- 日
- 関
WordNet
- executed with proper legal authority; "a binding contract"
- the protective covering on the front, back, and spine of a book; "the book had a leather binding" (同)book binding, cover, back
- strip sewn over or along an edge for reinforcement or decoration
- the capacity to attract and hold something
- a steroid hormone produced by the adrenal cortex or synthesized; administered as drugs they reduce swelling and decrease the bodys immune response; "adrenal cortical steroids are used to treat many different conditions" (同)corticoid, adrenal cortical steroid
- a family of proteins found in blood and milk and muscle and in plant seed
PrepTutorEJDIC
- 義務的な,拘束力ある / 〈U〉しばること;〈C〉しばる物 / 〈C〉製本,装丁 / 〈U〉縁(‘ふち')取り材料
- グロブリン(動植物組織内の純蛋白(たんぱく)質の総称)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/10/14 23:32:47」(JST)
[Wiki en表示]
| SERPINA6 |
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| Available structures |
| PDB |
Ortholog search: PDBe RCSB |
| List of PDB id codes |
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2VDX, 2VDY, 4BB2, 4C41, 4C49
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| Identifiers |
| Aliases |
SERPINA6, CBG, serpin family A member 6 |
| External IDs |
OMIM: 122500 MGI: 88278 HomoloGene: 20417 GeneCards: 866 |
| Gene ontology |
| Molecular function |
• steroid binding
• serine-type endopeptidase inhibitor activity
• lipid binding
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| Cellular component |
• extracellular space
• extracellular region
• extracellular exosome
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| Biological process |
• transport
• glucocorticoid metabolic process
• negative regulation of endopeptidase activity
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| Sources:Amigo / QuickGO |
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| RNA expression pattern |
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| More reference expression data |
| Orthologs |
| Species |
Human |
Mouse |
| Entrez |
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| Ensembl |
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| UniProt |
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| RefSeq (mRNA) |
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| RefSeq (protein) |
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| Location (UCSC) |
Chr 14: 94.3 – 94.32 Mb |
Chr 12: 103.65 – 103.66 Mb |
| PubMed search |
[1] |
[2] |
| Wikidata |
| View/Edit Human |
View/Edit Mouse |
Transcortin, also known as corticosteroid-binding globulin (CBG) or serpin A6 is a protein that in humans is encoded by the SERPINA6 gene. It is an alpha-globulin.[3][4][5]
Contents
- 1 Function
- 2 Binding
- 3 Synthesis
- 4 Clinical significance
- 5 See also
- 6 References
- 7 Further reading
- 8 External links
Function
This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucocorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors (serpins) which have evolved by duplication events.[5]
Binding
Transcortin binds several steroid hormones at high rates:
- Cortisol - Approximately 75% of the cortisol in circulation is bound to transcortin. (The rest is bound to serum albumin.) Cortisol is thought to be biologically active only when it is not bound to transcortin.[citation needed]
- Cortisone[6]
- Deoxycorticosterone (DOC)[6]
- Corticosterone - About 78% of serum corticosterone is bound to transcortin.
- Aldosterone - Approximately 17% of serum aldosterone is bound to transcortin, while another 47% is bound to serum albumin. The remaining 36% is free.[7]
- Progesterone - Approximately 18% of serum progesterone is bound to transcortin, while another 80% of it is bound to serum albumin. The remaining 2% is free.[8]
- 17-Hydroxyprogesterone[6]
In addition, approximately 4% of serum testosterone is bound to transcortin.[9] A similarly small fraction of serum estradiol is bound to transcortin as well.[citation needed]
Synthesis
Transcortin is produced by the liver and is increased by estrogens.[10]
Clinical significance
Mutations in this gene are rare. Only four mutations have been described, often in association with fatigue and chronic pain.[11] This mechanism for these symptoms is not known. This condition must be distinguished from secondary hypocortisolism. Exogenous hydrocortisone does not appear to improve the fatigue.
Hepatic synthesis of corticosteroid-binding globulin more than doubles in pregnancy; that is, unbound plasma cortisol in term pregnancy is approximately 2.5 times that of nonpregnant women.[12]
See also
- Serpin
- Circaseptan, 7-day biological cycle
References
- ^ "Human PubMed Reference:".
