WordNet

a straight line that generates a cylinder or cone
one of four substances thought in ancient and medieval cosmology to constitute the physical universe; "the alchemists believed that there were four elements"
the situation in which you are happiest and most effective; "in your element"
the most favorable environment for a plant or animal; "water is the element of fishes"
of a compound having atoms arranged in a ring structure
recurring in cycles (同)cyclical
conforming to the Carnot cycle
forming a whorl or having parts arranged in a whorl; "cyclic petals"; "cyclic flowers"
marked by repeated cycles
readily reacting or replying to people or events or stimuli; showing emotion; "children are often the quickest and most responsive members of the audience"
containing or using responses; alternating; "responsive reading"; "antiphonal laughter" (同)antiphonal
the 1st letter of the Roman alphabet (同)a
the blood group whose red cells carry the A antigen (同)type_A, group A
violent or severe weather (viewed as caused by the action of the four elements); "they felt the full fury of the elements"

PrepTutorEJDIC

〈C〉(物質を構成する)元素 / 〈C〉《修飾語[句]を伴って》(…の)(基本的な)『要素』,『成分』;《しばしば複数形で》構成分子 / 〈C〉(生物に固有の)生息場所,環境;(人の)適所,本領 / 〈C〉《古》四大(しだい)[元素](自然界の基本的構成要素と考えられていた地(earth)・水(water)・風(air)・火(fire)の4大要素の一つ) / 《the elements》(雨・風・雪などの)自然力・風雨,(特に)悪天候 / 《the elements》(学問の)原理,初歩,概論
すぐ反応する,共鳴しやすい;応答する
answer / ampere

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1. 軟部および骨肉腫の病原因子 pathogenetic factors in soft tissue and bone sarcomas
2. ステロイド抵抗性喘息 glucocorticoid resistant asthma
3. 血小板生物学 platelet biology
4. 甲状腺ホルモンの作用 thyroid hormone action
5. 原発性色素沈着性結節性副腎皮質病変によるクッシング症候群 cushings syndrome due to primary pigmented nodular adrenocortical disease

Involvement of dopaminergic and cholinergic systems in social isolation-induced deficits in social affiliation and conditional fear memory in mice.

Okada R1, Fujiwara H1, Mizuki D1, Araki R2, Yabe T2, Matsumoto K3.
Neuroscience.Neuroscience.2015 Jul 23;299:134-45. doi: 10.1016/j.neuroscience.2015.04.064. Epub 2015 May 2.
Post-weaning social isolation rearing (SI) in rodents elicits various behavioral abnormalities including attention deficit hyperactivity disorder-like behaviors. In order to obtain a better understanding of SI-induced behavioral abnormalities, we herein investigated the effects of SI on social affil
PMID 25943484

Ma JC1, Duan MJ1, Sun LL1, Yan ML1, Liu T1, Wang Q1, Liu CD1, Wang X1, Kang XH1, Pei SC1, Zong DK1, Chen X1, Wang N1, Ai J2.
Neuroscience.Neuroscience.2015 Jul 23;299:66-78. doi: 10.1016/j.neuroscience.2015.04.061. Epub 2015 May 2.
Large cohort studies have revealed a close relationship between cognitive impairment and cardiovascular diseases, although the mechanism underlying this relationship remains incompletely understood. In this study, using a transgenic (Tg) mouse model of cardiac-specific over-expression of microRNA-1-
PMID 25943483

Decrease of phosphorylated proto-oncogene CREB at Ser 133 site inhibits growth and metastatic activity of renal cell cancer.

Wang X1, Ren Y, Zhuang H, Meng X, Huang S, Li Y, Hehir M, Wang P.
Expert opinion on therapeutic targets.Expert Opin Ther Targets.2015 Jun 3:1-11. [Epub ahead of print]
OBJECTIVE: Cyclic-AMP-responsive element-binding protein (CREB) is a proto-oncogenic transcription factor. The authors' previous reports showed that blocking the CREB binding site at Ser 133 inhibited the expression of target genes, which related to the progression of some tumors. In this study, the
PMID 26036429

定本久世
比較生理生化学 26(4), 163-168, 2009-11-20
　軟体動物腹足類（Gastropoda）は，神経細胞サイズが大きく，中枢神経系に含まれる細胞数も少ない。このため，古くから特定行動に関わる神経回路研究に利用されてきた。本総説では，長期記憶の基となるシナプス可塑性に関わる分子メカニズムについて，ヨーロッパモノアラガイ（<I>Lymnaea stagnalis</I>）の味覚嫌悪学習におけるこれまでに得られた結果をまとめた。 …
NAID 10026144920

BBF2H7, a Novel Transmembrane bZIP Transcription Factor, Is a New Type of Endoplasmic Reticulum Stress Transducer

Kondo Shinichi,Saito Atsushi,Hino Shin-ichiro,Murakami Tomohiko,Ogata Maiko,Kanemoto Soshi,Nara Satoshi,Yamashita Akinori,Yoshinaga Kazuya,Hara Hideaki,Imaizumi Kazunori
Molecular and cellular biology 27(5), 1716-1729, 2007-03
… The cleaved fragments of BBF2H7 translocate into the nucleus and can bind directly to cyclic AMP-responsive element sites to activate transcription of target genes. …
NAID 120001643276

Lithium : Potential Therapeutics Against Acute Brain Injuries and Chronic Neurodegenerative Diseases

WADA Akihiko,YOKOO Hiroki,YANAGITA Toshihiko,KOBAYASHI Hideyuki
Journal of pharmacological sciences 99(4), 307-321, 2005-12-20
… treatment of lithium, in agreement with the delayed-onset of mood-stabilizing effects of lithium, up-regulates cell survival molecules (e.g., Bcl-2, cyclic AMP-responsive element binding protein, brain-derived neurotrophic factor, Grp78, Hsp70, and β-catenin), while down-regulating pro-apoptotic activities (e.g., excitotoxicity, p53, Bax, caspase, cytochrome c release, β-amyloid peptide production, and tau hyperphosphorylation), thus preventing or even reversing …
NAID 10025731486