生児における筋緊張低下を引き起こす末梢神経および筋肉の障害に関する概要 overview of peripheral nerve and muscle disorders causing hypotonia in the newborn
• 3. 筋力低下を呈する小児の病因および評価 etiology and evaluation of the child with muscle weakness
• 4. 新生児の神経学的検査 neurological examination of the newborn
• 5. SIDSを含む乳児の予期せぬ死亡：初期マネージメント sudden unexpected infant death including sids initial management

English Journal

• Novel c.191C>G (p.Pro64Arg) MPV17 mutation identified in two pairs of unrelated Polish siblings with mitochondrial hepatoencephalopathy.

• Piekutowska-Abramczuk D1, Pronicki M, Strawa K, Karkucińska-Więckowska A, Szymańska-Dębińska T, Fidziańska A, Więckowski MR, Jurkiewicz D, Ciara E, Jankowska I, Sykut-Cegielska J, Krajewska-Walasek M, Płoski R, Pronicka E.Author information 1Department of Medical Genetics.AbstractThis study reports clinical, biochemical and histopathological findings associated with a novel homozygous MPV17 mutation in four patients with mitochondrial depletion syndrome. The severe course of the disease, which started in the first weeks of life, was dominated by a failure to thrive, hypotonia and liver dysfunction, with relatively mild neurological involvement. All affected infants died by 1 year of age. Laboratory findings included progressive liver failure (hypertransaminasaemia, icterus, and coagulopathy), recurrent hypoglycaemia, lactic acidaemia, hyperferritinaemia, and increased transferrin saturation. Histological and ultrastructural analyses uncovered significant lipid accumulation in hepatocytes and myocytes. A severe decrease in the mitochondrial/nuclear DNA (mtDNA/nDNA) ratio was found post-mortem in the livers (and in one muscle specimen) of both examined patients. Oxidative phosphorylation system (OXPHOS) Western blotting revealed low levels of complexes I, III and IV subunits. The highlights of our findings are as follows: (i) The novel p.Pro64Arg mutation is the second recurrent MPV17 mutation reported. The phenotype associated with the p.Pro64Arg mutation differs from the phenotype of the relatively common p.Arg50Gln mutation, suggesting the existence of a genotype-phenotype correlation. (ii) Tissues collected from patients during autopsy may be useful for both mtDNA/nDNA ratio assessment and OXPHOS Western blotting.
• Clinical genetics.Clin Genet.2014 Jun;85(6):573-7. doi: 10.1111/cge.12228. Epub 2013 Jul 28.
• This study reports clinical, biochemical and histopathological findings associated with a novel homozygous MPV17 mutation in four patients with mitochondrial depletion syndrome. The severe course of the disease, which started in the first weeks of life, was dominated by a failure to thrive, hypotoni
• PMID 23829229

• Genotype-specific alterations in vascular smooth muscle cell function in cystic fibrosis piglets.

• Guo JJ1, Stoltz DA2, Zhu V1, Volk KA1, Segar JL1, McCray PB Jr1, Roghair RD3.Author information 1Department of Pediatrics, University of Iowa, Iowa City, IA 52242, United States.2Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, United States.3Department of Pediatrics, University of Iowa, Iowa City, IA 52242, United States. Electronic address: robert-roghair@uiowa.edu.AbstractBACKGROUND: The most common CF-causing mutations interfere with CFTR trafficking from the endoplasmic reticulum (CFTR-F508del) or prematurely terminate transcription (CFTR-null). We suspected that genotype-specific patterns of CFTR expression would have differential effects on smooth muscle cell calcium signaling and hence vascular tone. We hypothesized that compared to wild-type or CFTR-null aorta, aorta from CFTR-F508del (dF) piglets will have reduced endoplasmic reticulum calcium mobilization and decreased vasoconstriction.
• Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.J Cyst Fibros.2014 May;13(3):251-9. doi: 10.1016/j.jcf.2013.10.009. Epub 2013 Oct 31.
• BACKGROUND: The most common CF-causing mutations interfere with CFTR trafficking from the endoplasmic reticulum (CFTR-F508del) or prematurely terminate transcription (CFTR-null). We suspected that genotype-specific patterns of CFTR expression would have differential effects on smooth muscle cell cal
• PMID 24183914

• Clinical, Radiological, and Genetic Survey of Patients With Muscle-Eye-Brain Disease Caused by Mutations in POMGNT1.

