WordNet

being long-lasting and recurrent or characterized by long suffering; "chronic indigestion"; "a chronic shortage of funds"; "a chronic invalid"
of long duration; "chronic money problems" (同)continuing
habitual; "a chronic smoker" (同)inveterate

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The new era for the treatment of psoriasis and psoriatic arthritis: Perspectives and validated strategies.

Novelli L, Chimenti MS, Chiricozzi A, Perricone R.SourceRheumatology, Allergology and Clinical Immunology, Department of Internal Medicine, University of Tor Vergata, Rome, Italy.
Autoimmunity reviews.Autoimmun Rev.2014 Jan;13(1):64-9. doi: 10.1016/j.autrev.2013.08.006. Epub 2013 Sep 8.
Psoriatic Arthritis (PsA) is a chronic inflammatory arthropathy associated with psoriasis. Psoriasis (PsO) is a chronic, inflammatory skin disease, characterized by hyperproliferation and aberrant differentiation of keratinocytes. PsA and PsO can be considered as a unique disease and are immune-medi
PMID 24021172

Modulating the co-stimulatory signal for T cell activation in rheumatoid arthritis: Could it be the first step of the treatment?

Caporali R, Bugatti S, Cavagna L, Antivalle M, Sarzi-Puttini P.SourceDivision of Rheumatology, University of Pavia, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy. Electronic address: caporali@smatteo.pv.it.
Autoimmunity reviews.Autoimmun Rev.2014 Jan;13(1):49-53. doi: 10.1016/j.autrev.2013.06.008. Epub 2013 Jun 15.
Advances in our understanding of the key mediators of chronic inflammation and tissue damage in rheumatoid arthritis (RA) have fostered the development of targeted therapies and greatly expanded the available treatment options. Abatacept, a soluble human fusion protein that selectively modulates the
PMID 23777823

守川耕平,久保幸也,信川真智子,信川真貴子,信川京子,岡野哲郎
日本補完代替医療学会誌 8(1), 17-23, 2011
はじめに：現在動物における適当な ADL 評価法はない．そこで，リウマチの動物モデル，II 型コラーゲン誘発関節炎ラットを用いリウマチ発症に伴う疼痛の緩和効果を疼痛に効果があると言われている紅豆杉を用いて検討し，新たな行動回復評価法開発とそれに伴う紅豆杉の補完医学素材について検討した．方法：ラット回避行動の習性を利用し行動の変化を 10 段階でスコア化した．リウマチ重症ラットを用い，水摂取群をコ …
NAID 130000654938

OOHASHI Eiji,YAMADA Kazutaka,OOHASHI Mirai,UEDA Junji
日本獣醫學会会誌 72(4), 511-514, 2010
… Feline chronic progressive polyarthritis is a rare immune-mediated disease that has only previously been reported in male cats. … The cat was clinically diagnosed with chronic progressive polyarthritis based on the fever, swelling of joints, imaging of erosive proliferative periosteal polyarthritis, positivity for antinuclear antibody, synovial fluid analyses and urinalyses. …
NAID 130000149950