- ^ "Mouse PubMed Reference:".
- ^ Hammond GL, Smith CL, Goping IS, Underhill DA, Harley MJ, Reventos J, Musto NA, Gunsalus GL, Bardin CW (Aug 1987). "Primary structure of human corticosteroid binding globulin, deduced from hepatic and pulmonary cDNAs, exhibits homology with serine protease inhibitors". Proc Natl Acad Sci U S A. 84 (15): 5153–7. doi:10.1073/pnas.84.15.5153. PMC 298812. PMID 3299377.
- ^ Byth BC, Billingsley GD, Cox DW (Jul 1994). "Physical and genetic mapping of the serpin gene cluster at 14q32.1: allelic association and a unique haplotype associated with alpha 1-antitrypsin deficiency". Am J Hum Genet. 55 (1): 126–33. PMC 1918218. PMID 7912884.
- ^ a b "Entrez Gene: SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6".
- ^ a b c E. Edward Bittar; Neville Bittar (1997). Molecular and Cellular Endocrinology. Elsevier. p. 238. ISBN 978-1-55938-815-3. Retrieved 23 August 2012.
- ^ Principles and Practice of Endocrinology and Metabolism. Lippincott Williams & Wilkins. 24 April 2001. p. 712. ISBN 978-0-7817-1750-2. Retrieved 23 August 2012.
- ^ Negi (2009). Introduction To Endocrinology. PHI Learning Pvt. Ltd. p. 268. ISBN 978-81-203-3850-0. Retrieved 23 August 2012.
- ^ Dunn JF, Nisula BC, Rodbard D (July 1981). "Transport of steroid hormones: binding of 21 endogenous steroids to both testosterone-binding globulin and corticosteroid-binding globulin in human plasma". The Journal of Clinical Endocrinology and Metabolism. 53 (1): 58–68. doi:10.1210/jcem-53-1-58. PMID 7195404.
- ^ Musa BU, Seal US, Doe RP (September 1965). "Elevation of certain plasma proteins in man following estrogen administration: a dose-response relationship". J. Clin. Endocrinol. Metab. 25 (9): 1163–6. doi:10.1210/jcem-25-9-1163. PMID 4284083.
- ^ Torpy DJ, Lundgren BA, Ho JT, Lewis JG, Scott HS, Mericq V (January 2012). "CBG Santiago: a novel CBG mutation". J. Clin. Endocrinol. Metab. 97 (1): E151–5. doi:10.1210/jc.2011-2022. PMID 22013108.
- ^ Rosen MI, Shnider SM, Levinson G, Hughes (2002). Shnider and Levinson's anesthesia for obstetrics. Hagerstwon, MD: Lippincott Williams & Wilkins. p. 13. ISBN 0-683-30665-0.
Further reading
- Rosner W, Beers PC, Awan T, Khan MS (1976). "Identification of corticosteroid-binding globulin in human milk: measurement with a filter disk assay.". J. Clin. Endocrinol. Metab. 42 (6): 1064–73. doi:10.1210/jcem-42-6-1064. PMID 932172.
- Smith CL, Power SG, Hammond GL (1992). "A Leu----His substitution at residue 93 in human corticosteroid binding globulin results in reduced affinity for cortisol.". J. Steroid Biochem. Mol. Biol. 42 (7): 671–6. doi:10.1016/0960-0760(92)90107-T. PMID 1504007.
- Brotherton J (1990). "Cortisol and transcortin in human seminal plasma and amniotic fluid as estimated by modern specific assays.". Andrologia. 22 (3): 197–204. doi:10.1111/j.1439-0272.1990.tb01966.x. PMID 2240617.
- Seralini GE, Bérubé D, Gagné R, Hammond GL (1991). "The human corticosteroid binding globulin gene is located on chromosome 14q31-q32.1 near two other serine protease inhibitor genes.". Hum. Genet. 86 (1): 73–5. doi:10.1007/bf00205177. PMID 2253941.
- Underhill DA, Hammond GL (1990). "Organization of the human corticosteroid binding globulin gene and analysis of its 5'-flanking region.". Mol. Endocrinol. 3 (9): 1448–54. doi:10.1210/mend-3-9-1448. PMID 2608068.
