出典: meddic


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「the readily stainable substance of a cell nucleus consisting of DNA and RNA and various proteins; during mitotic division it condenses into chromosomes」
chromatin granule

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/07/20 12:10:26」(JST)

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  • Assessing Cell Cycle Independent Function of the CDK Inhibitor p21(CDKN1A) in DNA Repair.
  • Dutto I1, Tillhon M, Prosperi E.
  • Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1336:123-39. doi: 10.1007/978-1-4939-2926-9_11.
  • The cyclin-dependent kinase (CDK) inhibitor p21(CDKN1A) is a small protein that is able to regulate many important cell functions, often independently of its activity of CDK inhibitor. In addition to cell cycle, this protein regulates cell transcription, apoptosis, cell motility, and DNA repair. In
  • PMID 26231713
  • Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites.
  • Engel JA1, Jones AJ1, Avery VM1, Sumanadasa SD1, Ng SS1, Fairlie DP2, Adams TS1, Andrews KT1.
  • International journal for parasitology. Drugs and drug resistance.Int J Parasitol Drugs Drug Resist.2015 Jun 20;5(3):117-26. doi: 10.1016/j.ijpddr.2015.05.004. eCollection 2015.
  • Histone deacetylase (HDAC) enzymes work together with histone acetyltransferases (HATs) to reversibly acetylate both histone and non-histone proteins. As a result, these enzymes are involved in regulating chromatin structure and gene expression as well as other important cellular processes. HDACs ar
  • PMID 26199860
  • Brg1 Controls the Expression of Pax7 to Promote Viability and Proliferation of Mouse Primary Myoblasts.
  • Padilla-Benavides T1, Nasipak BT1, Imbalzano AN1.
  • Journal of cellular physiology.J Cell Physiol.2015 Dec;230(12):2990-2997. doi: 10.1002/jcp.25031.
  • Brg1 (Brahma-related gene 1) is a catalytic component of the evolutionarily conserved mammalian SWI/SNF ATP-dependent chromatin remodeling enzymes that disrupt histone-DNA contacts on the nucleosome. While the requirement for the SWI/SNF enzymes in cell differentiation has been extensively studied,
  • PMID 26036967
  • p53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating With the Notch Transcriptional Complex Via MAML1.
  • Yun J1,2, Espinoza I3,4, Pannuti A5, Romero D3,4, Martinez L3,4, Caskey M4, Stanculescu A6, Bocchetta M2, Rizzo P7, Band V8, Band H8, Kim HM9, Park SK10, Kang KW11, Avantaggiati ML12, Gomez CR13, Golde T14, Osborne B15, Miele L5.
  • Journal of cellular physiology.J Cell Physiol.2015 Dec;230(12):3115-3127. doi: 10.1002/jcp.25052.
  • p53 and Notch-1 play important roles in breast cancer biology. Notch-1 inhibits p53 activity in cervical and breast cancer cells. Conversely, p53 inhibits Notch activity in T-cells but stimulates it in human keratinocytes. Notch co-activator MAML1 binds p53 and functions as a p53 co-activator. We st
  • PMID 26033683



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WordNet   license wordnet

「the part of a cell nucleus that is relatively uncolored by stains or dyes」



WordNet   license wordnet

「(of substance of a cell nucleus) readily colored by stains」