中心核
WordNet
- in or near a center or constituting a center; the inner area; "a central position"
- a workplace that serves as a telecommunications facility where lines from telephones can be connected together to permit communication (同)telephone exchange, exchange
- a part of the cell containing DNA and RNA and responsible for growth and reproduction (同)cell_nucleus, karyon
- (astronomy) the center of the head of a comet; consists of small solid particles of ice and frozen gas that vaporizes on approaching the sun to form the coma and tail
- any histologically identifiable mass of neural cell bodies in the brain or spinal cord
- the positively charged dense center of an atom
PrepTutorEJDIC
- 『中心の』,中央の,中心からの / 『主要な』,中心的な(main) / (音声が)中舌音の / 電話交換局(《英》[telephone]exchange)
- 中心,核 / (生物の)細胞核 / 原子核
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/06/30 19:09:33」(JST)
[Wiki en表示]
| Central nucleus of the amygdala |
|
| Identifiers |
| NeuroLex ID |
Central amygdaloid nucleus |
| Anatomical terms of neuroanatomy
[edit on Wikidata]
|
The central nucleus of the amygdala (CeA or aCeN) is a nucleus within the amygdala.[1][2] It "serves as the major output nucleus of the amygdala and participates in receiving and processing pain information."[3]
CeA "connects with brainstem areas that control the expression of innate behaviors and associated physiological responses."[4] CeA has dopaminergic projections.
CeA is responsible for "autonomic components of emotions (e.g., changes in heart rate, blood pressure, and respiration) primarily through output pathways to the lateral hypothalamus and brain stem." The CeA is also responsible for "conscious perception of emotion primarily through the ventral amygdalofugal output pathway to the anterior cingulate cortex, orbitofrontal cortex, and prefrontal cortex."[5]
Contents
- 1 Amygdala subdividisions and outputs
- 2 Research
- 3 See also
- 4 References
Amygdala subdividisions and outputs
Inputs and outputs of the rodent central amygdala
The regions described as amygdala nuclei encompass several structures with distinct connectional and functional characteristics in humans and other animals.[6] Among these nuclei are the basolateral complex, the cortical nucleus, the medial nucleus, and the central nucleus. The basolateral complex can be further subdivided into the lateral, the basal, and the accessory basal nuclei.[7][8]
Coronal section of brain through intermediate mass of third ventricle. Amygdala is shown in purple.
The amygdalofugal pathway (Latin for "fleeing from the amygdala" and commonly distinguished as the ventral amygdalofugal pathway) is one of the three principal pathways by which fibers leave the amygdala. The other main efferent pathways from the amygdala are the stria terminalis and anterior commissure. The anterior commissure also serves to connect the two amygdala.[citation needed]
The ventral amygdalofugal pathway carries output from the central and basolateral nuclei and delivers it to a number of targets; namely, the medial dorsal nucleus of the thalamus, the hypothalamus, the basal forebrain, the brain stem, septal nuclei and nucleus accumbens.[citation needed]
Research
- "psychological stressor induced an increase in both CRH mRNA levels and CRH content in the CEA. Exposure to the psychological stressor also caused a significant increase in CRH mRNA levels with a trend for an increase in CRH content in the dorsolateral subdivision of the bed nucleus of the stria terminalis (BNST) which is anatomically associated with the CEA."[9]
- "oxytocin in the CeA exerts a facilitatory role in the maintenance of hydroelectrolyte balance"[10]
- "the central nucleus of the amygdala (CeA) and its connections with the nigral dopamine system have been reported to modulate cognitive processes dependent substantially on attentional allocation. CeA dopamine function is involved in modulation of disengagement behavior."[11]
- "Opioid mechanisms are involved in the control of water and NaCl intake and opioid receptors (ORs) are present in the central nucleus of the amygdala (CeA)" μ-opioid receptors "in the CeA increases hypertonic sodium intake, whereas antagonizing these sites inhibits hypertonic sodium intake. …μ-ORs in the CeA in a positive regulation of sodium intake."[12]
- CeA "is essential for acquiring and expressing conditional fear after overtraining"[13]
- "glucocorticoids can facilitate CRH mRNA expression in the CEA, a site implicated in anxiety and fear"[14]
See also
- Fear conditioning
- Intercalated cells of the amygdala
References
- ^ Keifer, Orion P.; Hurt, Robert C.; Ressler, Kerry J.; Marvar, Paul J. (1 September 2015). "The Physiology of Fear: Reconceptualizing the Role of the Central Amygdala in Fear Learning". Physiology. 30 (5): 389–401. doi:10.1152/physiol.00058.2014.