- Loric S, Egloff M, Domingo M, et al. (1990). "Immunochemical characterization of corticosteroid-binding globulin in human bronchoalveolar fluid.". Clin. Chim. Acta. 186 (1): 19–23. doi:10.1016/0009-8981(89)90198-8. PMID 2612005.
- Heubner A, Belovsky O, Müller W, et al. (1987). "Application of liquid-liquid partition chromatography in the simultaneous purification of sex-hormone-binding globulin and corticosteroid-binding globulin.". J. Chromatogr. 397: 419–34. doi:10.1016/S0021-9673(01)85027-5. PMID 2821037.
- Kato EA, Hsu BR, Kuhn RW (1988). "Comparative structural analyses of corticosteroid binding globulin.". J. Steroid Biochem. 29 (2): 213–20. doi:10.1016/0022-4731(88)90268-3. PMID 3347061.
- Bardin CW, Gunsalus GL, Musto NA, et al. (1988). "Corticosteroid binding globulin, testosterone-estradiol binding globulin, and androgen binding protein belong to protein families distinct from steroid receptors.". J. Steroid Biochem. 30 (1-6): 131–9. doi:10.1016/0022-4731(88)90085-4. PMID 3386241.
- Hammond GL, Langley MS (1986). "Identification and measurement of sex hormone binding globulin (SHBG) and corticosteroid binding globulin (CBG) in human saliva.". Acta Endocrinol. 112 (4): 603–8. doi:10.1530/acta.0.1120603. PMID 3751467.
- Agrimonti F, Frairia R, Fornaro D, et al. (1983). "Circadian and circaseptan rhythmicities in corticosteroid-binding globulin (CBG) binding activity of human milk.". Chronobiologia. 9 (3): 281–90. PMID 7172869.
- Misao R, Hori M, Ichigo S, et al. (1995). "Levels of sex hormone-binding globulin (SHBG) and corticosteroid-binding globulin (CBG) messenger ribonucleic acid (mRNAs) in ovarian endometriosis.". Reprod. Nutr. Dev. 35 (2): 155–65. doi:10.1051/rnd:19950204. PMID 7734053.
- Misao R, Hori M, Ichigo S, et al. (1995). "Corticosteroid-binding globulin mRNA levels in human uterine endometrium.". Steroids. 59 (10): 603–7. doi:10.1016/0039-128X(94)90055-8. PMID 7878688.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene. 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Avvakumov GV, Hammond GL (1994). "Glycosylation of human corticosteroid-binding globulin. Differential processing and significance of carbohydrate chains at individual sites.". Biochemistry. 33 (19): 5759–65. doi:10.1021/bi00185a012. PMID 8180202.
- Van Baelen H, Power SG, Hammond GL (1993). "Decreased cortisol-binding affinity of transcortin Leuven is associated with an amino acid substitution at residue-93.". Steroids. 58 (6): 275–7. doi:10.1016/0039-128X(93)90072-U. PMID 8212073.
