WordNet

undergo a test; "She doesnt test well"
any standardized procedure for measuring sensitivity or memory or intelligence or aptitude or personality etc; "the test was standardized on a large sample of students" (同)mental test, mental testing, psychometric test
the act of undergoing testing; "he survived the great test of battle"; "candidates must compete in a trial of skill" (同)trial
the act of testing something; "in the experimental trials the amount of carbon was measured separately"; "he called each flip of the coin a new trial" (同)trial, run
a hard outer covering as of some amoebas and sea urchins
put to the test, as for its quality, or give experimental use to; "This approach has been tried with good results"; "Test this recipe" (同)prove, try, try out, examine, essay
achieve a certain score or rating on a test; "She tested high on the LSAT and was admitted to all the good law schools"
determine the presence or properties of (a substance)
show a certain characteristic when tested; "He tested positive for HIV"
the act of tolerating something
the power or capacity of an organism to tolerate unfavorable environmental conditions
willingness to recognize and respect the beliefs or practices of others
an examination of the characteristics of something; "there are laboratories for commercial testing"; "it involved testing thousands of children for smallpox"
the act of subjecting to experimental test in order to determine how well something works; "they agreed to end the testing of atomic weapons"
a corticosteroid hormone (trade name Cortone Acetate) normally produced by the adrenal cortex; is converted to hydrocortisone (同)Cortone Acetate
tested and proved useful or correct; "a tested method" (同)tried, well-tried
tested and proved to be reliable (同)time-tested, tried, tried and true

PrepTutorEJDIC

(人の能力などの)『試験』,考査,テスト / (物事の)『試験』,検済,試錬,実験《+of+名》 / 化学分析;試薬 / =test match / …‘を'『試験する』,検査する / …‘を'化学分析する / (…の)試験を受ける,試験をする《+for+名》
(自分と異なる他人の意見・行動などを許す)寛大,寛容・我慢（がまん）,忍耐力 / (薬品・毒物などに対する)耐性,抗毒性 / 公差,許容誤差
コーチゾン(副腎皮質から出るほるもん)

UpToDate Contents

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1. 小児および思春期における2型糖尿病の疫学、症状、および診断 epidemiology presentation and diagnosis of type 2 diabetes mellitus in children and adolescents
2. 妊娠中の糖尿病：スクリーニングおよび診断 diabetes mellitus in pregnancy screening and diagnosis
3. インスリン分泌および膵β細胞の機能 insulin secretion and pancreatic beta cell function
4. 小児および思春期における1型糖尿病の疫学、症状、および診断 epidemiology presentation and diagnosis of type 1 diabetes mellitus in children and adolescents
5. 先端巨大症の診断 diagnosis of acromegaly

English Journal

Safety, efficacy and weight effect of two 11β-HSD1 inhibitors in metformin-treated patients with type 2 diabetes.

Heise T1, Morrow L, Hompesch M, Häring HU, Kapitza C, Abt M, Ramsauer M, Magnone MC, Fuerst-Recktenwald S.
Diabetes, obesity & metabolism.Diabetes Obes Metab.2014 Nov;16(11):1070-7. doi: 10.1111/dom.12317. Epub 2014 Jun 9.
AIMS: We assessed safety and efficacy of two selective 11β-HSD1 inhibitors (RO5093151/RO-151 and RO5027383/RO-838) in this randomized, controlled study in metformin-treated patients with type 2 diabetes.METHODS: Patients either received placebo (N = 21), RO-151 BID 5 mg (N = 24) or 200 mg (N = 20)
PMID 24828020

HIS-388, a novel orally active and long-acting 11β-hydroxysteroid dehydrogenase type 1 inhibitor, ameliorates insulin sensitivity and glucose intolerance in diet-induced obesity and nongenetic type 2 diabetic murine models.

Okazaki S1, Takahashi T2, Iwamura T1, Nakaki J1, Sekiya Y1, Yagi M1, Kumagai H1, Sato M1, Sakami S1, Nitta A1, Kawai K1, Kainoh M1.
The Journal of pharmacology and experimental therapeutics.J Pharmacol Exp Ther.2014 Oct;351(1):181-9. doi: 10.1124/jpet.114.216556. Epub 2014 Aug 6.
11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) is considered a potential therapeutic target in the treatment of type 2 diabetes mellitus. In this study, we investigated the pharmacological properties of HIS-388 (N-[(1R,2s,3S,5s,7s)-5-hydroxyadamantan-2-yl]-3-(pyridin-2-yl) isoxazole-4-carboxam
PMID 25100752

A novel 11β-HSD1 inhibitor improves diabesity and osteoblast differentiation.

Park JS1, Bae SJ, Choi SW, Son YH, Park SB, Rhee SD, Kim HY, Jung WH, Kang SK, Ahn JH, Kim SH, Kim KY.
Journal of molecular endocrinology.J Mol Endocrinol.2014 Mar 6;52(2):191-202. doi: 10.1530/JME-13-0177. Print 2014 Apr.
Selective inhibitors of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) have considerable potential as treatment for osteoporosis as well as metabolic syndrome including type 2 diabetes mellitus. Here, we investigated the anti-diabetic, anti-adipogenic, and anti-osteoporotic activity of KR-6750
PMID 24444497

Japanese Journal

Hypoadrenocorticismにおける赤血球インスリン受容体結合能:補充前後の検討

安田圭吾,武田則之,堀谷登美子,今井龍幸,山田浩司,林愼,後藤忍,青山かおり,三浦清,長井孝太郎,棚橋忍
日本内分泌学会雑誌 63(3), 239-246, 1987
… The effect of chronic glucocorticoid deficiency on insulin binding to erythrocyte was evaluated in 2 cases of ACTH deficiency, 2 of Sheehan's syndrome and a case of Addison's disease before and after the replacement therapy with cortisone acetate. … 75 gram oral glucose tolerance test (OGTT) was also performed. …
NAID 130001937482

妊娠と糖尿

水谷不二夫
日本産科婦人科學會雜誌 19(12), 1435-1442, 1967-12-01
… 妊娠時の糖質代謝について検索するため, まず妊婦に Glucose Tolerance Test (G.T.T.), Cortisone Glucose Tolerance Test (C.G.T.T.) を行なったところ, 一般に妊婦においては空腹時血糖は妊娠後期に低く, 耐糖能は軽度障害されておりこれら耐糖能異常群のうちいわゆる糖尿病群においては妊娠中毒症の発生, 巨大児を分 …
NAID 110002125486

実験的ステロイド糖尿病の研究:第一編実験的ステロイド糖尿病における食餌因子と蛋白同化ステロイド (Oxymetholone-HMD) の影響

宮城健
日本内分泌学会雑誌 40(11), 1448-1461,1414, 1965
… It is well known that adrenal corticosteroids have many biological effects on the carbohydrate metabolism.<BR>However, the mechanism of corticosteroids on carbohydrate metabolism has not been completely clarified and remains to be studied.<BR>In the present investigation, it was intended to study the effects of dietary carbohydrates on the experimental steroid diabetes induced by Ingles method in which 10 mg of cortisone was administered to rats daily. …
NAID 130001926041