chronic drug-induced tubulointerstitial nephritis

慢性薬剤性尿細管間質性腎炎

WordNet

1. reason or establish by induction
2. cause to arise; "induce a crisis" (同)bring_on
3. produce electric current by electrostatic or magnetic processes (同)induct
4. cause to do; cause to act in a specified manner; "The ads induced me to buy a VCR"; "My children finally got me to buy a computer"; "My wife made me buy a new sofa" (同)stimulate, cause, have, get, make
5. cause to occur rapidly; "the infection precipitated a high fever and allergic reactions" (同)stimulate, rush, hasten
6. being long-lasting and recurrent or characterized by long suffering; "chronic indigestion"; "a chronic shortage of funds"; "a chronic invalid"
7. of long duration; "chronic money problems" (同)continuing
8. habitual; "a chronic smoker" (同)inveterate
9. use recreational drugs (同)do drugs
10. administer a drug to; "They drugged the kidnapped tourist" (同)dose
11. a substance that is used as a medicine or narcotic
12. brought about or caused; not spontaneous; "a case of steroid-induced weakness"
13. an inflammation of the kidney (同)Bright''s disease

PrepTutorEJDIC

1. 〈人〉‘に'『勧めて』(…)『させる』 / …‘を'『引き起こす』,もたらす(cause) / 〈電気〉‘を'誘導する / …‘を'帰納する
2. (病気が)長期にわたる,慢性の / 《名詞の前にのみ用いて》常習の,癖になった
3. 『薬』,薬品,薬剤 / 『麻薬』,麻酔剤 / 〈人〉‘に'薬(特に麻酔剤)を与える / 〈飲食物〉‘に'(麻酔薬・毒薬などの)薬を混ぜる
4. 腎炎(じんえん)

UpToDate Contents

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• 1. リチウムの腎毒性renal toxicity of lithium [show details]
  … development of interstitial nephritis and renal fibrosis. With chronic use in humans, nephrogenic diabetes insipidus (NDI) often becomes irreversible. In one study, patients who had been on the drug for more… the lithium-induced concentrating defect may be permanent after prolonged therapy . When lithium-induced NDI is diagnosed, discontinuation of the drug may be appropriate.…
• 2. 急性間質性腎炎の治療treatment of acute interstitial nephritis [show details]
  … AIN due to drugs will be reviewed here The manifestations and diagnosis of AIN and the approach to the management of patients diagnosed with infection-induced AIN, tubulointerstitial nephritis and uveitis …
• 3. シェーグレン症候群における腎疾患kidney disease in sjogrens syndrome [show details]
  … causes of this disorder: chronic lithium ingestion or hypercalcemia. The tubular injury induced by the interstitial nephritis indirectly leads to potassium… can be induced by a variety of drugs. In addition, patients with immunoglobulin G4 (IgG4)-related disease may have salivary and lacrimal gland involvement, as well as interstitial nephritis.…
• 4. 尿路性器結核urogenital tuberculosis [show details]
  … favor formation of medullary granulomas or chronic tubulointerstitial nephritis.… Acute allergic interstitial nephritis may also occur as a result of drugs used to treat TB,… bloodstream through the thoracic duct and silently disseminate to the kidneys. The inflammatory response induces formation of a cortical granuloma, which may heal and form a microscopic scar. Organisms may remain …
• 5. 鎮痛薬に起因する慢性腎臓病（鎮痛薬腎症）の疫学と発症機序epidemiology and pathogenesis of analgesic related chronic kidney disease [show details]
  …NSAIDs are common causes of drug-induced acute interstitial nephritis (AIN). Patients who develop NSAID-induced AIN are at risk for CKD from chronic interstitial nephritis. This was suggested by review …

English Journal

• PMID 34187299
• PMID 34461843
• PMID 34167986

Japanese Journal

• Infliximab-Induced Tubulointerstitial Nephritis with Image Findings of Striated Nephrogram in Crohn's Disease

