collagen type IV

IV型コラーゲン

関

collagen IV、type IV collagen

WordNet

1. write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
2. a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
3. (biology) the taxonomic group whose characteristics are used to define the next higher taxon
4. a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
5. all of the tokens of the same symbol; "the word `element contains five different types of character"
6. printed characters; "small type is hard to read"
7. identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
8. a paste-up made by sticking together pieces of paper or photographs to form an artistic image; "he used his computer to make a collage of pictures superimposed on a map" (同)montage
9. any collection of diverse things; "a collage of memories"
10. the 9th letter of the Roman alphabet (同)i
11. a fibrous scleroprotein in bone and cartilage and tendon and other connective tissue; yields gelatin on boiling
12. writing done with a typewriter (同)typewriting

PrepTutorEJDIC

1. 〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
2. コラージュ / 〈C〉画面に絵具以外のいろいろな素材を貼り付けて耕成した絵 / 〈U〉1の絵画技法
3. 『私は』私が
4. iodineの化学記号

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/11/29 00:51:38」(JST)

wiki en

[Wiki en表示]

Type-IV collagen is a type of collagen found primarily in the basal lamina. The type IV collagen C4 domain at the C-terminus is not removed in post-translational processing, and the fibers link head-to-head, rather than in parallel. Also, type-IV lacks the regular glycine in every third residue necessary for the tight, collagen helix. This makes the overall arrangement more sloppy with kinks. These two features cause the collagen to form in a sheet, the form of the basal lamina

There are six human genes associated with it:

• COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6

Clinical significance

The alpha 3 protein constituent of type-IV collagen is thought to be the antigen implicated in Goodpasture's syndrome, wherein the immune system attacks the basement membranes of the glomeruli and the alveoli.

Mutations to the genes coding for type-IV collagen lead to Alport syndrome.

References

External links

• Collagen+type+IV at the US National Library of Medicine Medical Subject Headings (MeSH)

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 遺伝性腎炎（アルポート症候群）の遺伝学、病因、および病理 genetics pathogenesis and pathology of hereditary nephritis alport syndrome
• 2. 遺伝性腎炎（アルポート症候群）の臨床症状、診断および治療 clinical manifestations diagnosis and treatment of hereditary nephritis alport syndrome
• 3. 菲薄基底膜腎症（良性家族性血尿） thin basement membrane nephropathy benign familial hematuria
• 4. 肝線維症の非侵襲的評価：血清学的検査および画像診断 noninvasive assessment of hepatic fibrosis overview of serologic and radiographic tests
• 5. 抗GBM抗体（グッドパスチャー）病の病因および診断 pathogenesis and diagnosis of anti gbm antibody goodpastures disease

English Journal

• Biophysical characteristics of cells cultured on cholesteryl ester liquid crystals.

• Soon CF, Omar WI, Berends RF, Nayan N, Basri H, Tee KS, Youseffi M, Blagden N, Denyer MC.SourceBiosensor and Bioengineering Laboratory, MiNT-SRC Research Center, Universiti Tun Hussein Onn Malaysia, 86400 Parit Raja, Batu Pahat, Johor, Malaysia; School of Medical Sciences, University of Bradford, Bradford BD7 1DP, United Kingdom. Electronic address: fionasoon@gmail.com.
• Micron (Oxford, England : 1993).Micron.2014 Jan;56:73-9. doi: 10.1016/j.micron.2013.10.011. Epub 2013 Oct 24.
• This study aimed at examining the biophysical characteristics of human derived keratinocytes (HaCaT) cultured on cholesteryl ester liquid crystals (CELC). CELC was previously shown to improve sensitivity in sensing cell contractions. Characteristics of the cell integrin expressions and presence of e
• PMID 24231674

• Matrix metalloproteinase-2 deletions protect against hemorrhagic transformation after 1h of cerebral ischemia and 23h of reperfusion.

