competitive muscle relaxant

非脱分極性筋弛緩薬

WordNet

1. make ones way by force; "He muscled his way into the office"
2. animal tissue consisting predominantly of contractile cells (同)muscular_tissue
3. one of the contractile organs of the body (同)musculus
4. authority or power or force (especially when used in a coercive way); "the senators used their muscle to get the party leader to resign"
5. showing a fighting disposition; "highly competitive sales representative"; "militant in fighting for better wages for workers"; "his self-assertive and ubiquitous energy" (同)militant
6. involving competition or competitiveness; "competitive games"; "to improve ones competitive position" (同)competitory
7. subscribing to capitalistic competition (同)free-enterprise, private-enterprise
8. tending to relax or relieve muscular or nervous tension; "a relaxant drug"
9. a drug that relaxes and relieves tension

PrepTutorEJDIC

1. 〈U〉(動物体の組織としての)『筋肉』,筋(きん);〈C〉(体の各部を動かす)筋肉 / 〈U〉力,(特に)筋力,腕力 / 《俗に》(…に)強引に割り込む《+『in on』(『into, through』)+『名』》
2. 競争の,競争による
3. くつろがせる,骨休めになる,気晴らしの
4. 筋肉の,筋力のある / 力ずくの

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English Journal

• Essential oil from Xylopia frutescens Aubl. reduces cytosolic calcium levels on guinea pig ileum: mechanism underlying its spasmolytic potential.

• Souza IL1, Correia AC2, Araujo LC3, Vasconcelos LH4, Silva Mda C5, Costa VC6, Tavares JF7,8, Paredes-Gamero EJ9, Cavalcante Fde A10,11,12, Silva BA13,14.
• BMC complementary and alternative medicine.BMC Complement Altern Med.2015 Sep 16;15:327. doi: 10.1186/s12906-015-0849-3.
• BACKGROUND: Xylopia frutescens Aubl. (embira, semente-de-embira or embira-vermelha), is used in folk medicine as antidiarrheal. The essential oil from its leaves (XF-EO) has been found to cause smooth muscle relaxation. Thus, the aim of this study was to investigate the spasmolytic action by which X
• PMID 26376723

• Relaxant effects of a hydroalcoholic extract of Ruta graveolens on isolated rat tracheal rings.

• Águila L1,2, Ruedlinger J3, Mansilla K4, Ordenes J5, Salvatici R6, de Campos RR7, Romero F8,9.
• Biological research.Biol Res.2015 Jun 5;48:28. doi: 10.1186/s40659-015-0017-8.
• BACKGROUND: Ruta graveolens L. (R. graveolens) is a medicinal plant employed in non-traditional medicines that has various therapeutic properties, including anthelmintic, and vasodilatory actions, among others. We evaluated the trachea-relaxant effects of hydroalcoholic extract of R. graveolens agai
• PMID 26044818

• Antinociceptive, anti-inflammatory and smooth muscle relaxant activities of the pyrrolo[3,4-d]pyridazinone derivatives: Possible mechanisms of action.

• Mogilski S1, Kubacka M2, Redzicka A3, Kazek G2, Dudek M2, Malinka W3, Filipek B2.
• Pharmacology, biochemistry, and behavior.Pharmacol Biochem Behav.2015 Jun;133:99-110. doi: 10.1016/j.pbb.2015.03.019. Epub 2015 Apr 3.
• The aim of this study was to evaluate the analgesic as well as anti-inflammatory activities of the new pyrrolo[3,4-d]pyridazinone derivatives. Moreover, the present study attempted to assess some of the mechanisms involved in the pharmacological activity of these compounds. In the previous studies i
• PMID 25847619

Japanese Journal

• Adrenaline produces the relaxation of guinea-pig airway smooth muscle primarily through the mediation of β_2-adrenoceptors

• TANAKA Yoshio,YAMASHITA Yoko,HORINOUCHI Takahiro,KOIKE Katsuo
• 日本平滑筋学会機関誌 41(3), 153-161, 2005-06
• … The β-adrenoceptor subtype that mediates adrenaline-induced relaxation was pharmacologically identified in smooth muscle cells of the isolated guinea-pig trachea. … The concentration-response curve for adrenaline was shifted rightwards in a competitive fashion by the β_1-/β_2-nonselective antagonists propranolol and bupranolol, with pA_2 values of 8.85 and 8.97, respectively. …
• NAID 110002950127

• MaxiK Channel Mediates β_2-Adrenoceptor-activated Relaxation to Isoprenaline through cAMP-dependent and -independent Mechanisms in Guinea-pig Tracheal Smooth Muscle

