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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2018/05/01 02:38:50」(JST)
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"Chronotherapy" redirects here. For other uses, see Chronotherapy (sleep phase).
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| Chronotherapy (treatment scheduling) |
| MeSH |
D019454 |
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[edit on Wikidata]
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Chronotherapy, also called chronotherapeutics[1] or chronotherapeutic drug delivery,[2] refers to the use of circadian or other rhythmic cycles of a condition's symptoms and/or of the individual being treated in the application of therapy.[2] Examples of this are treatments of psychiatric and somatic diseases that are administered according to a schedule that corresponds to these rhythms in order to maximize effectiveness and minimize side effects of the therapy.[3]
Chronotherapy is used in various clinical fields such as the treatments of asthma,[4][5] cancer, hypertension,[6] and multiple types of depression, among others seasonal affective disorder and bipolar disorder.
Chronotherapy is also becoming increasingly popular in non-clinical settings, for example on the work floor, where it is used to increase productivity and performance.[citation needed]
Contents
- 1 Methods of chronotherapy
- 1.1 Methods of pharmaceutical chronotherapy
- 2 See also
- 3 References
Methods of chronotherapy
Methods of pharmaceutical chronotherapy
- Imitative/Mimetic: Imitating the natural changes in a certain substance in the body.
- Preventive/Precautionary: Taking medicines at the moment that they are most necessary, for example taking hypertension medicine at the time of day that the blood pressure is rising.
- Wake therapy
See also
References
- ^ "Medical dictionary". Merriam-Webster. Retrieved 6 January 2017.
- ^ a b Sajan, J (October 2009). "Chronotherapeutics and Chronotherapeutic Drug Delivery Systems". Tropical Journal of Pharmaceutical Research. 8 (5): 467–475. doi:10.4314/tjpr.v8i5.48091. ISSN 1596-5996. Retrieved 6 January 2017.
...drug availability is timed to match rhythms of disease in order to optimize therapeutic outcomes and minimize side effects.
- ^ "Dictionary Definition".
- ^ "Chronotherapy of asthma with inhaled steroids: The effect of dosage timing on drug efficacy". Journal of Allergy and Clinical Immunology. 95: 1172–1178. doi:10.1016/S0091-6749(95)70073-0.
- ^ "Further studies on the chronotherapy of asthma with inhaled steroids: The effect of dosage timing on drug efficacy". Journal of Allergy and Clinical Immunology. 100: 771–774. doi:10.1016/S0091-6749(97)70272-0.
- ^ "Circadian variation of blood pressure: The basis for the chronotherapy of sleeping disorders, hypertension". Advanced Drug Delivery Reviews. 59 (9–10): 904–922. doi:10.1016/j.addr.2006.08.003.
English Journal
- The effect of white light on normal and malignant murine melanocytes: A link between opsins, clock genes, and melanogenesis.
- de Assis LV1, Moraes MN1, da Silveira Cruz-Machado S2, Castrucci AM3.
- Biochimica et biophysica acta.Biochim Biophys Acta.2016 Jun;1863(6 Pt A):1119-33. doi: 10.1016/j.bbamcr.2016.03.001. Epub 2016 Mar 3.
- The skin possesses a photosensitive system comprised of opsins whose function is not fully understood, and clock genes which exert an important regulatory role in skin biology. Here, we evaluated the presence of opsins in normal (Melan-a cells) and malignant (B16-F10 cells) murine melanocytes. Both
- PMID 26947915
- Dosing-Time Makes the Poison: Circadian Regulation and Pharmacotherapy.
- Dallmann R1, Okyar A2, Lévi F3.
- Trends in molecular medicine.Trends Mol Med.2016 May;22(5):430-45. doi: 10.1016/j.molmed.2016.03.004. Epub 2016 Apr 5.
- Daily rhythms in physiology significantly modulate drug pharmacokinetics and pharmacodynamics according to the time-of-day, a finding that has led to the concept of chronopharmacology. The importance of biological clocks for xenobiotic metabolism has gained increased attention with the discovery of
- PMID 27066876
- Circadian Metabolism: From Mechanisms to Metabolomics and Medicine.
- Brown SA1.
- Trends in endocrinology and metabolism: TEM.Trends Endocrinol Metab.2016 Apr 21. pii: S1043-2760(16)30001-7. doi: 10.1016/j.tem.2016.03.015. [Epub ahead of print]
- The circadian clock directs nearly all aspects of diurnal physiology, including metabolism. Current research identifies several major axes by which it exerts these effects, including systemic signals as well as direct control of cellular processes by local clocks. This redundant network can transmit
- PMID 27113082
Japanese Journal
- 医薬品医療機器レギュラトリーサイエンス = Pharmaceutical and medical device regulatory science 46(12), 837-845, 2015
- NAID 40020678999
- くすりと糖尿病 : Japanese journal of pharmaceutical and diabetes 4(1), 62-68, 2015
- NAID 40020659055
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