- Misao R, Nakanishi Y, Fujimoto J, et al. (1996). "Expression of corticosteroid-binding globulin mRNA in human uterine endometrial cancers.". Steroids. 60 (10): 720–4. doi:10.1016/0039-128X(95)00106-Z. PMID 8539782.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene. 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
External links
- Transcortin at the US National Library of Medicine Medical Subject Headings (MeSH)
- The MEROPS online database for peptidases and their inhibitors: I04.954
- SERPINA6 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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Proteins: carrier proteins
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| Fatty acid |
- FABP1
- FABP2
- FABP3
- FABP4
- FABP5
- FABP6
- FABP7
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| Hormone |
- peptide hormone: Follistatin
- Growth hormone binding protein
- Insulin-like growth factor binding protein
- IGFBP1
- IGFBP2
- IGFBP3
- IGFBP4
- IGFBP5
- IGFBP6
- IGFBP7
- Neurophysins
- steroid hormone: Sex hormone binding globulin/Androgen binding protein
- Transcortin
- Thyroxine-binding globulin
- Transthyretin
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| Metal/element |
- calcium
- Calcium-binding protein
- Calmodulin-binding proteins
- copper
- iron
- Iron-binding proteins
- Transferrin receptor
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| Vitamin |
- Retinol binding protein
- Transcobalamin
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| Pigment |
- Plant Light-Harvesting Complex
- Orange Carotenoid Protein
- Phycobiliprotein
- Photosynthetic Reaction Centers
- Phytochrome
- Rhodopsin
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| Other |
- Acyl carrier protein
- Adaptor protein
- Cholesterylester transfer protein
- F-box protein
- GTP-binding protein
- Latent TGF-beta binding protein
- Major urinary proteins
- Membrane transport protein
- Odorant binding protein
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Proteins: Globular proteins
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| Serum globulins |
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Alpha globulins
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serpins:
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- alpha-1 (Alpha 1-antichymotrypsin, Alpha 1-antitrypsin)
- alpha-2 (Alpha 2-antiplasmin)
- Antithrombin (Heparin cofactor II)
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carrier proteins:
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- alpha-1 (Transcortin)
- alpha-2 (Ceruloplasmin)
- Retinol binding protein
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other:
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- alpha-1 (Orosomucoid)
- alpha-2 (alpha-2-Macroglobulin, Haptoglobin)
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Beta globulins
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carrier proteins:
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- Sex hormone-binding globulin
- Transferrin
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other:
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- Angiostatin
- Hemopexin
- Beta-2 microglobulin
- Factor H
- Plasminogen
- Properdin
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Gamma globulin
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Other
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- Fibronectin (fFN: Fetal fibronectin)
- Macroglobulin/Microglobulin
- Transcobalamin
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| Other globulins |
- Beta-lactoglobulin
- Thyroglobulin
- Alpha-lactalbumin
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| Albumins |
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Egg white
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- Conalbumin
- Ovalbumin
- Avidin
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Serum albumin
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- Human serum albumin
- Bovine serum albumin
- Prealbumin
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Other
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- C-reactive protein
- Lactalbumin (Alpha-lactalbumin)
- Parvalbumin
- Ricin
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- see also disorders of globin and globulin proteins
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Serpins
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| inhibitory |
- Alpha 1-antichymotrypsin
- Alpha 1-antitrypsin
- Alpha 2-antiplasmin
- Antithrombin
- C1-inhibitor
- Heparin cofactor II
- Protein C inhibitor
- Plasminogen activator inhibitor-1
- Plasminogen activator inhibitor-2
- Protein Z-related protease inhibitor
- SERPINA1
- SERPINA2
- SERPINA3
- SERPINA4
- SERPINA5
- SERPINA6
- SERPINA7
- SERPINA8
- SERPINA9
- SERPINA14
- SERPINB1
- SERPINB2
- SERPINB3
- SERPINB4
- SERPINB5
- SERPINB6
- SERPINB7
- SERPINB8
- SERPINB9
- SERPINB13
- SERPINC1
- SERPIND1
- SERPINE1
- SERPINE2
- SERPINE2
- SERPINF1
- SERPING1
- SERPINH1
- SERPINI1
- SERPINI2
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| Cross class inhibitory |
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| noninhibitory |
- Heat shock protein 47
- Maspin
- Ovalbumin
- SERPINF1
- Thyroxine-binding globulin
- Transcortin
- SERPINF1
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see also disorders of globin and globulin proteins
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Protein, glycoconjugate: glycoproteins and glycopeptides
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| Mucoproteins |
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Mucin
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- CD43
- CD164
- MUC1
- MUC2
- MUC3A
- MUC3B
- MUC4
- MUC5AC
- MUC5B
- MUC6
- MUC7
- MUC8
- MUC12
- MUC13
- MUC15
- MUC16
- MUC17
- MUC19
- MUC20
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Other
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- Haptoglobin
- Intrinsic factor
- Orosomucoid
- Peptidoglycan
- Phytohaemagglutinin
- Ovomucin
