- adj.
- 抗コリンの
- n.
- 関
- anticholinergic、anticholinergic agent、anticholinergic drug、anticholinergics、cholinergic antagonist、cholinolytic drug、muscarinic antagonist
WordNet
- a substance that opposes or blocks the action of acetylcholine (同)anticholinergic_drug
- inhibiting or blocking the action of acetylcholine at a receptor site; "anticholinergic drugs"
English Journal
- Stress-associated cardiovascular reaction masks heart rate dependence on physical load in mice.
- Andreev-Andrievskiy AA1, Popova AS2, Borovik AS3, Dolgov ON4, Tsvirkun DV3, Custaud M5, Vinogradova OL3.
- Physiology & behavior.Physiol Behav.2014 Jun 10;132:1-9. doi: 10.1016/j.physbeh.2014.03.033. Epub 2014 May 5.
- When tested on the treadmill mice do not display a graded increase of heart rate (HR), but rather a sharp shift of cardiovascular indices to high levels at the onset of locomotion. We hypothesized that under test conditions cardiovascular reaction to physical load in mice is masked with stress-assoc
- PMID 24802359
- A new activity of N-cholinolytic drug benzohexonium.
- Khnychenko LK1, Okunevich IV, Losev NA, Sapronov NS, Yakovleva EE.
- Bulletin of experimental biology and medicine.Bull Exp Biol Med.2012 Aug;153(4):487-9.
- We have found that N-cholinolytic drug benzohexonium produces a hypolipidemic effect: it reduces dyslipoproteinemia, fatty infiltration of the liver, and risk of atherosclerotic lesions.
- PMID 22977852
- Sildenafil, a phosphodiesterase type 5 inhibitor, enhances the antidepressant activity of amitriptyline but not desipramine, in the forced swim test in mice.
- Socała K1, Nieoczym D, Wyska E, Poleszak E, Wlaź P.
- Journal of neural transmission (Vienna, Austria : 1996).J Neural Transm.2012 Jun;119(6):645-52. doi: 10.1007/s00702-011-0756-9. Epub 2012 Jan 4.
- The cholinergic theory of depression highlights the involvement of muscarinic acetylcholine receptors in the neurobiology of mood disorders. The present study was designed to investigate the effect of sildenafil, a phosphodiesterase type 5 inhibitor which exhibits cholinomimetic properties, alone an
- PMID 22215207
Japanese Journal
- 新β2アドレナリン作働薬Procaterol hydrochloride(OPC-2009)の一般薬理作用-2-末梢作用について
- 橋本 虎六 [他],新谷 成之,山下 修司,鄭 正聰,高井 正明,筒井 正博,河村 公太郎,大川 直士,桧山 隆司,薮内 洋一
- 日本薬理学雑誌 75(4), 333-364, 1979
- … PRO had no α-adrenolytic, cholinolytic and anti-histaminic effects. …
- NAID 130000759078
- Molecular Orbital Interpretations for Cholinergic Activities of Some Alkyltrialkylammonium Derivatives
- 木村 郁子,森島 績,米沢 貞次郎,木村 正康
- Chemical & pharmaceutical bulletin 22(2), 429-432, 1974-02-25
- … The electronic structures of alkyltrialkylammonium derivatives were studied by the CNDO/2 method, and cholinomimetic and cholinolytic activities of these compounds were discussed. …
- NAID 110003633169
- CORRELATION BETWEEN ELECTROENCEPHALOGRAPHIC (EEG) EFFECTS AND ACETYLCHOLINE CONTENT OF BRAIN AFTER CHOLINOLYTIC HALLUCINOGENS
- Matin M.A.
- The Japanese Journal of Pharmacology 19(4), 515-519, 1969
- … The cholinolytic hallucinogens (atropine and hyoscine) reduce the acetylcholine content of rat brain (1) and certain parts of rabbit brain (2). …
- NAID 130000837187
Related Links
- cholinolytic /cho·li·no·lyt·ic/ (-lit´ik). 1. blocking the action of acetylcholine, or of cholinergic agents. 2. an agent that blocks the action of acetylcholine in cholinergic areas, i.e., organs supplied by parasympathetic nerves, and voluntary muscles.
- Cholinolytic definition, capable of blocking the action of acetylcholine and related compounds. See more.
Related Pictures
★リンクテーブル★
| リンク元 | 「抗コリン薬」「muscarinic antagonist」「anticholinergic」「抗コリン」 |
「抗コリン薬」
- 英
- anticholinergics, anticholinergic, anticholinergic agent, anticholinergic drug anticholinergic drugs, cholinolytic, cholinolytic drug, cholinergic antagonist
- 同
- 抗コリン剤、抗コリン作用薬、コリン作用遮断薬 cholinergic blocking agent
- 関
- ムスカリン性受容体拮抗薬 muscarinic antagonist。副交感神経遮断薬
- 副交感神経ムスカリン受容体拮抗薬であり、副交感神経作用を抑制する。
抗コリン薬の主な作用
- (YN2010 抗コリン薬(神経精神))
- 1. 散瞳作用：眼底検査や虹彩炎治療など
- 2. 膀胱利尿筋弛緩作用：尿路結石症鎮痙
- 3. 腺分泌抑制作用：麻酔前投与
- 4. 胃酸分泌抑制作用：抗胃潰瘍
- 5. 消化管運動抑制作用
- 6. 抗Parkinson作用
- 7. 抗迷走神経作用：徐脈性不整脈の治療
- 8. 農薬解毒作用：有機リン剤、カーバメート剤の解毒
therapeutic uses of muscarinic receptor antagonists
- GOO.195
- 呼吸器：気道分泌抑制。(アトロピンは気道分泌を抑制し、分泌物が乾固しうるが、イプラトロピウム、チオトロピウムはmucociliary clearanceにおける副作用を呈しないので、気道疾患に用いられている)
- 泌尿器：過活動性膀胱、夜尿症、対麻痺における頻尿
- 消化器：抗潰瘍薬(M1受容体選択性のある薬剤。ピレンゼピン、テレンゼピン)。鎮痙薬
「muscarinic antagonist」
- 関
- anticholinergic、anticholinergic agent、anticholinergic drug、anticholinergics、cholinergic antagonist、cholinolytic、cholinolytic drug、muscarinic receptor antagonist
「anticholinergic」
- adj.
- 抗コリンの、抗コリン作用の、抗コリン性の
- n.
- 関
- anticholinergic agent、anticholinergic drug、anticholinergics、cholinergic antagonist、cholinolytic、cholinolytic drug、muscarinic antagonist