• Yiş U1, Uyanik G2, Rosendahl DM3, Carman KB4, Bayram E5, Heise M2, Cömertpay G6, Kurul SH5.Author information 1Dokuz Eylül University, School of Medicine, Department of Pediatrics, Division of Child Neurology, İzmir, Turkey. Electronic address: ulyis@yahoo.com.2Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.3Institute of Human Genetics, Albert-Ludwigs University Medical Centre Freiburg, Freiburg, Germany.4Gaziantep Children's Hospital, Division of Child Neurology, Gaziantep, Turkey.5Dokuz Eylül University, School of Medicine, Department of Pediatrics, Division of Child Neurology, İzmir, Turkey.6Department of Medical Biology, Faculty of Medicine, Balcali Hospital, University of Cukurova, Adana, Turkey.AbstractBACKGROUND: To evaluate clinical, genetic, and radiologic features of our patients with muscle-eye-brain disease.
• Pediatric neurology.Pediatr Neurol.2014 May;50(5):491-7. doi: 10.1016/j.pediatrneurol.2014.01.008. Epub 2014 Jan 7.
• BACKGROUND: To evaluate clinical, genetic, and radiologic features of our patients with muscle-eye-brain disease.METHODS: The data of patients who were diagnosed with muscle-eye-brain disease from a cohort of patients with congenital muscular dystrophy in the Division of Pediatric Neurology of Dokuz
• PMID 24731844

Japanese Journal

• The immediate effect of PNF pattern on muscle tone and muscle stiffness in chronic stroke patient

• Journal of Physical Therapy Science 28(3), 967-970, 2016
• NAID 130005141176

• The effects of cervical traction, cranial rhythmic impulse, and Mckenzie exercise on headache and cervical muscle stiffness in episodic tension-type headache patients

• Journal of Physical Therapy Science 28(3), 837-843, 2016
• NAID 130005141143

• Effect of whole-body vibration exercise in a sitting position prior to therapy on muscle tone and upper extremity function in stroke patients

• Journal of Physical Therapy Science 28(2), 558-562, 2016
• NAID 130005127385

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★リンクテーブル★

リンク元	「hypotonia」「筋緊張低下」「muscle hypotonia」「muscular hypotonia」「muscular flaccidity」
関連記事	「decrease」「tone」「to」「muscle」

「hypotonia」

　　[★]

• n.

• 筋緊張低下、低張、低血圧、低圧

関

decreased muscle tone、hypobaric、low pressure、low-pressure、muscle hypotonia、muscular flaccidity、muscular hypotonia

　

「筋緊張低下」

　　[★]

英

hypotonia、muscle hypotonia、decreased muscle tone、muscular hypotonia

関

低圧、筋弛緩状態

英

hypotonus

「muscle hypotonia」

　　[★]

• 筋緊張低下

関

decreased muscle tone、hypotonia、muscular flaccidity、muscular hypotonia

「muscular hypotonia」

　　[★]

• 筋緊張低下

関

decreased muscle tone、hypotonia、muscle hypotonia、muscular flaccidity

「muscular flaccidity」

　　[★]

• 筋弛緩状態

関

decreased muscle tone、hypotonia、muscle hypotonia、muscular hypotonia

「decrease」

　　[★]

• vt.vi.

• 減少する/させる。縮小する/させる。(力・温度など)低下する/させる、衰える/衰えさせる

• n.

• 減少、縮小、低下。減少/縮小/低下の数/量/額/率/度合い

関

decline、depression、diminish、diminution、down-regulate、down-regulation、downregulate、downregulation、drop、fall、lessen、loss、lower、lowering、reduce、reduction、taper

　 　 　 　 　 　 　

「tone」

　　[★]

• n.

• 音、緊張、緊張度、トーン

関

sound、strain、stress、tonicity、tonus

　 　 　 　 　 　 　 　 　 　 　

「to」

　　[★]

• prep.

• ～の方向に向かって、～へ

「muscle」

　　[★]

• n.

• 筋肉