cyclin-dependent kinase inhibitor p16

サイクリン依存性キナーゼ阻害因子p16

WordNet

1. limit, block, or decrease the action or function of; "inhibit the action of the enzyme"; "inhibit the rate of a chemical reaction"
2. control and refrain from showing; of emotions, desires, impulses, or behavior (同)bottle up, suppress
3. limit the range or extent of; "Contact between the young was inhibited by strict social customs"
4. relying on or requiring a person or thing for support, supply, or what is needed; "dependent children"; "dependent on moisture"
5. addicted to a drug (同)dependant, drug-addicted, hooked, strung-out
6. contingent on something else (同)dependant, qualified
7. (of a clause) unable to stand alone syntactically as a complete sentence; "a subordinate (or dependent) clause functions as a noun or adjective or adverb within a sentence" (同)subordinate
8. a substance that retards or stops an activity
9. an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
10. the basic unit of money in Papua New Guinea

PrepTutorEJDIC

1. 〈感情・欲望・行動・作用など〉‘を'抑制する / (…しないように)〈人〉‘を'抑制する,妨げる《+『名』+『from』+『名』(do『ing』)》
2. 『頼っている』,依存している,従属している / 扶養される人(家族)
3. 抑制する人(物) / 化学反応抑制剤

UpToDate Contents

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• 1. 黒色腫（メラノーマ）に対する遺伝的感受性 inherited susceptibility to melanoma
• 2. 頭頸部の扁平上皮癌化：分子学的および遺伝学的変化 head and neck squamous cell carcinogenesis molecular and genetic alterations
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• 5. 転移性ホルモン受容体陽性乳癌に対する治療アプローチ：内分泌療法 treatment approach to metastatic hormone receptor positive breast cancer endocrine therapy

English Journal

• Multiple neurofibromas as the presenting feature of familial atypical multiple malignant melanoma (FAMMM) syndrome.

• Vanneste R, Smith E, Graham G.SourceDepartment of Medical Genetics, McGill University Health Centre, Montreal, Canada.
• American journal of medical genetics. Part A.Am J Med Genet A.2013 Jun;161(6):1425-31. doi: 10.1002/ajmg.a.35884. Epub 2013 Apr 23.
• Mutations in the cyclin-dependent kinase inhibitor-2A (CDKN2A) gene have been associated with a number of malignancies, most notably cutaneous malignant melanoma (CMM). Mutations in this gene have also been associated with pancreatic cancer and breast cancer, as well as astrocytomas and other nervou
• PMID 23613284

• Prognostic value of p16 expression and alcohol consumption in Japanese patients with oropharyngeal squamous cell carcinoma.

• Saito Y, Yoshida M, Ushiku T, Omura G, Ebihara Y, Shimono T, Fukayama M, Yamasoba T, Asakage T.SourceDepartment of Otolaryngology and Head and Neck Surgery, University of Tokyo, Tokyo, Japan.
• Cancer.Cancer.2013 Jun 1;119(11):2005-11. doi: 10.1002/cncr.28015. Epub 2013 Mar 15.
• BACKGROUND: The prevalence and prognostic value of human papillomavirus-related oropharyngeal squamous cell carcinoma (OPSCC) in Japan has not been evaluated.METHODS: Over a 12-year period, the authors used immunohistochemistry to evaluate the expression of p16 (a cyclin-dependent kinase inhibitor a
• PMID 23504914

• Cyclin-dependent kinase inhibitor 2A (p16) distinguishes well-differentiated liposarcoma from lipoma.

• Gonzalez RS, McClain CM, Chamberlain BK, Coffin CM, Cates JM.SourceDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
• Histopathology.Histopathology.2013 Jun;62(7):1109-11. doi: 10.1111/his.12112. Epub 2013 Apr 22.
• PMID 23600700

Japanese Journal

• p16 and p27 are functionally correlated during the progress of hepatocarcinogenesis

• MATSUDA Yasunobu,ICHIDA Takafumi
• Medical molecular morphology : official journal of the Japanese Society for Clinical Molecular Morphology 39(4), 169-175, 2006-12-01
• NAID 10018659153

• Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

• JANZEN V
• Nature 443, 421-426, 2006
• NAID 80018980931

• Cell Cycle Regulator Expression After Coronary Stenting in Humans Immunohistochemical Examination : bImmunohistochemical Examination/b

• Sakai Tetsuo,Inoue Shin,Otsuka Toshihiko,Matsuyama Taka-aki,Saito Tsukasa,Murakami Mikitaka,Ota Hidekazu,Katagiri Takashi
• Japanese Heart Journal 45(1), 133-145, 2004
• … Sections were stained with antibodies against platelet-derived growth factor (PDGF), basic fibroblast growth factor (b-FGF), cyclin D1, p16, p21, and p27. …
• NAID 130000067282

Related Links

• OMIM Entry - * 600160 - CYCLIN-DEPENDENT KINASE ...

600160 - CYCLIN-DEPENDENT KINASE INHIBITOR 2A; CDKN2A - CDKN2;; CDK4 INHIBITOR;; MULTIPLE TUMOR SUPPRESSOR 1; MTS1;; TP16;; p16(INK4);; p16(INK4A) - p14(ARF), INCLUDED;; p12 ...

• Cdkn2a cyclin-dependent kinase inhibitor 2A [Mus musculus ...

Gene ID: 12578, updated on 6-May-2014 Summary Other designations CDK4I, cyclin-dependent kinase 4 inhibitor A, cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2A ...

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★リンクテーブル★

リンク元	「サイクリン依存性キナーゼ阻害因子p16」
関連記事	「inhibit」「inhibitor」「dependent」「kinase」「dependent kinase」

「サイクリン依存性キナーゼ阻害因子p16」

　　[★]

英

cyclin-dependent kinase inhibitor p16

「inhibit」

　　[★]

• v.

• 抑制する、阻害する、阻止する

関

abrogate、block、depress、depression、deter、inhibition、interdict、prevent、prevention、repress、repression、restrain、restraint、suppress、suppression

　 　 　 　

「inhibitor」

　　[★]

• n.

• 阻害剤、阻害薬、抑制薬、抑制剤、(内在性物質について)インヒビター、抑制物質

関

blocker、depressant、suppressant

　 　

「dependent」

　　[★]

• adj.

• 依存性の、依存的な、依存型の、依存の

関

depend、dependence、dependency、dependently

　 　 　 　 　

「kinase」

　　[★] キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase 　

「dependent kinase」

　　[★]

• 依存性キナーゼ、依存性リン酸化酵素