composite transposon

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WordNet

1. of or relating to or belonging to the plant family Compositae
2. considered the most highly evolved dicotyledonous plants, characterized by florets arranged in dense heads that resemble single flowers (同)composite plant
3. consisting of separate interconnected parts
4. a segment of DNA that can become integrated at many different sites along a chromosome (especially a segment of bacterial DNA that can be translocated as a whole) (同)jumping gene

PrepTutorEJDIC

1. 合成の,複合の / キク科の / 合成物,複合物 / キク科植物

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/03/20 13:27:35」(JST)

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A composite transposon is similar in function to simple transposons and Insertion Sequence (IS) elements in that it has protein coding DNA segments flanked by inverted, repeated sequences that can be recognized by transposase enzymes. A composite transposon, however, is flanked by two separate IS elements which may or may not be exact replicas. Instead of each IS element moving separately, the entire length of DNA spanning from one IS element to the other is transposed as one complete unit. Composite transposons will also often carry one or more genes conferring antibiotic resistance.

Composite Transposons flanked by SINEs in Mammalian Genomes

Two SINEs may act in concert to flank and mobilize an intervening single copy DNA sequence. This was reported for a 710 bp DNA sequence upstream of the bovine beta globin gene. The DNA arrangement forms a composite transposon whose presence has been confirmed by the complete bovine genomic sequence where the mobilized sequence may be found on bovine chromosome 15 in contig NW_001493315.1 nucleotides #1085432–1086142 and the originating sequence may be found on bovine chromosome 2 in contig NW_001501789.2 nucleotides #1096679–1097389. It is likely that similar composite transposons exist in other bovine genomic regions and other mammalian genomes. They could be detected with suitable algorithms.

See also

Tn10

References

UpToDate Contents

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English Journal

• Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.

• Karah N1, Dwibedi CK2, Sjöström K3, Edquist P3, Johansson A2, Wai SN4, Uhlin BE4.
• Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2016 Jan 11. pii: AAC.02143-15. [Epub ahead of print]
• Acinetobacter baumannii has emerged as an important opportunistic pathogen equipped with a growing number of antibiotic resistance genes. Our study investigated the molecular epidemiology and antibiotic resistance features of 28 consecutive carbapenem-resistant clinical isolates of A. baumannii coll
• PMID 26824943

• Complete Sequence of a blaOXA-48-Harboring IncL Plasmid from an Enterobacter cloacae Clinical Isolate.

• Manageiro V1, Pinto M2, Caniça M3.
• Genome announcements.Genome Announc.2015 Sep 17;3(5). pii: e01076-15. doi: 10.1128/genomeA.01076-15.
• We report a 63,584-bp conjugative IncL plasmid (pUR17313-1) from an Enterobacter cloacae clinical isolate, containing a blaOXA-48 gene. The plasmid sequence also carried important mobile genetic elements involved in the spread of antibiotic resistance, namely, the Tn1999.2 composite transposon, whic
• PMID 26383652

• Two novel Salmonella genomic island 1 variants in Proteus mirabilis isolates from swine farms in China.

• Lei CW1, Zhang AY1, Liu BH1, Wang HN2, Yang LQ3, Guan ZB1, Xu CW1, Zhang DD1, Yang YQ1.
• Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2015 Jul;59(7):4336-8. doi: 10.1128/AAC.00120-15. Epub 2015 Apr 27.
• Four different Salmonella genomic island 1 (SGI1) variants, including two novel variants, were characterized in one Salmonella enterica serovar Rissen sequence type ST1917 isolate and three Proteus mirabilis isolates from swine farms in China. One novel variant was derived from SGI1-B with the backb
• PMID 25918148

Japanese Journal

• Corrigendum: A novel composite retrotransposon derived from or generated independently of the SVA (SINE/VNTR/Alu) transposon has undergone proliferation ingibbon genomes [Genes Genet. Syst. (2012) 87, p. 181–190]

• Hara Toru,Hirai Yuriko,Baicharoen Sudarath,Hayakawa Takashi,Hirai Hirohisa,Koga Akihiko
• Genes & Genetic Systems 89(3), 149-149, 2014
• This paper was published in error prior to the publication of the gibbon genome sequence assembly and analysis by the Gibbon Genome Analysis Consortium, due to the author's lack of knowledge of the em …
• NAID 130004703734

• Complete sequence of pBFUK1, a carbapenemase-harboring mobilizable plasmid from Bacteroides fragilis, and distribution of pBFUK1-like plasmids among carbapenem-resistant B. fragilis clinical isolates

• GOTO Takatsugu,TANAKA Kaori,TRAN Chau Minh,WATANABE Kunitomo
• Journal of antibiotics 66(4), 239-242, 2013-04-25
• NAID 10031168686

• Tandem repeat sequences evolutionarily related to SVA-type retrotransposons are expanded in the centromere region of the western hoolock gibbon, a small ape

• Hara Toru,Hirai Yuriko,Jahan Israt [他],HIRAI Hirohisa,KOGA Akihiko
• Journal of human genetics 57(12), 760-765, 2012-12-01
• … SVA is a composite retrotransposon thought to have been formed by fusion of three solo elements in the common ancestor of hominoids. …
• NAID 10031145882

Related Links

• Composite transposon - definition from Biology-Online.org

code relate Q2Describe the difference between a simple and composite transposon in bacteria. Which could help bacteria adapt to new environments? Explain how. ... See entire post

• Simple and composite transposon in bacteria?

Describe the difference between a simple and composite transposon in bacteria. Which could help bact... ... The smallest bacterial transposons are called Insertion sequence elements (IS). These transposons are usualy ...

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• adj.

• 複合性の、複合体の、多層の

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complex、complexes、multilayer、multilayered、multislice