conjugated hyperbilirubinemia

関

体質性黄疸

WordNet

1. undergo conjugation
2. unite chemically so that the product is easily broken down into the original compounds
3. formed by the union of two compounds; "a conjugated protein" (同)conjugated
4. of an organic compound; containing two or more double bonds each separated from the other by a single bond (同)conjugated
5. joined together especially in a pair or pairs (同)conjugated, coupled
6. (of a pinnate leaflet) having only one pair of leaflets
7. add inflections showing person, number, gender, tense, aspect, etc.; "conjugate the verb"
8. abnormally high amounts of bile pigment (bilirubin) in the blood

PrepTutorEJDIC

1. 〈動詞〉'を'活用(変化)させる / 〈動詞が〉活用(変化)する / 〈単細胞生物が〉接合する / (特に対になって)結合した,接合の

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• 1. Approach to the patient with abnormal liver biochemical and function tests
• 2. 黄疸または無症候性高ビリルビン血症の分類および原因 classification and causes of jaundice or asymptomatic hyperbilirubinemia
• 3. 抱合型高ビリルビン血症関連の遺伝性疾患 inherited disorders associated with conjugated hyperbilirubinemia
• 4. 新生児胆汁うっ滞に対するアプローチ approach to neonatal cholestasis
• 5. ビリルビン代謝 bilirubin metabolism

English Journal

• Cholestatic liver (dys)function during sepsis and other critical illnesses.

• Jenniskens M1, Langouche L1, Vanwijngaerden YM1, Mesotten D1, Van den Berghe G2.
• Intensive care medicine.Intensive Care Med.2016 Jan;42(1):16-27. doi: 10.1007/s00134-015-4054-0. Epub 2015 Sep 21.
• OBJECTIVE: In ICU patients, abnormal liver tests are common. Markers of cholestasis are associated with adverse outcome. Research has focused on the possibility that mild hyperbilirubinemia, instead of indicating inadvertent cholestasis, may be adaptive and beneficial. These new insights are reviewe
• PMID 26392257

• Impaired Hepatic Uptake by Organic Anion-Transporting Polypeptides Is Associated with Hyperbilirubinemia and Hypercholanemia in Atp11c Mutant Mice.

• Matsuzaka Y1, Hayashi H2, Kusuhara H1.
• Molecular pharmacology.Mol Pharmacol.2015 Dec;88(6):1085-92. doi: 10.1124/mol.115.100578. Epub 2015 Sep 23.
• Biliary excretion of organic anions, such as bile acids (BAs), is the main osmotic driving force for bile formation, and its impairment induces intrahepatic cholestasis. We investigated the involvement of Atp11c in the hepatic transport of organic anions using Atp11c mutant mice, which exhibit hyper
• PMID 26399598

• Inherited Disorders of Bilirubin Clearance.

• Memon N1, Weinberger BI2, Hegyi T1, Aleksunes LM3.
• Pediatric research.Pediatr Res.2015 Nov 23. doi: 10.1038/pr.2015.247. [Epub ahead of print]
• Inherited disorders of hyperbilirubinemia may be caused by increased bilirubin production or decreased bilirubin clearance. Reduced hepatic bilirubin clearance can be due to defective 1) unconjugated bilirubin uptake and intrahepatic storage, 2) conjugation of glucuronic acid to bilirubin (e.g. Gilb
• PMID 26595536

Japanese Journal

• Twice-weekly fluconazole prophylaxis in premature infants : Association with cholestasis

• BHAT Vishwanath,FOJAS Milliecor,SASLOW Judy G.,SHAH Sahil,SANNOH Sulaiman,AMENDOLIA Barbara,PYON Kee,KEMBLE Nicole,STAHL Gary,AGHAI Zubair H.
• Pediatrics international : official journal of the Japan Pediatric Society 53(4), 475-479, 2011-08-01
• NAID 10029558830

• 診療と研究 直接ビリルビン高値を呈した極低出生体重児の臨床像の解析

• 俣野 美雪,高橋 尚人,矢田 ゆかり [他]
• 小児科診療 73(7), 1232-1236, 2010-07
• NAID 40017179957

Related Links

• Conjugated Hyperbilirubinemia - Diseases & Conditions ...

Bilirubin is a tetrapyrrole created by the normal breakdown of heme. Most bilirubin is produced during the breakdown of hemoglobin and other hemoproteins. Accumulation of bilirubin or its conjugates in body tissues produces jaundice (ie, icterus), which is characterized by high plasma bilirubin levels ...

• Conjugated Hyperbilirubinemia

Physical Examination The first manifestation in cases of conjugated hyperbilirubinemia is commonly a brownish discoloration of the urine. Although scleral icterus may also be present, this typically reflects the unconjugated fraction of ...

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★リンクテーブル★

リンク元	「高直接ビリルビン血症」「直接型高ビリルビン血症」
拡張検索	「familial unconjugated hyperbilirubinemia」「unconjugated hyperbilirubinemia」
関連記事	「conjugate」「conjugated」「hyperbilirubinemia」

「高直接ビリルビン血症」

　　[★]

英

direct-reacting hyperbilirubinemia

同

抱合型高ビリルビン血症 conjugated hyperbilirubinemia

「直接型高ビリルビン血症」

　　[★]

英

conjugated hyperbilirubinemia

関

高直接ビリルビン血症

「familial unconjugated hyperbilirubinemia」

　　[★] 家族性非抱合型高ビリルビン血症

「unconjugated hyperbilirubinemia」

　　[★] 高非抱合型ビリルビン血症

「conjugate」

　　[★]

• n.

• 抱合体、接合体、複合物

• vt.

• (言語)(動詞)を活用/変化させる。
• (化学)～を共役させる。

• vi.

• (生物)接合する。(言語)動詞が活用/変化する。
• 抱合する、接合する、結合する、共役する

• adj.

関

associate、bind、binding、bond、bonding、combine、complex、conjoin、conjugated、conjugation、conjunction、connect、connection、couple、coupling、dock、engage、engagement、join、juncture、ligate、linkage、mating、symphysial、union、zygote、zygotic

　 　 　 　 　 　 　 　

「conjugated」

　　[★]

• adj.

• 抱合型の、複合化の、(化学)共役した

関

conjugate、conjugation、couple、coupling

「hyperbilirubinemia」

　　[★] 高ビリルビン血症