ciclopirox olamine

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/07/12 20:31:25」(JST)

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  • In vitro permeation and penetration of ciclopirox olamine from poloxamer 407-based formulations - comparison of isolated human stratum corneum, bovine hoof plates and keratin films.
  • Täuber A1, Müller-Goymann CC2.
  • International journal of pharmaceutics.Int J Pharm.2015 Jul 15;489(1-2):73-82. doi: 10.1016/j.ijpharm.2015.04.043. Epub 2015 Apr 17.
  • Fungal infections of skin and/or nails are common diseases resulting in major challenges in topical treatment. Therefore, the objective of the present study was to develop a dermal formulation targeting both tinea pedis and onychomycosis. The antifungal agent ciclopirox olamine (CPX) was incorporate
  • PMID 25895717
  • In Vitro Antifungal Activity of ME1111, a New Topical Agent for Onychomycosis, against Clinical Isolates of Dermatophytes.
  • Ghannoum M1, Isham N2, Long L2.
  • Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2015 Jun 8. pii: AAC.00992-15. [Epub ahead of print]
  • BACKGROUND: The treatment of onychomycosis has improved considerably over the past several decades following the introduction of the oral antifungals terbinafine and itraconazole. However, these oral agents suffer from certain disadvantages, including drug interactions and potential liver toxicity.
  • PMID 26055386
  • [Cutaneous Malassezia infections and Malassezia associated dermatoses : An update].
  • Nenoff P1, Krüger C, Mayser P.
  • Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete.Hautarzt.2015 Jun;66(6):465-86. doi: 10.1007/s00105-015-3631-z.
  • The lipophilic yeast fungus Malassezia (M.) spp. is the only fungal genus or species which is part of the physiological human microbiome. Today, at least 14 different Malassezia species are known; most of them can only be identified using molecular biological techniques. As a facultative pathogenic
  • PMID 25968082


  • Effects of Antifungal Drugs on Proliferation Signals in Candida albicans(Microbiology)
  • , , [他], , ,
  • Biological & pharmaceutical bulletin 29(5), 919-922, 2006-05-01
  • Ciclopirox olamine and siccanin were more effective under aerobic than under anaerobic conditions. …
  • NAID 110005602214
  • Crystal Structure of Ciclopirox Olamine
  • ,
  • Analytical Sciences: X-ray Structure Analysis Online 19, X21-X22, 2003
  • … The crystal structure of ciclopirox was determined. … There are two ciclopirox molecules, of which one is neutral and the other is negatively charged, and one positively charged 2-amino ethanol molecule in an asymmetric unit. …
  • NAID 130004442506
  • A randomised, single-blind, single-centre clinical trial to evaluate comparative clinical efficacy of shampoos containing ciclopirox olamine (1.5%) and salicylic acid (3%), or ketoconazole (2%, Nizoral) for the treatment of dandruff/seorrhoeic dermatitis


ci·clo·pir·ox ol·a·mine (sī′klō-pîr′ŏks′ ô′lə-mēn′, sĭk′lō-) n. A broad-spectrum antifungal agent used in the treatment of a variety of fungal and yeast infections of the skin. ciclopirox olamine (sik´lōpē´roks) (topical), n brand name: Loprox; ...
Ciclopirox Olamine reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI). ... Cautions for Ciclopirox Olamine Contraindications Known hypersensitivity to ciclopirox, ciclopirox ...


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