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| Proteoglycans |
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CS/DS
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- Decorin
- Biglycan
- Versican
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HS/CS
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CS
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- Chondroitin sulfate proteoglycans: Aggrecan
- Neurocan
- Brevican
- CD44
- CSPG4
- CSPG5
- Platelet factor 4
- Structural maintenance of chromosomes 3
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KS
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- Fibromodulin
- Lumican
- Keratocan
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HS
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| Other |
- Activin and inhibin
- ADAM
- Alpha 1-antichymotrypsin
- Apolipoprotein H
- CD70
- Asialoglycoprotein
- Avidin
- B-cell activating factor
- 4-1BB ligand
- Cholesterylester transfer protein
- Clusterin
- Colony-stimulating factor
- Hemopexin
- Lactoferrin
- Membrane glycoproteins
- Myelin protein zero
- Osteonectin
- Protein C
- Protein S
- Serum amyloid P component
- Sialoglycoprotein
- CD43
- Glycophorin
- Glycophorin C
- Thrombopoietin
- Thyroglobulin
- Thyroxine-binding proteins
- Transcortin
- Tumor necrosis factor alpha
- Uteroglobin
- Vitronectin
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Glucocorticoid receptor modulators
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| GR |
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Agonists
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Mixed (SEGRAs)
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- Dagrocorat
- Fosdagrocorat
- Mapracorat
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Antagonists
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- 3α-Hydroxytibolone
- 3β-Hydroxytibolone
- 17α-Methylprogesterone
- Aglepristone
- Asoprisnil
- C108297
- C113176
- CORT-108297
- Cyproterone acetate
- Formebolone
- Guggulsterone
- Ketoconazole
- Lilopristone
- LLY-2707
- Miconazole
- Mifepristone
- Onapristone
- ORG-34116
- ORG-34517 (SCH-900636)
- ORG-34850
- Pregnenolone 16α-carbonitrile
- Telapristone
- Tibolone
- Toripristone
- Ulipristal acetate
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See also: Androgenics • Estrogenics • Mineralocorticoidics • Progestogenics • Steroid hormone metabolism modulators
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Mineralocorticoid receptor modulators
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| MR |
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Agonists
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- 11-Deoxycorticosterone (desoxycortone)
- 11-Deoxycortisol (cortodoxone)
- 16α,18-Dihydroxy-11-deoxycorticosterone
- 17α-Hydroxyaldosterone
- 18-Hydroxy-11-deoxycorticosterone
- 19-Norprogesterone
- Aldosterone
- Corticosterone
- Desoxycortone acetate
- Desoxycortone enanthate
- Desoxycortone glucoside
- Desoxycortone pivalate
- Hydrocortisone (cortisol)
- Fludrocortisone
- Fludrocortisone acetate
- Mometasone furoate
- Prednisolone
- Prednisone
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Antagonists
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- Steroidal: 3α-Hydroxytibolone
- 3β-Hydroxytibolone
- 6β-Hydroxy-7α-thiomethylspironolactone
- 7α-Thiomethylspironolactone
- 17α-Hydroxyprogesterone
- 18-Deoxyaldosterone
- Canrenoate potassium (potassium canrenoate)
- Canrenoic acid
- Canrenone
- Dicirenone
- Dimethisterone
- Drospirenone
- Dydrogesterone
- Eplerenone
- Gestodene
- Guggulsterone
- Medrogestone
- Mespirenone
- Mexrenoate potassium
- Mexrenoic acid
- Mexrenone
- Oxprenoic acid
- Oxprenoate potassium (RU-28318)
- Pregnenolone
- Progesterone
- Prorenoate potassium
- Prorenoic acid (prorenoate)
- Prorenone
- RO-14-9012
- RU-26752
- SC-5233
- SC-8109
- SC-11927
- SC-19886
- SC-24813
- SC-25152
- SC-26519
- SC-27169
- Spirorenone
- Spironolactone
- Spiroxasone
- Tibolone
- Trimegestone
- ZK-91587
- ZK-97894
- Non-steroidal: Amlodipine
- Apararenone
- Benidipine
- BR-4628
- Esaxerenone
- Felodipine
- Finerenone
- Nifedipine
- Nimodipine
- Nitrendipine
- PF-03882845
- SM-368229
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See also: Androgenics • Estrogenics • Glucocorticoidics • Progestogenics • Steroid hormone metabolism modulators
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Progesterone receptor modulators
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| PR |
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Agonists
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Mixed (SPRMs)
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- Apigenin
- Asoprisnil
- Asoprisnil ecamate
- Guggulsterone
- Kaempferol
- J1042
- LG-120838
- Naringenin
- PRA-910
- Syringic acid
- Telapristone
- Antagonistic: Mifepristone
- Org-31710
- Org-33628
- Ulipristal acetate
- ZK-137316
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|
|
Antagonists
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- 3α-Hydroxytibolone
- 3β-Hydroxytibolone
- Aglepristone
- Lilopristone
- Lonaprisan
- Onapristone
- Toripristone
- Valproic acid
- Vilaprisan
- Zanoterone
- ZM-150271
- ZM-172406
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|
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mPRs
(PAQRs) |
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Agonists
|
- 5α-Dihydroprogesterone
- 5β-Dihydroprogesterone
- 11-Deoxycorticosterone
- 17α-Hydroxyprogesterone
- 17α,21-Dihydroxyprogesterone
- 21-Hydroxyprogesterone
- Allopregnanolone
- Mifepristone
- Pregnenolone
- Progesterone
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|
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Antagonists
|
|
|
|
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See also: Androgenics • Estrogenics • Glucocorticoidics • Mineralocorticoidics • Steroid hormone metabolism modulators
|
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Assessment of adrenal function in patients with acute hepatitis using serum free and total cortisol.
