WordNet

small region of cytoplasm adjacent to the nucleus; contains the centrioles and serves to organize the microtubules (同)central_body
having or situated at or near a center (同)centrical

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1. ネフロン癆の遺伝学および病因 genetics and pathogenesis of nephronophthisis
2. 常染色体優性多発性嚢胞腎の遺伝学および嚢胞成長のメカニズム genetics of autosomal dominant polycystic kidney disease and mechanisms of cyst growth
3. 小児における腎嚢胞性疾患 renal cystic diseases in children
4. 非プラチナ製剤ベースの癌化学療法の神経学的合併症の概要 overview of neurologic complications of non platinum cancer chemotherapy

Hepatoma cell functions modulated by NEK2 are associated with liver cancer progression.

Wu SM1,2, Lin SL1, Lee KY2,3,4, Chuang HC2,4,5, Feng PH2,4, Cheng WL1, Liao CJ1, Chi HC1, Lin YH1, Tsai CY1, Chen WJ6, Yeh CT7, Lin KH1,7.
International journal of cancer.Int J Cancer.2017 Apr 1;140(7):1581-1596. doi: 10.1002/ijc.30559. Epub 2017 Jan 19.
NEK2 (NIMA-related expressed kinase 2) is a serine/threonine centrosomal kinase that acts as a critical regulator of centrosome structure and function. Aberrant NEK2 activities lead to failure in regulating centrosome duplication. NEK2 overexpression promotes tumorigenesis and is associated with poo
PMID 27925179

Nasa I1, Trinkle-Mulcahy L2, Douglas P3, Chaudhuri S1, Lees-Miller SP3, Lee KS4, Moorhead GB5.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2017 Mar 18;484(4):864-870. doi: 10.1016/j.bbrc.2017.02.004. Epub 2017 Feb 8.
Centrosomal protein of 192 kDa (CEP192) is a scaffolding protein that recruits the mitotic protein kinases Aurora A and PLK1 to the centrosome. Here we demonstrate that CEP192 also recruits the type one protein phosphatase (PP1) via a highly conserved KHVTF docking motif. The threonine of the KHVTF
PMID 28188792

Is Centrosomal Protein 70, a Centrosomal Protein with New Roles in Breast Cancer Dissemination and Metastasis, a Facilitator of Epithelial-Mesenchymal Transition?

Lazo PA1.
The American journal of pathology.Am J Pathol.2017 Mar;187(3):494-497. doi: 10.1016/j.ajpath.2016.12.008. Epub 2017 Jan 19.
This commentary highlights the article by Shi et al that identified centrosomal protein 70 as a key mediator of breast cancer growth and metastasis.Copyright © 2017 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.
PMID 28109768

A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors.

Shinohara Ryota,Thumkeo Dean,Kamijo Hiroshi,Kaneko Naoko,Sawamoto Kazunobu,Watanabe Keisuke,Takebayashi Hirohide,Kiyonari Hiroshi,Ishizaki Toshimasa,Furuyashiki Tomoyuki,Narumiya Shuh
Nature neuroscience, 373-380, 2012-01-15
… Concomitantly, anterograde F-actin movement and F-actin condensation at the rear, which occur during centrosomal and nuclear movement of wild-type cells, respectively, were impaired in mDia-deficient neuroblasts. …
NAID 120003726113

河合忍,出川洋介,日野晶也,Degawa Yosuke,日野晶也,Hino Akiya
神奈川大学理学誌 22, 57-62, 2011
… This pair of primers was designed to specifically amplify centrosomal DNA of starfish. … biloba showed high homology (95% identity)with those obtained from the centrosomal DNA of starfish. … Our results show that plants of the genus Ginkgo have a conserved sequence that is similar to the starfish sperm centrosomal DNA sequence and this unique DNA may exist in gymnosperms. …
NAID 120003442136

Expression of the Centrosomal Colon Cancer Autoantigen Gene during Spermatogenesis in the Maturing Rat Testis

Kamio Takashi,Asano Atsushi,Hosaka Yoshinao Z. [他],KHALID Ahmed Magzoub,YOKOTA Shin-ichi,OHTA Masanori,OHYAMA Kenji,YAMANO Yoshiaki
Bioscience, biotechnology, and biochemistry 74(7), 1466-1469, 2010-07-23
We analyzed the gene and protein expression of serologically defined colon cancer antigen 8. Gene expression was upregulated in the maturing rat testis, and was localized to the spermatocytes. Protein …
NAID 10027557490