cytotoxic T lymphocytes

出典: meddic

細胞傷害性Tリンパ球 CTLs

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/10/25 01:30:10」(JST)

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  • Chimeric peptide containing both B and T cells epitope of tumor-associated antigen L6 enhances anti-tumor effects in HLA-A2 transgenic mice.
  • Lin SI1, Huang MH2, Chang YW2, Chen IH2, Roffler S3, Chen BM3, Sher YP4, Liu SJ5.
  • Cancer letters.Cancer Lett.2016 Jul 28;377(2):126-33. doi: 10.1016/j.canlet.2016.04.031. Epub 2016 Apr 26.
  • Synthetic peptides are attractive for cancer immunotherapy because of their safety and flexibility. In this report, we identified a new B cell epitope of tumor-associated antigen L6 (TAL6) that could induce antibody-dependent cellular cytotoxicity (ADCC) in vivo. We incorporated the B cell epitope w
  • PMID 27130449
  • Syntaxin 8 is required for efficient lytic granule trafficking in cytotoxic T lymphocytes.
  • Bhat SS1, Friedmann KS2, Knörck A3, Hoxha C4, Leidinger P5, Backes C6, Meese E7, Keller A8, Rettig J9, Hoth M10, Qu B11, Schwarz EC12.
  • Biochimica et biophysica acta.Biochim Biophys Acta.2016 Jul;1863(7 Pt A):1653-64. doi: 10.1016/j.bbamcr.2016.04.014. Epub 2016 Apr 17.
  • Cytotoxic T lymphocytes (CTL) eliminate pathogen-infected and cancerous cells mainly by polarized secretion of lytic granules (LG, containing cytotoxic molecules like perforin and granzymes) at the immunological synapse (IS). Members of the SNARE (soluble N-ethylmaleimide-sensitive factor attachment
  • PMID 27094127
  • Lentiviral vector encoding ubiquitinated hepatitis B core antigen induces potent cellular immune responses and therapeutic immunity in HBV transgenic mice.
  • Dai S1, Zhuo M1, Song L1, Chen X1, Yu Y1, Zang G2, Tang Z3.
  • Immunobiology.Immunobiology.2016 Jul;221(7):813-21. doi: 10.1016/j.imbio.2016.01.015. Epub 2016 Feb 2.
  • Predominant T helper cell type 1 (Th1) immune responses accompanied by boosted HBV-specific cytotoxic T lymphocyte (CTL) activity are essential for the clearance of hepatitis B virus (HBV) in chronic hepatitis B (CHB) patients. Ubiquitin (Ub) serves as a signal for the target protein to be recognize
  • PMID 26874581


  • In vivoにおける口腔レンサ球菌の抗腫瘍活性
  • 原 博志,長谷部 晃,佐伯 歩,阿部 亜美,山崎 裕,柴田 健一郎
  • 北海道歯学雑誌 35(1), 16-24, 2014-09
  • … As a first step in clarifying the mechanism by which they exhibit anti-tumor activity, the cytotoxic activities of lymphocytes of draining lymph nodes and spleens toward YAC-1 cells as a target (natural killer activity) or B16F0 melanoma cells as a target( tumor-specific cytotoxic T lymphocyte activity) were therefore measured on day 1 after the second immunization. …
  • NAID 120005476137
  • 腸管上皮内リンパ球の細胞傷害性T細胞への分化 (特集 組織における免疫応答の特性)
  • 若林 あや子,高橋 秀実
  • 臨床免疫・アレルギー科 62(1), 17-24, 2014-07
  • NAID 40020155219
  • CMLに対するWT1ペプチドワクチン療法によるWT1特異的CTLの長期間の増幅
  • 岩谷 俊平,成田 美和子,増子 正義 [他]
  • 新潟大学保健学雑誌 = Journal of health sciences of Niigata University 11(1), 83-91, 2014-03
  • NAID 40020114293


Cytotoxic T Lymphocytes (CTL) Cytotoxic T lymphocytes are lymphocytes that kill other ("target") cells. Targets may include: virus-infected cells (e.g., HIV-infected CD4 + T cells); cells infected with intracellular bacterial or protozoal ...
What are CTLs, or killer T-cells? Cytotoxic T lymphocytes (CTLs) are a subset of αβT-cells that usually express the CD8 co-receptor and have the ability to directly kill infected cells. What is the role of CTLs in the immune system? ...



関連記事T」「cytotoxic」「lymphocyte」「Ted」「T lymphocytes



cytotoxic T lymphocyte, CTL
細胞障害性Tリンパ球細胞溶解性Tリンパ球 cytolytic T lymphocyte
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  [★] 細胞傷害性Tリンパ球 cytotoxic T lymphocytes



WordNet   license wordnet

「the 20th letter of the Roman alphabet」

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  • adj.
  • 細胞傷害性の、細胞毒性の、細胞障害性の、細胞傷害の
cell injurycellular injurycytotoxicity

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「of or relating to substances that are toxic to cells」


  [★] リンパ球


WordNet   license wordnet

「an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection」
lymph cell



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「a tough youth of 1950''s and 1960''s wearing Edwardian style clothes」
Teddy boy

T lymphocytes」

  [★] T細胞Tリンパ球