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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/02/14 02:12:54」(JST)

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  • A retrospective study on post-operative hearing of middle ear cholesteatoma patients with labyrinthine fistula.
  • Bo Y1, Yang Y1,2, Xiaodong C1, Xi W1, Keyong T1, Yu Z1, Ye W1, Kun L1, Zheng Y1, Yang C1, Jianhua Q1.
  • Acta oto-laryngologica.Acta Otolaryngol.2016 Jan;136(1):8-11. doi: 10.3109/00016489.2015.1087650. Epub 2015 Oct 23.
  • CONCLUSIONS: There is no significant change in bone conduction threshold after operation, so the tympanoplasty can be done to maintain hearing when conditions allow.OBJECTIVE: To study the impact of surgical treatment on hearing of cholesteatoma patients with labyrinthine fistula.METHODS: The clinic
  • PMID 26493192
  • Revision surgery for canal wall down mastoidectomy: intra-operative findings and results.
  • Li S1, Meng J1, Zhang F1, Li X1, Qin Z1.
  • Acta oto-laryngologica.Acta Otolaryngol.2016 Jan;136(1):18-22. doi: 10.3109/00016489.2015.1092170. Epub 2015 Sep 25.
  • CONCLUSION: Canal wall down mastoid surgery following multiple earlier surgical failures can be revised by a well-trained experienced surgeon. A dry and safe ear is obtainable in most patients, and hearing preservation is also possible.OBJECTIVES: To analyze the intra-operative findings in revision
  • PMID 26406779
  • TLR4 drives the pathogenesis of acquired cholesteatoma by promoting local inflammation and bone destruction.
  • Si Y1,2, Chen YB3, Chen SJ1,2, Zheng YQ1,2, Liu X1,2, Liu Y1,2, Jiang HL1,2, Xu G1,2, Li ZH1,2, Huang QH1,2, Xiong H1,2, Zhang ZG1,2.
  • Scientific reports.Sci Rep.2015 Dec 7;5:16683. doi: 10.1038/srep16683.
  • Acquired cholesteatoma is a chronic inflammatory disease characterized by both hyperkeratinized squamous epithelial overgrowth and bone destruction. Toll-like receptor (TLR) activation and subsequent inflammatory cytokine production are closely associated with inflammatory bone disease. However, the
  • PMID 26639190


  • 中耳真珠腫における骨吸収機序
  • 鈴木 秀明,小泉 弘樹,北村 拓朗 [他]
  • 耳鼻咽喉科臨床 107(9), 665-671, 2014-09
  • NAID 40020196089
  • 臨床 軟組織による外耳道後壁削除・再建型鼓室形成術後の真珠腫再形成性再発の検討
  • 田中 康広,吉村 剛,増田 文子 [他]
  • 耳鼻咽喉科臨床 107(2), 103-110, 2014-02
  • NAID 40019962483
  • 中耳真珠腫における骨吸収機序
  • 鈴木 秀明,小泉 弘樹,北村 拓朗,寳地 信介,大淵 豊明,橋田 光一
  • 耳鼻咽喉科臨床 107(9), 665-671, 2014
  • … Since the 1980s, a diversity of cytokines, chemical mediators, and enzymes have been detected in cholesteatoma tissue, and presumed to be candidates that play pivotal roles in bone resorption in cholesteatomas. … However, the presence and participation of osteoclasts still remain unclear in human cholesteatoma lesions. …
  • NAID 130004685606


A cholesteatoma consists of squamous epithelium that is trapped within the skull base and that can erode and destroy important structures within the temporal bone. Its potential for causing central nervous system (CNS ...
An abnormal skin growth in the middle ear behind the eardrum is called cholesteatoma. Repeated infections and/or a tear or pulling inward of the eardrum can allow skin into the middle ear.






pearly tumor
コレステリン腫 cholesteatoma