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English Journal

Ocular safety of sildenafil citrate when administered chronically for pulmonary arterial hypertension: results from phase III, randomised, double masked, placebo controlled trial and open label extension.

Wirostko BM, Tressler C, Hwang LJ, Burgess G, Laties AM.Author information University of Utah, Moran Eye Center, Salt Lake City, 84132, USA. barbara.wirostko@gmail.comAbstractOBJECTIVE: To assess the ocular effects and safety profile of chronic sildenafil oral dosing in patients with pulmonary arterial hypertension.
BMJ (Clinical research ed.).BMJ.2012 Feb 21;344:e554. doi: 10.1136/bmj.e554.
OBJECTIVE: To assess the ocular effects and safety profile of chronic sildenafil oral dosing in patients with pulmonary arterial hypertension.DESIGN: 12 week, double masked, randomised, placebo controlled, phase III trial with open label extension.SETTING: 53 institutions worldwide.PARTICIPANTS: 277
PMID 22354598

An open-label comparative pilot study of oral voriconazole and itraconazole for long-term treatment of paracoccidioidomycosis.

Queiroz-Telles F, Goldani LZ, Schlamm HT, Goodrich JM, Espinel-Ingroff A, Shikanai-Yasuda MA.Author information Department of Community Health, Hospital de Clinicas de Curitiba Universidade Federal do Paraná, Curitiba, Paraná, Brazil queiroz.telles@uol.com.brAbstractBACKGROUND: In previous studies, itraconazole was revealed to be an effective therapy and was considered to be the gold standard treatment for mild-to-moderate acute and chronic clinical forms of paracoccidioidomycosis. A pilot study was conducted to investigate the efficacy, safety, and tolerability of voriconazole for the long-term treatment of acute or chronic paracoccidioidomycosis, with itraconazole as the control treatment.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.Clin Infect Dis.2007 Dec 1;45(11):1462-9. Epub 2007 Oct 22.
BACKGROUND: In previous studies, itraconazole was revealed to be an effective therapy and was considered to be the gold standard treatment for mild-to-moderate acute and chronic clinical forms of paracoccidioidomycosis. A pilot study was conducted to investigate the efficacy, safety, and tolerabilit
PMID 17990229

A neuropsychotoxicological assessment of workers in a sodium azide production plant.

Miljours S, Braun CM.Author information Hôpital Juif de Réadaptation, Laval, Quebec, Canada.AbstractOBJECTIVE: Despite its known toxicity and extensive current industrial use, the occupational neuropsychotoxicology of sodium azide has not yet been investigated.
International archives of occupational and environmental health.Int Arch Occup Environ Health.2003 Apr;76(3):225-32. Epub 2002 Dec 14.
OBJECTIVE: Despite its known toxicity and extensive current industrial use, the occupational neuropsychotoxicology of sodium azide has not yet been investigated.METHOD: Neuropsychological and psychological tests, a symptom self-report questionnaire and haematological and cardiac measurements were ga
PMID 12690497