WordNet

a highly vascular membrane in the eye between the retina and the sclera; a dark pigmentation minimizes the scattering of light inside the eye (同)choroid coat

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1. 加齢黄斑変性：臨床像、病因、および診断 age related macular degeneration clinical presentation etiology and diagnosis
2. 加齢黄斑変性：治療および予防 age related macular degeneration treatment and prevention
3. イールズ病 eales disease
4. 網膜静脈閉塞：疫学、臨床症状、および診断 retinal vein occlusion epidemiology clinical manifestations and diagnosis
5. 網膜静脈閉塞：治療 retinal vein occlusion treatment

Klein A, Loewenstein A.
Developments in ophthalmology.Dev Ophthalmol.2016;55:232-45. doi: 10.1159/000431199. Epub 2015 Oct 26.
Bevacizumab (Avastin) is a recombinant humanized monoclonal immunoglobulin antibody that has two antigen-binding domains and blocks all active forms of vascular endothelial growth factor-A. It was originally designed and is still in use as antitumor agent (for colorectal and non-small cell lung canc
PMID 26502311

Shao J, Choudhary MM, Schachat AP.
Developments in ophthalmology.Dev Ophthalmol.2016;55:125-36. doi: 10.1159/000438969. Epub 2015 Oct 26.
Age-related macular degeneration (AMD) is the leading cause of severe vision loss in individuals over the age of 50 years. Choroidal neovascularization (CNV) is the hallmark of 'wet' or 'exudative' AMD, and is responsible for approximately 90% of cases of severe vision loss due to AMD. Vascular endo
PMID 26501146

Optical Coherence Tomography Angiography of Shallow Irregular Pigment Epithelial Detachments In Pachychoroid Spectrum Disease.

Dansingani KK1, Balaratnasingam C2, Klufas MA3, Sarraf D4, Freund KB5.
American journal of ophthalmology.Am J Ophthalmol.2015 Dec;160(6):1243-1254.e2. doi: 10.1016/j.ajo.2015.08.028. Epub 2015 Aug 28.
PURPOSE: To determine the proportion of shallow irregular pigment epithelial detachments in eyes with pachychoroid features that harbor neovascular tissue and to study the morphology of this tissue with optical coherence tomography (OCT) angiography.DESIGN: Prospective consecutive cohort study.METHO
PMID 26319161

Visual outcome of photodynamic therapy for typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy over 5 years of follow-up

MIKI Akiko,HONDA Shigeru,KOJIMA Hiroshi,NISHIZAKI Masaya,NAGAI Tomoko,FUJIHARA Masashi,UENISHI Mamoru,KITA Mihori,KURIMOTO Yasuo,NEGI Akira,Hyogo Macular Disease Study Group
Japanese journal of ophthalmology 57(3), 301-307, 2013-05-01
NAID 10031176286

CLINICAL INVESTIGATION : Visual outcome of photodynamic therapy for typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy over 5 years of follow-up

Miki Akiko,Honda Shigeru,Kojima Hiroshi [他]
Japanese journal of ophthalmology : the official English-language journal of the Japanese Ophthalmological Society 57(3), 301-307, 2013-05
NAID 40019651410

Specific inhibition of serine/arginine-rich protein kinase attenuates choroidal neovascularization.

Dong Zhenyu,Noda Kousuke,Kanda Atsuhiro,Fukuhara Junichi,Ando Ryo,Murata Miyuki,Saito Wataru,Hagiwara Masatoshi,Ishida Susumu
Molecular vision 19, 536-543, 2013-03-05
… Purpose: To investigate the applicability of serine/arginine-rich protein kinase (SRPK)-specific inhibitor, SRPIN340, for attenuation of choroidal neovascularization (CNV) formation using a mouse model.Methods: Laser photocoagulation was performed to induce CNV in C57BL/6J mice, followed by intravitreal injection of SRPIN340 or vehicle. … Our data suggest the possibility that SRPIN340 is applicable for neovascular age-related macular degeneration as a novel chemical therapeutics. …
NAID 120005372289