creutzfeldt-Jakob disease

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/02/21 15:38:13」(JST)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2018/02/11 18:02:44」(JST)

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  • Progressive MRI Findings in Creutzfeldt-Jakob Disease.
  • Kulkarni KM1.
  • Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society.J Neuroophthalmol.2015 Mar;35(1):96-98.
  • PMID 25295685
  • The glycosylation status of PrPC is a key factor in determining TSE transmission between species.
  • Wiseman FK1, Cancellotti E1, Piccardo P2, Iremonger K1, Boyle A1, Brown D1, Ironside JW3, Manson JC1, Diack AB4.
  • Journal of virology.J Virol.2015 Feb 11. pii: JVI.02296-14. [Epub ahead of print]
  • The risk of transmission of Transmissible Spongiform Encephalopathies (TSE) between different species has been notoriously unpredictable because the mechanisms of transmission are not fully understood. A transmission barrier between species often prevents infection of a new host with a TSE agent. No
  • PMID 25673720
  • Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation.
  • Lau A1, McDonald A2, Daude N3, Mays CE3, Walter ED2, Aglietti R2, Mercer RC3, Wohlgemuth S3, van der Merwe J3, Yang J3, Gapeshina H3, Kim C4, Grams J3, Shi B3, Wille H5, Balachandran A6, Schmitt-Ulms G7, Safar JG4, Millhauser GL2, Westaway D8.
  • EMBO molecular medicine.EMBO Mol Med.2015 Feb 6. pii: e201404588. doi: 10.15252/emmm.201404588. [Epub ahead of print]
  • The cellular prion protein (PrPC) comprises a natively unstructured N-terminal domain, including a metal-binding octarepeat region (OR) and a linker, followed by a C-terminal domain that misfolds to form PrPS c in Creutzfeldt-Jakob disease. PrPC β-endoproteolysis to the C2 fragment allows PrPS c fo
  • PMID 25661904


  • Relationships between Clinicopathological Features and Cerebrospinal Fluid Biomarkers in Japanese Patients with Genetic Prion Diseases
  • Higuma Maya,Sanjo Nobuo,Satoh Katsuya,Shiga Yusei,Sakai Kenji,Nozaki Ichiro,Hamaguchi Tsuyoshi,Nakamura Yosikazu,Kitamoto Tetsuyuki,Shirabe Susumu,Murayama Shigeo,Yamada Masahito,Tateishi Jun,Mizusawa Hidehiro
  • PLoS ONE 8(3), e60003, 2013-03-28
  • … We retrospectively analyzed age at onset and disease duration; … Three clinical phenotypes were seen: rapidly progressive Creutzfeldt-Jakob disease (CJD), which included 100% of E200K cases, 70% of M232R, and 21% of P102L; … and Gerstmann-Sträussler-Scheinker disease, which included 100% of P105L and 79% of P102L. … Patients negative for PrPSc in the CSF were older at disease onset than positive patients. …
  • NAID 120005231333
  • Early Detection of Abnormal Prion Protein in Genetic Human Prion Diseases Now Possible Using Real-Time QUIC Assay
  • Sano Kazunori,Satoh Katsuya,Atarashi Ryuichiro,Takashima Hiroshi,Iwasaki Yasushi,Yoshida Mari,Sanjo Nobuo,Murai Hiroyuki,Mizusawa Hidehiro,Schmitz Matthias,Zerr Inga,Kim Yong-Sun,Nishida Noriyuki
  • PLoS ONE 8(1), e54915, 2013-01-25
  • … We recently developed a new in vitro amplification technology, designated "real-time quaking-induced conversion (RT-QUIC)", to detect the abnormal form of prion protein in CSF from sporadic Creutzfeldt-Jakob disease (sCJD) patients. …
  • NAID 120005230763
  • 症例報告 経過2年で死亡した家族性クロイツフェルト・ヤコブ病プリオン蛋白コドン180変異例
  • 小野 広一,武田 昌治,小川 喜輝 [他]
  • 広島医学 65(3), 193-199, 2012-03-00
  • NAID 40019258576


Creutzfeldt-Jakob Disease (CJD) information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). ... What is Creutzfeldt-Jakob Disease? Creutzfeldt-Jakob disease (CJD) is a rare ...
... vCJD; CJD; Jacob-Creutzfeldt disease Images Creutzfeldt-Jakob disease Central nervous system and peripheral nervous system References Bosque PJ, Tyler KL. Prions and prion diseases of the central nervous system ...



関連記事disease」「diseased」「Creutzfeldt-Jakob disease」「Jakob」「Creutzfeldt


  [★] クロイツフェルト・ヤコブ病 Creutzfelt-Jakob病 Creutzfeldt-Jakob disease



  • n.
疾患illnessより厳密な概念。「ある臓器に明確な障害が確認され、それによって症状が出ているとはっきり説明できる場合」 (PSY.9)
特定の原因、病態生理、症状、経過、予後、病理組織所見が全てそろった場合 (PSY.9)
  • something that is very wrong with people's attitudes, way of life or with society.
ailailmentdisease entitydisorderillillnessmaladysicksickness
  • 注意

WordNet   license wordnet

「an impairment of health or a condition of abnormal functioning」

PrepTutorEJDIC   license prepejdic

「(体の)『病気』,疾患 / (精神・道徳などの)病気,病弊」

PrepTutorEJDIC   license prepejdic

「女性の話術芸人 =diseur」



WordNet   license wordnet

「caused by or altered by or manifesting disease or pathology; "diseased tonsils"; "a morbid growth"; "pathologic tissue"; "pathological bodily processes"」
morbid, pathologic, pathological

PrepTutorEJDIC   license prepejdic

「病気にかかった / 病的な,不健全な(morbid)」

Creutzfeldt-Jakob disease」

  [★] クロイツフェルト・ヤコブ病 CJD