- ^ Kalin, Ned H.; Shelton, Steven E.; Davidson, Richard J. (2004). "The Role of the Central Nucleus of the Amygdala in Mediating Fear and Anxiety in the Primate". Journal of Neuroscience. 24 (24): 5506–15. PMID 15201323. doi:10.1523/JNEUROSCI.0292-04.2004.
- ^ Hasanein, Parisa; Mirazi, Naser; Javanmardi, Kazem (2008). "GABAA receptors in the central nucleus of amygdala (CeA) affect on pain modulation". Brain Research. 1241: 36–41. PMID 18838064. doi:10.1016/j.brainres.2008.09.041.
- ^ LeDoux, Joseph E. (2008). "Amygdala". Scholarpedia. 3 (4): 2698. doi:10.4249/scholarpedia.2698.
- ^ Wright, Anthony. "Limbic System: Amygdala". In Byrne, John H. Homeostasis and Higher Brain Function. Neuroscience Online. University of Texas Health Science Center at Houston.
- ^ Bzdok, Danilo; Laird, Angela R.; Zilles, Karl; Fox, Peter T.; Eickhoff, Simon B. (2012). "An investigation of the structural, connectional, and functional subspecialization in the human amygdala". Human Brain Mapping. 34 (12): 3247–66. PMC 4801486 . PMID 22806915. doi:10.1002/hbm.22138.
- ^ Best, Ben (August 28, 2012). "The Amygdala and the Emotions". The Anatomical Basis of Mind. Archived from the original on March 9, 2007. [self-published source?]
- ^ Solano-Castiella, Eugenia; Anwander, Alfred; Lohmann, Gabriele; Weiss, Marcel; Docherty, Carol; Geyer, Stefan; Reimer, Enrico; Friederici, Angela D.; Turner, Robert (2010). "Diffusion tensor imaging segments the human amygdala in vivo". NeuroImage. 49 (4): 2958–65. PMID 19931398. doi:10.1016/j.neuroimage.2009.11.027.
- ^ Makino, Shinya; Shibasaki, Tamotsu; Yamauchi, Naoko; Nishioka, Tatsuya; Mimoto, Tomoko; Wakabayashi, Ichiji; Gold, Philip W; Hashimoto, Kozo (1999). "Psychological stress increased corticotropin-releasing hormone mRNA and content in the central nucleus of the amygdala but not in the hypothalamic paraventricular nucleus in the rat". Brain Research. 850 (1–2): 136–43. PMID 10629757. doi:10.1016/S0006-8993(99)02114-9.
- ^ Margatho, Lisandra Oliveira; Elias, Carol Fuzeti; Elias, Lucila Leico Kagohara; Antunes-Rodrigues, Jose (2013). "Oxytocin in the central amygdaloid nucleus modulates the neuroendocrine responses induced by hypertonic volume expansion in the rat". Journal of Neuroendocrinology. 25 (5): 466–77. PMID 23331859. doi:10.1111/jne.12021.
- ^ Smith, Elizabeth S.; Geissler, Sydney A.; Schallert, Timothy; Lee, Hongjoo J. (2013). "The Role of Central Amygdala Dopamine in Disengagement Behavior". Behavioral Neuroscience. 127 (2): 164–74. PMID 23316710. doi:10.1037/a0031043.
