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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/09/03 15:01:25」(JST)

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Cytidine triphosphate is a pyrimidine nucleoside triphosphate.

CTP is a substrate in the synthesis of RNA.

CTP is a high-energy molecule similar to ATP, but its role as an energy coupler is limited to a much smaller subset of metabolic reactions. CTP is a coenzyme in metabolic reactions like the synthesis of glycerophospholipids and glycosylation of proteins.

CTP acts as an inhibitor of the enzyme Aspartate carbamoyltransferase, which is used in pyrimidine biosynthesis.^[1]

References

^ Blackburn, G. Michael. Nucleic Acids in Chemistry and Biology. The Royal Society of Chemistry, 2006, p. 119-120.

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English Journal

Effect of the use of combination uridine triphosphate, cytidine monophosphate, and hydroxycobalamin on the recovery of neurosensory disturbance after bilateral sagittal split osteotomy: a randomized, double-blind trial.

Vieira CL1, Vasconcelos BC2, Leão JC3, Laureano Filho JR4.
International journal of oral and maxillofacial surgery.Int J Oral Maxillofac Surg.2015 Oct 9. pii: S0901-5027(15)01324-7. doi: 10.1016/j.ijom.2015.09.007. [Epub ahead of print]
The change in neurosensory lesions that develop after bilateral sagittal split osteotomy (BSSO) was explored, and the influence of the application of combination uridine triphosphate (UTP), cytidine monophosphate (CMP), and hydroxycobalamin (vitamin B12) on patient outcomes was assessed. This was a
PMID 26458536

Maltose modified poly(propylene imine) dendrimers as potential carriers of nucleoside analog 5'-triphosphates.

Szulc A1, Signorelli M2, Schiraldi A2, Appelhans D3, Voit B3, Bryszewska M4, Klajnert-Maculewicz B4, Fessas D2.
International journal of pharmaceutics.Int J Pharm.2015 Oct 9;495(2):940-947. doi: 10.1016/j.ijpharm.2015.09.065. [Epub ahead of print]
Poly(propylene imine) (PPI) dendrimers contained surface maltose modification are proposed as drug carriers for nucleoside analog (NA) 5'-triphosphates. The aim of this study was to investigate the interactions between PPI dendrimers of 3rd (G3) or 4th (G4) generation and cytidine-5'-triphosphate (C
PMID 26456295

Conventional and Unconventional Mechanisms For Soluble Guanylyl Cyclase Signaling.

Gao Y1.
Journal of cardiovascular pharmacology.J Cardiovasc Pharmacol.2015 Oct 8. [Epub ahead of print]
Soluble guanylate cyclase (sGC) is the principal enzyme in mediating the biological actions of nitric oxide (NO). Upon activation, sGC converts guanosine triphosphate (GTP) to guanosine 3', 5'-cyclic monophosphate (cGMP), which mediating diverse physiological processes including vasodilation, platel
PMID 26452163

Japanese Journal

Blockade of Cytidine Triphosphate Synthase Regulates Smooth Muscle Cell and Endothelial Cell Proliferation Differentially

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 33(10), 2286-2287, 2013
NAID 120005597682

A CMP-N-acetylneuraminic Acid Synthetase Purified from a Marine Bacterium, Photobacterium leiognathi JT-SHIZ-145

Bioscience, biotechnology, and biochemistry 75(1), 47-53, 2011-01-23
NAID 10027896580

Development of a sensitive and selective LC/MS/MS method for the simultaneous determination of intracellular 1-beta-D-arabinofuranosylcytosine triphosphate (araCTP), cytidine triphosphate (CTP) and deoxycytidine triphosphate (dCTP) in a human follicular lymphoma cell line

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 877(14), 1417-1425, 2009-05-15
NAID 10028017352

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リンク元	「CTP」「シチジン三リン酸」
関連記事	「triphosphate」

「CTP」

Cytidine triphosphate
Names
	IUPAC name [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl(hydroxy-phosphonooxyphosphoryl)hydrogen phosphate
	Other names CTP; Cytidine-5'-triphosphate; Cytidine 5'-(tetrahydrogen triphosphate)
Identifiers
CAS Number	65-47-4
ChemSpider	19952488
IUPHAR/BPS	1741
Jmol 3D model	Interactive image; Interactive image
MeSH	Cytidine+triphosphate
PubChem	6176
	InChI InChI=1S/C9H13N3O5.3H3O4P/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;31-5(2,3)4/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);3(H3,1,2,3,4)/t4-,6-,7-,8-;;;/m1.../s1 Key: NPIWPFUCEAMYFN-LLWADOMFSA-N ; InChI=1/C9H16N3O14P3/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 Key: PCDQPRRSZKQHHS-XVFCMESIBL ; InChI=1/C9H13N3O5.3H3O4P/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;31-5(2,3)4/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);3(H3,1,2,3,4)/t4-,6-,7-,8-;;;/m1.../s1 Key: NPIWPFUCEAMYFN-LLWADOMFBY ;
	SMILES c1cn(c(=O)nc1N)[C@H]2[C@@H]([C@@H]([C@H](O2)CO[P@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)O)O ; OP(O)(=O)O.OP(O)(=O)O.OP(O)(=O)O.N/C1=N/C(=O)N(/C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O ;
Properties
Chemical formula	C9H16N3O14P3
Molar mass	483.156
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references