WordNet
- a small tube
PrepTutorEJDIC
- 小管,細管
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/26 23:06:08」(JST)
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Connecting tubule |
Scheme of renal tubule and its vascular supply.
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Details |
Latin |
tubulus renalis arcuatus |
Precursor |
Metanephric blastema |
Identifiers |
Gray's |
p.1223 |
Dorlands
/Elsevier |
t_22/12830099 |
Anatomical terminology |
In the kidney, the connecting tubule (CNT, or junctional tubule, or arcuate renal tubule) is a tubular segment of the renal collecting duct system that connects the distal convoluted tubule to the cortical collecting duct.
Contents
- 1 Structure
- 2 Function
- 3 References
- 4 External links
Structure
Many sources include the connecting tubule as part of the collecting duct system. However, the embryological origin is more similar to the nephron than it is to the rest of the collecting duct (which derives from the ureteric bud), and other sources therefore classify the connecting tubule with the nephron.
Some connecting tubules, usually associated with juxtamedullary nephrons, arch upwards before reaching the cortical collecting ducts. It is this "arcuate" feature which gives the tubule its alternate name.
Function
It participates in the regulation of water and electrolytes, including sodium, and chloride.
The CNT is sensitive to both isoprotenerol (more so than the cortical collecting ducts) and antidiuretic hormone (less so than the cortical collecting ducts), the latter largely determining its function in water reabsorption.
References
- Eaton, Douglas C., Pooler, John P. (2004). Vander's Renal Physiology (6th ed.). Lange Medical Books/McGraw-Hill. ISBN 0-07-135728-9.
- Imai M (1979). "The connecting tubule: a functional subdivision of the rabbit distal nephron segments". Kidney Int 15 (4): 346–56. doi:10.1038/ki.1979.46. PMID 513494.
External links
- Physiology: 7/7ch03/7ch03p18 - Essentials of Human Physiology
- Types of tubules at ndif.org
- Diagram (#31) at benet.org
Anatomy of the urinary system
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Kidneys |
Layers
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- Fascia
- Capsule
- Cortex
- Medulla
- sinus
- pyramids
- medullary interstitium
- Lobe
- Cortical lobule
- Medullary ray
- Nephron
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Circulation
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- Arteries
- Renal artery
- segmental
- interloblar
- arcuate
- interlobular
- afferent
- Veins
- Renal vein
- Peritubular capillaries
- Vasa recta
- arcuate
- interlobar
- efferent
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Nephron
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Renal corpuscle
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- Glomerulus
- Bowman's capsule
- Glomerular basement membrane
- Podocyte
- Filtration slits
- Mesangium
- Intraglomerular mesangial cell
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Renal tubule
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- Proximal convoluted tubule
- Loop of Henle
- Descending
- Thin ascending
- Thick ascending
- Distal convoluted tubule
- Connecting tubule
- Tubular fluid
- Renal papilla
- Minor calyx
- Major calyx
- Renal pelvis
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Juxtaglomerular apparatus
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- Macula densa
- Juxtaglomerular cells
- Mesangium
- Extraglomerular mesangial cell
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Ureters |
- Orifice of ureter
- Ureteropelvic junction
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Bladder |
- Apex
- Uvula
- Neck
- Median umbilical ligament
- Muscular layer
- Mucosa
- Submucosa
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Urethra |
- Urethral sphincters
- External sphincter
- Internal sphincter
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Index of the urinary system
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Description |
- Anatomy
- Physiology
- Development
- Cells
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Disease |
- Electrolyte and acid-base
- Congenital
- Neoplasms and cancer
- Other
- Symptoms and signs
- Urine tests
- Blood tests
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Treatment |
- Procedures
- Drugs
- Intravenous fluids
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UpToDate Contents
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English Journal
- Effect of salt intake on afferent arteriolar dilatation: Role of connecting tubule glomerular feedback (CTGF).
- Wang H1, Romero CA1, Masjoan Juncos JX2, Monu SR1, Peterson EL3, Carretero OA4.
- American journal of physiology. Renal physiology.Am J Physiol Renal Physiol.2017 Aug 23:ajprenal.00320.2017. doi: 10.1152/ajprenal.00320.2017. [Epub ahead of print]
- PMID 28835421
- Adaptive changes in GFR, tubular morphology, and transport in subtotal nephrectomized kidneys: modeling and analysis.
- Layton AT1, Edwards A2,3, Vallon V4,5.
- American journal of physiology. Renal physiology.Am J Physiol Renal Physiol.2017 Aug 1;313(2):F199-F209. doi: 10.1152/ajprenal.00018.2017. Epub 2017 Mar 22.
- PMID 28331059
- Renal Tubular Ubiquitin-Protein Ligase NEDD4-2 Is Required for Renal Adaptation during Long-Term Potassium Depletion.
- Al-Qusairi L1,2, Basquin D1,2, Roy A3, Rajaram RD1,2, Maillard MP4, Subramanya AR5, Staub O6,2.
- Journal of the American Society of Nephrology : JASN.J Am Soc Nephrol.2017 Aug;28(8):2431-2442. doi: 10.1681/ASN.2016070732. Epub 2017 Mar 13.
- PMID 28289184
Japanese Journal
- Nephron Distribution of Total Low Km Cyclic AMP Phosphodiesterase in Mouse, Rat and Rabbit Kidney.
- Kusano Eiji,Yoshida Izumi,Takeda Shigeyuki,Homma Sumiko,Yusufi Ahad N.K.,Dousa Thomas P.,Asano Yasushi
- The Tohoku Journal of Experimental Medicine 193(3), 207-220, 2001
- … We assayed total low Km cAMP PDE in microdissected tubule segments, using 10−6 M (3H)-cAMP as a substrate. … Proximal convoluted tubule, proximal straight tubule, medullary thick ascending limb of Henle's loop (mTAL), and outer medullary collecting duct (OMCD) had intermediated activity. … Greater cAMP PDE activity was detected in cortical ascending limb of Henle's loop (cTAL), cortical collecting duct and in distal convoluted tubule (DCT). …
- NAID 130004459103
- Flow-dependent activation of maxi K^+ channels in apical membrane of rabbit connecting tubule
Related Links
- con·nect·ing tu·bule a narrow arching tubule of the kidney joining the distal convoluted tubule and the collecting tubule. ... Disclaimer All content on this website, including dictionary, thesaurus, literature, geography, and other ...
- tu·bule (to o′byo ol, tyo o′-) n. A very small tube or tubular structure. [Latin tubulus, diminutive of tubus, tube.] tubule (ˈtjuːbjuːl) n 1. (Anatomy) any small tubular structure, esp one in an animal, as in the kidney, testis, etc [C17: from ...
Related Pictures
★リンクテーブル★
[★]
- 英
- connecting tubule CNT
- 関
- ヘンレループ、尿細管
[★]
- 関
- canaliculi、canaliculus、kidney tubule、renal tubular、renal tubule、tubular、uriniferous tubule
[★]
コネクチン
- 関
- titin