chromosomal aberration

出典: meddic

abnormal karyotypechromosomal abnormalitychromosomal anomalychromosomal disorderchromosome aberrationchromosome abnormalitycytogenetic aberrationcytogenetic abnormality

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/01/24 18:35:52」(JST)

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英文文献

  • Evaluation of the toxic effects of four anti-cancer drugs in plant bioassays and its potency for screening in the context of waste water reuse for irrigation.
  • Lutterbeck CA1, Kern DI2, Machado ÊL3, Kümmerer K4.
  • Chemosphere.Chemosphere.2015 Sep;135:403-10. doi: 10.1016/j.chemosphere.2015.05.019. Epub 2015 May 22.
  • Anti-cancer drugs are compounds that are of high environmental relevance because of their lack of specific mode of action. They can be extremely harmful to living organisms even at low concentrations. The present study evaluated the toxic effects of four frequently used anti-cancer drugs against pla
  • PMID 26002047
  • Alu-mediated diverse and complex pathogenic copy-number variants within human chromosome 17 at p13.3.
  • Gu S1, Yuan B1, Campbell IM1, Beck CR1, Carvalho CM1, Nagamani SC2, Erez A3, Patel A1, Bacino CA2, Shaw CA1, Stankiewicz P1, Cheung SW1, Bi W1, Lupski JR4.
  • Human molecular genetics.Hum Mol Genet.2015 Jul 15;24(14):4061-77. doi: 10.1093/hmg/ddv146. Epub 2015 Apr 23.
  • Alu repetitive elements are known to be major contributors to genome instability by generating Alu-mediated copy-number variants (CNVs). Most of the reported Alu-mediated CNVs are simple deletions and duplications, and the mechanism underlying Alu-Alu-mediated rearrangement has been attributed to no
  • PMID 25908615
  • The human papillomavirus18 E7 protein inhibits CENP-C binding to α-satellite DNA.
  • Yaginuma Y1, Yoshimoto M2, Eguchi A2, Tokuda A3, Takahashi S3.
  • Virus research.Virus Res.2015 Jul 2;205:27-32. doi: 10.1016/j.virusres.2015.04.019. Epub 2015 May 18.
  • Human papillomavirus (HPV) infection leads to aneuploidy, a numerical chromosomal aberration that is caused by dysregulation of chromosomal segregation. We previously found that the E7 proteins of high-risk HPVs, but not of low-risk HPVs, could bind to centromere protein-C (CENP-C). In this study, w
  • PMID 25997930

和文文献

  • Triploid human embryonic stem cells derived from tripronuclear zygotes displayed pluripotency and trophoblast differentiation ability similar to the diploid human embryonic stem cells
  • 多発性骨髄腫の治療方針に必要な染色体・遺伝子検査 (特集 血液疾患の治療前必須検査とその解釈)
  • 希少糖含有シロップの安全性評価:ラットにおける単回投与毒性試験,変異原性試験,染色体異常試験およびヒトにおける一過性下痢に対する単回摂取時における最大無作用量

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★リンクテーブル★
リンク元染色体異常」「chromosomal abnormality」「chromosome aberration」「chromosome abnormality」「cytogenetic abnormality
関連記事aberration」「chromosomal

染色体異常」

  [★]

aberration
chromosome aberration, chromosomal aberration, chromosome abnormality, chromosome anomaly
白血病染色体検査


概念

  • 染色体の数および構造の変化

種類

  • 数的異常
  • 倍数性異常
  • 異数性異常
  • 45,XO:Turner症候群 (45X/46XX (モザイク)、46XXq、46XXpもありうる)
  • 45,YO:致死的らしい
  • 47,XXY:Klinefelter症候群 (2個以上のXと1個以上のY:48,XXXY, 49,XXXXY, 46,XY/47,XXYモザイク、48,XXYYなどもありうる)
  • 構造的異常
  • 欠失、逆位、転座、挿入、重複、環状染色体、同腕染色体

流産との関係

  • 全妊娠の10-15%は自然流産であり、自然流産の半数以上は染色体異常が原因である。(QB.P-334)
  • 自然流産児の染色体異常頻度は50-70%、新生児における染色体異常頻度は約1%。


chromosomal abnormality」

  [★]

abnormal karyotypechromosomal aberrationchromosomal anomalychromosomal disorderchromosome aberrationchromosome abnormalitycytogenetic aberrationcytogenetic abnormality


chromosome aberration」

  [★]

abnormal karyotypechromosomal aberrationchromosomal abnormalitychromosomal anomalychromosomal disorderchromosome abnormalitycytogenetic aberrationcytogenetic abnormality

chromosome abnormality」

  [★]

abnormal karyotypechromosomal aberrationchromosomal abnormalitychromosomal anomalychromosomal disorderchromosome aberrationcytogenetic aberrationcytogenetic abnormality

cytogenetic abnormality」

  [★]

abnormal karyotypechromosomal aberrationchromosomal abnormalitychromosomal anomalychromosomal disorderchromosome aberrationchromosome abnormalitycytogenetic aberration

aberration」

  [★]

  • n.
  • 正道を外れること/常道を逸すること。逸脱。異常な性行為。(医)迷錯、精神異常。(生)異常型、かわりもの(sport)
aberrant, aberrantly, abnormal, abnormality, abnormally, anomalous, anomalously, anomaly, defect, departure, deviant, deviate, deviation, diverge, escape, extraordinarily, extraordinary, prolapse, unusual, unusually

WordNet   license wordnet

「an optical phenomenon resulting from the failure of a lens or mirror to produce a good image」
distortion, optical aberration

WordNet   license wordnet

「a disorder in one''s mental state」

PrepTutorEJDIC   license prepejdic

「正道からはずれること,非行,異常 / (軽い)精神異常」


chromosomal」

  [★]

  • 染色体の、染色体性の
chromosomallychromosome

WordNet   license wordnet

「of or relating to a chromosome; "chromosomal defect"」




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