WordNet

bring disorder to (同)disarray
a physical condition in which there is a disturbance of normal functioning; "the doctor prescribed some medicine for the disorder"; "everyone gets stomach upsets from time to time" (同)upset
a disturbance of the peace or of public order
coat with a layer of copper
a ductile malleable reddish-brown corrosion-resistant diamagnetic metallic element; occurs in various minerals but is the only metal that occurs abundantly in large masses; used as an electrical and thermal conductor (同)Cu, atomic number 29
a copper penny
a reddish-brown color resembling the color of polished copper (同)copper color
any of various small butterflies of the family Lycaenidae having coppery wings
the organic processes (in a cell or organism) that are necessary for life (同)metabolic_process
not arranged in order (同)unordered

PrepTutorEJDIC

〈U〉『無秩序』,混乱,乱雑(confusion) / 《しばしば複数形で》(社会的・政治的な)粉争,騒動 / 〈C〉(肉体的・精神的な)不調,異常,障害 / …‘の'秩序を乱す / 〈心身〉‘に'異常を起こさせる
〈U〉『銅』(化学記号は『Cu』) / 〈C〉《英話》銅貨 / 〈C〉銅製品,銅器;《英》(先濯用)銅の大がま / 〈U〉赤銅色 / 銅[製]の / 赤銅色の / …‘に'をかぶせる,銅板を張る
ポリ公
新陳代謝,物質交代

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1. 銅欠乏性脊髄神経障害 copper deficiency myeloneuropathy
2. 食物中の微量ミネラルの概要 overview of dietary trace minerals
3. 先天性代謝異常：代謝性救急疾患 inborn errors of metabolism metabolic emergencies
4. ウィルソン病：疫学および病因 wilson disease epidemiology and pathogenesis
5. 女性における双極性障害：避妊、妊娠前評価およびカウンセリング bipolar disorder in women contraception and preconception assessment and counseling

Amann VC, Maru NK, Jain V.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.J Clin Sleep Med.2015 Apr 7. pii: jc-00453-14. [Epub ahead of print]
ABSTRACT: Wilson disease (WD) is an autosomal recessive disorder of copper metabolism resulting in copper accumulation in a number of organs including the liver, brain, and cornea, predominantly leading to hepatic, neurologic, and psychiatric manifestations. An association between WD and sleep probl
PMID 25902827

Correlation between conjunctival and corneal calcification and cardiovascular calcification in patients undergoing maintenance hemodialysis.

Sun W1, Sun M, Zhang M, Liu Y, Lin X, Zhao S, Ma L.
Hemodialysis international. International Symposium on Home Hemodialysis.Hemodial Int.2015 Apr;19(2):270-8. doi: 10.1111/hdi.12236. Epub 2014 Nov 6.
The purpose of this study was to investigate the correlation of conjunctival and corneal calcification (CCC) with cardiovascular calcification in patients undergoing maintenance hemodialysis (MHD). A total of 122 patients undergoing MHD in our hospital were included in this study. Conjunctival and c
PMID 25377787

Van Biervliet S1, Küry S, De Bruyne R, Vanakker OM, Schmitt S, Vande Velde S, Blouin E, Bézieau S.
Journal of pediatric gastroenterology and nutrition.J Pediatr Gastroenterol Nutr.2015 Apr;60(4):457-9. doi: 10.1097/MPG.0000000000000628.
Wilson disease is a rare autosomal recessive disorder of the copper metabolism caused by homozygous or compound heterozygous mutations in the ATP-ase Cu(2+) transporting polypeptide (ATP7B) gene. The copper accumulation in different organs leads to the suspicion of Wilson disease. We describe a chil
PMID 25825851

Excess Copper Chelating Therapy for Wilson Disease Induces Anemia and Liver Dysfunction

, , , , , , , ,
Internal Medicine 50(14), 1461-1464, 2011
… Wilson disease is a genetic disorder characterized by accumulation of copper in the body. … Excess copper is toxic, but copper is an essential trace element. … Copper-binding ceruloplasmin is important for iron metabolism. … Excess copper chelating treatment-induced anemia and iron deposition in the liver was suspected. …
NAID 130000969422

柳澤裕之,小岩井利一
総合健診 = Health evaluation and promotion 36(6), 456-460, 2009-11-10
… Zinc, copper, iron and chromium are essential trace elements. … It is most likely that the deficiency of zinc, copper, iron and chromium is associated with life - style related diseases and aging. … Actually, an increase in free radicals, a decrease in immunocompetence, an increase in blood pressure, the disorder of lipid metabolism, a reduction in glucose tolerance and a rise in carcinogenesis etc. …
NAID 10026308594

Children's toxicology from bench to bed - Liver Injury (3) : Oxidative stress and anti-oxidant systems in liver of patients with wilson disease

, ,
Journal of toxicological sciences 34(Special Issue II), SP229-SP236, 2009-07
… The role of oxidative stress in the pathogenesis of liver disease in Wilson disease (WD), a genetic disorder characterized by excess hepatic deposition of copper, which generates free radicals, remains unclear. … These results suggest that excessive copper-derived oxidants contribute to development and progression of liver disease in WD. …
NAID 110007337716