• Lu A, Suofu Y, Guan F, Broderick JP, Wagner KR, Clark JF.SourceDepartment of Neurology, University of Cincinnati, Cincinnati, OH 45267-0532, USA. Electronic address: lua@ucmail.uc.edu.
• Neuroscience.Neuroscience.2013 Dec 3;253:361-7. doi: 10.1016/j.neuroscience.2013.08.068. Epub 2013 Sep 12.
• Although elevated matrix metalloproteinase (MMP)-2 levels were highly related to the degradation of tight junction (TJ) proteins and basal lamina and neuronal injury after ischemia, until very recently, little experimental evidence was available to test the role of the MMP-2 knockout (KO) in blood-b
• PMID 24035828

• p38 mitogen-activated protein kinase interacts with vinculin at focal adhesions during fatty acid-stimulated cell adhesion.

• George MD, Wine RN, Lackford B, Kissling GE, Akiyama SK, Olden K, Roberts JD.SourceNational Institute of Environmental Health Sciences, 111 T.W. Alexander Drive, Research Triangle Park, NC 27709, USA.
• Biochemistry and cell biology = Biochimie et biologie cellulaire.Biochem Cell Biol.2013 Dec;91(6):404-18. doi: 10.1139/bcb-2013-0013. Epub 2013 Jun 24.
• Arachidonic acid stimulates cell adhesion by activating α2β1 integrins in a process that depends on protein kinases, including p38 mitogen activated protein kinase. Here, we describe the interaction of cytoskeletal components with key signaling molecules that contribute to the spreading of, and mo
• PMID 24219282

Japanese Journal

• 細胞を用いた水晶体再生の基礎検討 ─不死化水晶体上皮細胞による三次元水晶体再構築モデル作製の試み─

• 日本白内障学会誌 28(1), 106-110, 2016
• NAID 130005162901

• Histological and immunohistochemical evaluation of stroma variations and their correlation with the Ki-67 index and expressions of glucose transporter 1 and monocarboxylate transporter 1 in canine thyroid C-cell carcinomas

• Journal of Veterinary Medical Science advpub(0), 607-612, 2016
• NAID 130005115352

• Preparation of inactivated human skin using high hydrostatic pressurization for full-thickness skin reconstruction

• PLOS ONE 10(7), 2015-07-30
• NAID 120005763411

Related Links

• コラーゲンⅠ／Ⅲ／Ⅳ | 細胞外マトリックス | フナコシ

Collagen Type IV, Bovine Lens, Acid Soluble (0.5mg/ml) 1ml \36,000 無 (未発注) 追加 [在庫 ： 2015年11月07日 09時44分 現在] メーカー 商品コード 商品名 包装 価格 在庫 リスト NIP ニッピ （株）ニッピ ASC-1-100-20 Collagen Type ...

• Ⅳ型コラーゲン, type IV collagen - 国立大学法人 岡山大学

Ⅳ型コラーゲン, type IV collagen 測定法： ラテックス凝集法 EIA法(平成16年3月31日まで） 外注会社：BML 臨床的意義 IV型コラーゲンは基底膜緻密層の主要構成成分であり、線維束を形成するコラーゲンと異なり、シートを ...

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★リンクテーブル★

リンク元	「type IV collagen」
関連記事	「type」「I」「IV」「typed」「typing」

「type IV collagen」

　　[★]

IV型コラーゲン

関

collagen IV、collagen type IV

「type」

　　[★]

• n.

• 型、タイプ、(生物)タイプ標本

(windows)ファイル内容表示(linux -> cat])

ex. type report_20111118.jp.htm | php a.php > report_20111118.jp.jp.jp.html

関

form、mode、pattern、type specimen、typed

　 　 　 　 　 　 　 　

「I」

　　[★]

• イソロイシン isoleucine
• イノシン inosine
• 阻害剤 inhibitor
• iodine
• ヨード iodide
• I因子 factor I

　 　 　

「IV」

　　[★]

• adj.

• 静脈内の

関

i.v.、intravascular、intravenous、intravenously

「typed」

　　[★]

• adj.

• 型の

関

form、mode、pattern、type

「typing」

　　[★]

• n.

• タイプで打つこと、タイピング。分類