WordNet

being long-lasting and recurrent or characterized by long suffering; "chronic indigestion"; "a chronic shortage of funds"; "a chronic invalid"
of long duration; "chronic money problems" (同)continuing
habitual; "a chronic smoker" (同)inveterate

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1. 慢性化膿性中耳炎（CSOM）：病因、臨床症状、および診断 chronic suppurative otitis media csom pathogenesis clinical manifestations and diagnosis
2. 女性における慢性骨盤痛の原因 causes of chronic pelvic pain in women
3. 慢性蕁麻疹：難治性症状の治療 chronic urticaria treatment of refractory symptoms
4. 慢性蕁麻疹：標準的なマネージメントおよび患者教育 chronic urticaria standard management and patient education
5. 慢性期の慢性骨髄性白血病の初期治療 initial treatment of chronic myeloid leukemia in chronic phase

Expression and clinical significance of LRRC4 in benign and malignant nasopharyngeal diseases.

Zhou XJ1, Wang Y2, Zhang LJ1, Chen JH3.
Genetics and molecular research : GMR.Genet Mol Res.2015 Dec 9;14(4):16403-16409.
The aim of this study was to investigate the expression of LRRC4 in nasopharyngeal carcinomas, nasopharyngeal precancerous lesions, and nasopharyngitis as well as the clinical significance of LRRC4. Fifty patients with nasopharyngeal carcinoma were selected as study subjects; 28 patients with chroni
PMID 26662436

Safety and tolerability of ibrutinib monotherapy in Japanese patients with relapsed/refractory B cell malignancies.

Tobinai K1, Ogura M2, Ishizawa K3, Suzuki T4,2, Munakata W4, Uchida T2, Aoki T2, Morishita T2, Ushijima Y2, Takahara S5.
International journal of hematology.Int J Hematol.2015 Nov 20. [Epub ahead of print]
In this phase I dose-escalation study we evaluated the safety, tolerability, pharmacokinetics, and antitumor activity of ibrutinib, an oral covalent inhibitor of Bruton's tyrosine kinase (BTK, in Japanese patients with relapsed/refractory B cell malignancies (RRBCM). Fifteen patients aged 42-78 yea
PMID 26588924

López-Ferrer A1, Vilarrasa E1, Puig L.
Expert review of clinical immunology.Expert Rev Clin Immunol.2015 Nov;11(11):1177-88. doi: 10.1586/1744666X.2015.1095092. Epub 2015 Oct 1.
Psoriasis is a chronic inflammatory disease with a multifactorial origin that appears in patients with genetic predisposition and is induced by environmental factors, and characterized by alterations in the innate and adaptive immunity. IL-17A is one of the specific cytokines involved in the pathoge
PMID 26428036