• TANAKA Yoshio,YAMASHITA Yoko,YAMAKI Fumiko,HORINOUCHI Takahiro,SHIGENOBU Koki,KOIKE Katsuo
• 日本平滑筋学会機関誌 39(6), 205-219, 2003-12
• … We examined the contribution of large-conductance, Ca^<2+>-sensitive K^+ (MaxiK) channel to β_2-adrenoceptor-activated relaxation to isoprenaline in guinea-pig tracheal smooth muscle focusing on the role for cAMP in the coupling between β_2-adrenoceptor and MaxiK channel. … Isoprenaline-elicited relaxation was confirmed to be mediated through β_2-type of adrenoceptor since the response was antagonized in a competitive fashion by a β_2-selective adrenoceptor antagonist butoxamine with a pA_2 value of 6.56. …
• NAID 110002912881

• Oxybutynin hydrochlorideの摘出平滑筋(回腸,膀胱および尿道)に対する作用

• 会田 陽子,金子 洋子,笠間 俊男
• 日本薬理学雑誌 87(6), 629-639, 1986
• … Effects of oxybutynin hydrochloride on isolated smooth muscle were investigated in preparations of isolated rabbit bladder body, bladder base, collum vesicae and urethra. … Oxybutynin showed a competitive inhibition to contractile response induced by ACh in the ileum and urinary bladder, whose potency was about 1/7 ?? … On the other hand, oxybutynin showed a non-competitive inhibition to contractile response induced by Ba<SUP>2+</SUP>, Ca<SUP>2+</SUP> …
• NAID 130000759693

Related Links

• The “competitive” muscle relaxants - Springer

The mode of action of the “Competitive” or “Blocking” relaxant drugs has been briefly reviewed. The degree of muscular relaxation obtained, the duration of relaxation and the site of relaxation are al

• competitive muscle relaxant - Bing Dictionary

必应词典为您提供competitive muscle relaxant的释义，un. 竞争型肌松药； Web Images Videos Maps News Explore Bing Rewards Sign in competitive muscle relaxant US UK un. 竞争型肌松药 E-C Web Definition un. 1. ... | ...

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★リンクテーブル★

リンク元	「非脱分極性筋弛緩薬」「筋弛緩薬」「競合性筋弛緩薬」
関連記事	「competitive」「muscle relaxant」「muscle」

「非脱分極性筋弛緩薬」

　　[★]

英

nondepolarizing muscle relaxant non-depolarizing muscle relaxant

同

競合的神経筋遮断薬 competitive neuromuscular blocker、競合的筋弛緩薬 competitive muscle relaxant、非脱分極性神経筋遮断薬 non-depolarizing neuromuscular blocker、非脱分極性遮断薬 nondepolarizing blocking drugs、クラーレ様作用薬 curarimimetic、クラーレ様物質

関

脱分極性筋弛緩薬、筋弛緩薬、Train of four monitor、脱分極性遮断薬、神経筋接合部遮断薬

[show details]

非脱分極性遮断薬 : 18 件
非脱分極性筋弛緩薬 : 約 29,600 件
非脱分極性神経筋遮断薬 : 22 件
競合的遮断薬 : 約 48 件
競合的筋弛緩薬 : 約 26 件
競合的神経筋遮断薬 : 16 件

• ニコチン性アセチルコリン受容体にアセチルコリンと競合的に結合することで、アセチルコリンの受容体結合を阻害
• 脱分極させることなく、アセチルコリンと競合してアセチルコリン結合部位への結合を妨げる。

• アトラクリウム

• d-ツボクラリン：ヒスタミン遊離作用を有する。 (=d-tubocurarine(クラーレ))
• パンクロニウム：
• ベクロニウム：
• ロクロニウム：スガマデックスで拮抗される

• 重症筋無力症の場合、(競合してAch受容体を奪うため)少量の非脱分極性筋弛緩薬でも筋弛緩が出現 (SPC.169)

拮抗薬

• 一般的には、コリンエステラーゼ阻害薬であるネオスチグミンやエドロフォニウムを用いる。
• ロクロニウムに対してはスガマデックスを使用することができる。

「筋弛緩薬」

　　[★]

英

muscle relaxant muscle relaxants

同

神経筋接合部遮断薬、骨格筋弛緩薬 skeletal muscle relaxant skeletal muscle relaxants

関

• 競合性筋弛緩薬 competitive muscle relaxant
• 非脱分極性筋弛緩薬 non-depolarizing muscle relaxant
• 脱分極性筋弛緩薬 depolarizing muscle relaxant

筋弛緩のモニタリング(SAN.74-75)

関

四連反応比刺激

• 尺骨神経の走行に沿って2枚の電極を装着して、母指内転筋の収縮を定量化して評価する

「競合性筋弛緩薬」

　　[★]

英

competitive muscle relaxant

関

非脱分極性筋弛緩薬

「competitive」

　　[★]

• 競合的な、競合性の、競合する、競争の

関

compete、competition、competitively、competitiveness、contest、rival

　 　 　 　

「muscle relaxant」

　　[★]

• 筋弛緩薬、筋弛緩剤

関

skeletal muscle relaxant

「muscle」

　　[★]

• n.

• 筋肉