関: COP

WordNet

any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"

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蛋白(たんばく)質

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/12/10 01:27:56」(JST)

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Archain is a protein located on chromosome 11. Also known as ARCH1, it plays a role in eukaryotic cell biology.

It is part of the COPI coatomer complex.^[1]

References[edit]

^ Xu X, Kedlaya R, Higuchi H, et al. (2010). "Mutation in archain 1, a subunit of COPI coatomer complex, causes diluted coat color and Purkinje cell degeneration". PLoS Genet. 6 (5): e1000956. doi:10.1371/journal.pgen.1000956. PMC 2873907. PMID 20502676.

External links[edit]

Archain at the US National Library of Medicine Medical Subject Headings (MeSH)

This article on a gene on chromosome 11 is a stub. You can help Wikipedia by expanding it.

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1. 幼児の食物蛋白誘発性直腸炎/大腸炎および腸疾患 food protein induced proctitis colitis and enteropathy of infancy
2. 活性化プロテインＣ抵抗性および第V因子ライデン activated protein c resistance and factor v leiden
3. 肥大型心筋症の遺伝学 genetics of hypertrophic cardiomyopathy
4. 食物蛋白誘発胃腸炎（新生児-乳児消化管アレルギー）（FPIES） food protein induced enterocolitis syndrome fpies
5. プロテインＳ欠乏症 protein s deficiency

English Journal

Exosome Proteome of U-87MG Glioblastoma Cells.

Chun S1, Ahn S2,3, Yeom CH4, Park S5.
Biology.Biology (Basel).2016 Dec 6;5(4). pii: E50.
Exosomes are small membrane vesicles between 30 and 100 nm in diameter secreted by many cell types, and are associated with a wide range of physiological and/or pathological processes. Exosomes containing proteins, lipids, mRNA, and microRNA contribute to cell-to-cell communication and cell-to-envir
PMID 27929413

Circulating Anti-Coatomer Protein Complex Subunit Epsilon (COPE) Autoantibodies as a Potential Biomarker for Cardiovascular and Cerebrovascular Events in Patients with Obstructive Sleep Apnea.

Matsumura T, Terada J, Kinoshita T, Sakurai Y, Yahaba M, Ema R, Amata A, Sakao S, Nagashima K, Tatsumi K, Hiwasa T.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.J Clin Sleep Med.2016 Nov 28. pii: jc-00251-16. [Epub ahead of print]
STUDY OBJECTIVES: Although moderate to severe obstructive sleep apnea (OSA) is an independent risk factor for severe arteriosclerotic diseases such as cardiovascular disease (CVD) and stroke, the development of atherosclerosis-related diseases cannot yet be predicted in OSA patients. In a pilot stud
PMID 27923433

Discovery Proteomics Identifies a Molecular Link between the Coatomer Protein Complex I and Androgen Receptor-dependent Transcription.

Hsiao JJ1, Smits MM1, Ng BH1, Lee J1, Wright ME2.
The Journal of biological chemistry.J Biol Chem.2016 Sep 2;291(36):18818-42. doi: 10.1074/jbc.M116.732313. Epub 2016 Jun 30.
Aberrant androgen receptor (AR)-dependent transcription is a hallmark of human prostate cancers. At the molecular level, ligand-mediated AR activation is coordinated through spatial and temporal protein-protein interactions involving AR-interacting proteins, which we designate the "AR-interactome."
PMID 27365400

Japanese Journal

Cloning and tissue-specific expression of a δ-COP homologue in a freshwater and a brackish water-adapted strain of rainbow trout : Oncorhynchus mykiss

Genes & genetic systems 84(3), 239-243, 2009-06-25
NAID 10026091109

Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the β-subunit of coatomer complex, β-COP

Journal of biological chemistry 281(16), 11214-11224, 2006-04-21
NAID 80019185214

Phylogenetic analysis of components of the eukaryotic vesicle transport system reveals a common origin of adaptor protein complexes 1, 2, and 3 and the F subcomplex of the coatomer COPI

J Mol Evol 48, 770-778, 1999
NAID 80011188994

「コートマータンパク質」

archain 1
Identifiers
Symbol	ARCN1
Alt. symbols	COPD
Entrez	372
HUGO	649
OMIM	600820
RefSeq	NM_001655
UniProt	P48444
Other data
Locus	Chr. 11 q23.3

　　[★]

英: coatomer protein、COP
関: コートタンパク質

[pmid20502676-1] Xu X, Kedlaya R, Higuchi H, et al. (2010). "Mutation in archain 1, a subunit of COPI coatomer complex, causes diluted coat color and Purkinje cell degeneration". PLoS Genet. 6 (5): e1000956. doi:10.1371/journal.pgen.1000956. PMC 2873907. PMID 20502676.

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案内

coatomer protein