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「a small hard painless nodule at the site of entry of a pathogen (as syphilis)」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/03/19 09:14:25」(JST)

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  • Antigenic variation of TprK facilitates development of secondary syphilis.
  • Reid TB1, Molini BJ2, Fernandez MC2, Lukehart SA3.
  • Infection and immunity.Infect Immun.2014 Dec;82(12):4959-67. doi: 10.1128/IAI.02236-14. Epub 2014 Sep 15.
  • Although primary syphilis lesions heal spontaneously, the infection is chronic, with subsequent clinical stages. Healing of the primary chancre occurs as antibodies against outer membrane antigens facilitate opsonophagocytosis of the bacteria by activated macrophages. TprK is an outer membrane prote
  • PMID 25225245
  • The great imitator revisited: the spectrum of atypical cutaneous manifestations of secondary syphilis.
  • Balagula Y1, Mattei PL, Wisco OJ, Erdag G, Chien AL.
  • International journal of dermatology.Int J Dermatol.2014 Dec;53(12):1434-41. doi: 10.1111/ijd.12518. Epub 2014 Oct 14.
  • Syphilis is a well-known sexually transmitted infection infamous for its protean cutaneous manifestations. Over the last decade, the rate of infection in the USA has risen, particularly among human immunodeficiency virus (HIV)-infected individuals and certain ethnic groups. Although the primary chan
  • PMID 25312512
  • Primary syphilis of the oropharynx: unusual location of a chancre.
  • Drago F1, Ciccarese G2, Cogorno L1, Tomasini CF3, Cozzani EC1, Riva SF1, Parodi A1.
  • International journal of STD & AIDS.Int J STD AIDS.2014 Sep 4. pii: 0956462414551235. [Epub ahead of print]
  • A 33-year-old man presented with a two-week history of an asymptomatic ulcer of the oropharynx and submandibular lymph nodes swelling. Laboratory examinations resulted normal, but serological tests revealed positivity for rapid plasma reagin, Treponema pallidum haemagglutination assay and anti-T. pa
  • PMID 25193247


  • 舌尖部腫瘤から診断に至った第1期梅毒の1例
  • 症例 血管壁への著明なトレポネーマ浸潤を認めた硬性下疳の1例
  • 膣トリコモナス症を併発した陰部外硬性下疳の1例
  • 西日本皮膚科 = The Nishinihon journal of dermatology 72(1), 40-42, 2010-02-01
  • NAID 10026321997


chan·cre / ˈʃæŋ kər / Show Spelled [shang-ker] Show IPA noun Pathology. the initial lesion of syphilis and certain other infectious diseases, commonly a more or less distinct ulcer or sore with a hard base. Origin: 1595–1605; Middle French ...
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Syphilis Chancre Mouth Chancre of primary perosino chancre inoculation (2) chancre of the right middle finger primary syphilitic chancre of the lip an extragenital facial chancre of the lipChancre




chancre, sore
  • 潰瘍に含まれる概念。性病の潰瘍を指す。




  • 下疳の

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