• Sato Tomonori,Arai Yoichi,Kawasaki Yoshihide,Ito Akihiro,Izumi Hideaki,Kawamorita Naoki,Yamashita Shinichi,Mitsuzuka Koji,Matsuura Tomonori,Watanabe Mika
• The Tohoku Journal of Experimental Medicine 245(3), 149-152, 2018
• … <p>Tubulointerstitial nephritis is primary injury to renal tubules and interstititum which could be resulting in decreased renal function. … The acute and chronic forms are most often due to allergic drug reactions or to infections. … Tubulointerstitial nephritis in Crohn's disease has rarely been reported. …
• NAID 130007394078

• Drug-induced kidney disease: a study of the Japan Renal Biopsy Registry from 2007 to 2015

• Yokoyama Hitoshi,Narita Ichie,Sugiyama Hitoshi,Nagata Michio,Sato Hiroshi,Ueda Yoshihiko,Matsuo Seiichi,長田 道夫
• Clinical and experimental nephrology 20(5), 720-730, 2016-10
• … The number of cases peaked in the 6th–8th decade in all pathological categories, except for the number of chronic tubulointerstitial lesions (CTIL), which peaked in the 4th–5th decade. … The main clinical diagnoses were DIKD in 150 cases (45.7 %), nephrotic syndrome in 66 cases (20.1 %), chronic nephritic syndrome in 55 cases (16.8 %), and rapidly progressive glomerulonephritis in 30 cases (9.1 %). …
• NAID 120005867133

Related Links

• Drug-induced tubulointerstitial nephritis: hypersensitivity and ...

Other drugs, classified as potential nephrotoxins, may induce dose-dependent acute tubular necrosis. Studies over the past decade have identified a unique form of tubular cell death called "necroptosis" that is accompanied by a specific and significant interstitial inflammatory response to certain insults, including some nephrotoxins.

• Drug-induced chronic tubulointerstitial nephritis - Oxford Medicine

The chronic form of drug-induced tubulointerstitial nephritis (CTIN) is an insidious disease and most probably represents the common final response pattern of the kidney to a variety of agents (including analgesics, lithium, antineoplastic chemotherapeutic agents, like cisplatin and nitrosoureas, and immunosuppressive drugs, such as ciclosporin and tacrolimus).

• Drug-induced tubulointerstitial nephritis: hypersensitivity and ...

More than 250 drugs carry a small but important dose-independent risk of initiating a delayed-type hypersensitivity reaction that leads to acute tubulointerstitial nephritis (TIN). Clinical manifestations are often non-specific, making epidemiological studies challenging. In severe cases, if cessation of the offending drug is not followed by a prompt improvement in renal function ...

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★リンクテーブル★

リンク元	「慢性薬剤性尿細管間質性腎炎」
関連記事	「induce」「induced」「chronic」「nephritis」「drug」

「慢性薬剤性尿細管間質性腎炎」

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英

chronic drug-induced tubulointerstitial nephritis

[show details]

ja

chronic drug-induced interstitial nephritis : nothing
chronic drug-induced tubulointerstitial nephritis : 7 件
drug-induced chronic interstitial nephritis : nothing
drug-induced chronic tubulointerstitial nephritis : 4 件

en

chronic drug-induced interstitial nephritis : 23 件
chronic drug-induced tubulointerstitial nephritis : 約 37 件
drug-induced chronic interstitial nephritis : 約 17 件
drug-induced chronic tubulointerstitial nephritis : 約 19 件

「induce」

　　[★]

• v.

• 誘発する、誘導する、誘起する、導入する、引き起こす

関

cause、challenge、derivation、elicit、elicitation、evocation、evoke、guidance、induction、inductive、introduce、introduction、precipitate、provocation、provoke、spark

　 　 　 　 　 　

「induced」

　　[★]

• v.

• (induceの過去分詞)誘導される、引き起こされる

hypercalcaemia induced pancreatitis 高カルシウム血症による膵炎

　

「chronic」

　　[★]

• adj.

• 慢性の、慢性的な、慢性型の

関

chronically、chronicity

　 　 　 　

「nephritis」

　　[★]

関

specific types

関

specific types

関

specific types

　 　

「drug」

　　[★]

同

drugs