- 関
- brain metabolism
UpToDate Contents
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English Journal
- Inhibition of protein phosphatase-1 and -2A by ellagitannins: structure-inhibitory potency relationships and influences on cellular systems.
- Kónya Z, Bécsi B, Kiss A, Horváth D, Raics M, Kövér KE, Lontay B, Erdődi F.
- Journal of enzyme inhibition and medicinal chemistry. 2019 Dec;34(1)500-509.
- Several ellagitannins inhibited the activity of protein phosphatase-1 (PP1) and -2 A (PP2A) catalytic subunits (PP1c and PP2Ac) with preferential suppression of PP1c over PP2Ac. The inhibitory potency for PP1c followed the order of tellimagrandin I > mahtabin A > praecoxin B > 1.2-Di-O
- PMID 30696301
- Synthesis and biological evaluation of benzothiazin-4-ones: a possible new class of acetylcholinesterase inhibitors.
- Berwaldt GA, Gouvêa DP, da Silva DS, das Neves AM, Soares MSP, Azambuja JH, Siqueira GM, Spanevello RM, Cunico W.
- Journal of enzyme inhibition and medicinal chemistry. 2019 Dec;34(1)197-203.
- A series of nineteen benzothiazin-4-ones from N-(3-aminopropyl) piperidine, 4-(2-aminoethyl)morpholine or 1-(2-aminoethyl)piperidine, aliphatic or aromatic aldehyde and thiosalicylic acid, were synthesized in good yields by multicomponent one-pot reactions. The solvent was toluene and this efficient
- PMID 30482059
- Computer-aided molecular design of pyrazolotriazines targeting glycogen synthase kinase 3.
- Sciú ML, Sebastián-Pérez V, Martinez-Gonzalez L, Benitez R, Perez DI, Pérez C, Campillo NE, Martinez A, Moyano EL.
- Journal of enzyme inhibition and medicinal chemistry. 2019 Dec;34(1)87-96.
- Numerous studies have highlighted the implications of the glycogen synthase kinase 3 (GSK-3) in several processes associated with Alzheimer's disease (AD). Therefore, GSK-3 has become a crucial therapeutic target for the treatment of this neurodegenerative disorder. Hereby, we report the design and
- PMID 30362380
Japanese Journal
- 古川 哲史,田中 敏博,笹野 哲郎
- 内分泌・糖尿病・代謝内科 = Endocrinology, diabetology & metabolism
- NAID 40021856418
- Metabolic Plasticity of Astrocytes and Aging of the Brain
- Morita Mitsuhiro,Ikeshima-Kataoka Hiroko,Kreft Marko,Vardjan Nina,Zorec Robert,Noda Mami
- International Journal of Molecular Sciences 20(4), 941, 2019-02-02
- … As part of the blood-brain-barrier, astrocytes are ideally positioned between cerebral vasculature and neuronal synapses to mediate nutrient uptake from the systemic circulation. … In addition, astrocytes have a robust enzymatic capacity of glycolysis, glycogenesis and lipid metabolism, managing nutrient support in the brain parenchyma for neuronal consumption. …
- NAID 120006599242
- Partial Identification of Amyloid-β Degrading Activity in Human Serum
- Mikawa Ryuta,Okuno Alato,Yoshimi Tatsuya,Watanabe Atsushi,Maruyama Mitsuo,Takikawa Osamu
- Nagoya Journal of Medical Science 81(1), 55-64, 2019-02
- … The major hallmarks of Alzheimer's disease (AD) are the extracellular accumulation of pathological amyloid beta (Aβ) in the brain parenchyma and Aβ deposition in cerebral blood walls (cerebral amyloid angiopathy; … Therefore, BADA may play an important role in the circulation and metabolism of Aβ in human brain microvessels. …
- NAID 120006583841
Related Links
- Journal of Cerebral Blood Flow & Metabolism stands at the interface between basic and clinical neurovascular research, and features research on experimental, theoretical, and clinical aspects of brain circulation, metabolism and ...
- Welcome to the ISCBFM Website! The International Society of Cerebral Blood Flow and Metabolism (ISCBFM) promotes research in cerebral blood flow, cerebral metabolism, and cerebral function in physiological and ...
★リンクテーブル★
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- 英
- brain metabolism、cerebral metabolism
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- 関
- cerebral metabolism
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- 関
- brain、cerebri、cerebro、cerebrum、encephalic、encephalo、encephalon