- Degand T1, Monnet E1, Durand F2, Grandclement E3, Ichai P4, Borot S5, Qualls CR6, Agin A7, Louvet A8, Dumortier J9, Francoz C2, Dumoulin G3, Di Martino V1, Dorin R10, Thevenot T11.
- Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.Dig Liver Dis.2015 Sep;47(9):783-9. doi: 10.1016/j.dld.2015.05.016. Epub 2015 May 22.
- BACKGROUND: Adrenal dysfunction is frequently reported in severe acute hepatitis using serum total cortisol.AIMS: Because 90% of serum cortisol is bound to proteins that are altered during stress, we investigated the effect of decreased cortisol-binding proteins on serum total and free cortisol in s
- PMID 26077885
- The cortisol response to ACTH in pigs, heritability and influence of corticosteroid-binding globulin.
- Larzul C1, Terenina E2, Foury A3, Billon Y4, Louveau I5, Merlot E5, Mormede P2.
- Animal : an international journal of animal bioscience.Animal.2015 Aug 24:1-6. [Epub ahead of print]
- In the search for biological basis of robustness, this study aimed (i) at the determination of the heritability of the cortisol response to ACTH in juvenile pigs, using restricted maximum likelihood methodology applied to a multiple trait animal model, and (ii) at the study of the relationships betw
- PMID 26302113
- Three calculations of free cortisol versus measured values in the critically ill.
- Molenaar N1, Groeneveld AB2, de Jong MF3.
- Clinical biochemistry.Clin Biochem.2015 Jul 10. pii: S0009-9120(15)00275-1. doi: 10.1016/j.clinbiochem.2015.07.014. [Epub ahead of print]
- OBJECTIVES: To investigate the agreement between the calculated free cortisol levels according to widely applied Coolens and adjusted Södergård equations with measured levels in the critically ill.DESIGN AND METHODS: A prospective study in a mixed intensive care unit. We consecutively included 103
- PMID 26169244
Japanese Journal
- コルチコステロイド結合蛋白(CBG) (広範囲 血液・尿化学検査 免疫学的検査(第7版・4)その数値をどう読むか) -- (内分泌学的検査 副腎皮質関係)
- ヒト胎盤における Corticosteroid-Binding Globulin の発現
- Stress in the Racing Horse : Coping vs Not Coping
- Alexander Susan,Irvine C.H.G
- Journal of equine science 9(3), 77-81, 1998-09-00
- NAID 10006140515
Related Links
- This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucocorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing ...
Related Pictures
★リンクテーブル★
[★]
- 同
- corticosteroid binding globulin
- 関
- See Corticosteroid-binding globulin
- 関
- cortisol binding globulin
[★]
- 同
- CBG／ transcortin
- 同
- CBG
[★]
- 関
- affinity、associate、bind、bond、bonding、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、connective、connectivity、couple、dock、engage、engagement、join、ligate、linkage、symphysial、symphysic、union
[★]
コルチコイド
- 関
- glucocorticoid, glucocorticoids
[★]
- 関
- globule、globulus、spherule