- ^ Yan, Junbao; Li, Jinrong; Yan, Jianqun; Sun, Huiling; Wang, Qian; Chen, Ke; Sun, Bo; Wei, Xiaojing; Song, Lin; Zhao, Xiaolin; Wei, Shuangyu; Han, Ling (2013). "Activation of μ-opioid receptors in the central nucleus of the amygdala induces hypertonic sodium intake". Neuroscience. 233: 28–43. PMID 23270855. doi:10.1016/j.neuroscience.2012.12.026.
- ^ Zimmerman, Joshua M.; Rabinak, Christine A.; McLachlan, Ian G.; Maren, Stephen (2007). "The central nucleus of the amygdala is essential for acquiring and expressing conditional fear after overtraining". Learning & Memory. 14 (9): 634–44. PMC 1994080 . PMID 17848503. doi:10.1101/lm.607207.
- ^ Makino, Shinya; Gold, Phillip W.; Schulkin, Jay (1994). "Corticosterone effects on corticotropin-releasing hormone mRNA in the central nucleus of the amygdala and the parvocellular region of the paraventricular nucleus of the hypothalamus". Brain Research. 640 (1–2): 105–12. PMID 8004437. doi:10.1016/0006-8993(94)91862-7.
UpToDate Contents
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English Journal
- Diminished caudate and superior temporal gyrus responses to effort-based decision making in patients with first-episode major depressive disorder.
- Yang XH1, Huang J2, Lan Y3, Zhu CY3, Liu XQ4, Wang YF5, Cheung EF6, Xie GR7, Chan RC8.
- Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2016 Jan 4;64:52-9. doi: 10.1016/j.pnpbp.2015.07.006. Epub 2015 Jul 18.
- BACKGROUND: Anhedonia, the loss of interest or pleasure in reward processing, is a hallmark feature of major depressive disorder (MDD), but its underlying neurobiological mechanism is largely unknown. The present study aimed to examine the underlying neural mechanism of reward-related decision-makin
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- Forlano PM1,2, Sisneros JA3.
- Advances in experimental medicine and biology.Adv Exp Med Biol.2016;877:439-75. doi: 10.1007/978-3-319-21059-9_19.
- The plainfin midshipman fish (Porichthys notatus) is a well-studied model to understand the neural and endocrine mechanisms underlying vocal-acoustic communication across vertebrates. It is well established that steroid hormones such as estrogen drive seasonal peripheral auditory plasticity in femal
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- What the Toadfish Ear Tells the Toadfish Brain About Sound.
- Edds-Walton PL1,2.
- Advances in experimental medicine and biology.Adv Exp Med Biol.2016;877:197-226. doi: 10.1007/978-3-319-21059-9_10.
- Of the three, paired otolithic endorgans in the ear of teleost fishes, the saccule is the one most often demonstrated to have a major role in encoding frequencies of biologically relevant sounds. The toadfish saccule also encodes sound level and sound source direction in the phase-locked activity co
- PMID 26515316
Japanese Journal
- VEMP 所見異常と治療による回復を認めた中枢神経系脱髄疾患の一症例
- Kamikihito Ameliorates Lipopolysaccharide-Induced Sickness Behavior <i>via</i> Attenuating Neural Activation, but Not Inflammation, in the Hypothalamic Paraventricular Nucleus and Central Nucleus of the Amygdala in Mice
- Central insulin-mediated regulation of hepatic glucose production [Review]
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★リンクテーブル★
[★]
- 英
- centromedian nucleus of thalamus CM
- ラ
- nucleus centromedianus thalami
- 同
- 視床中心内側核、正中中心核 central nucleus
[★]
- 英
- centromedian nucleus, CM, central nucleus
- 関
- 中心正中核、視床
[★]
中心傍核
- 関
- central lateral nucleus、central lateral thalamic nucleus、central medial nucleus、centromedian nucleus、centromedian thalamic nucleus、intralaminar nuclear group、intralaminar thalamic nuclei、paracentral thalamic nucleus、parafascicular nucleus、rostral intralaminar nuclei
[★]
扁桃体中心核
- 関
- CeA
[★]
- 中心の、中心的な、中心性の、中枢的な、中枢性の、中枢の、中枢神経性の
- 関
- center、centrally、centrally acting、centre、centro、centrum、hub、medial、pivotal、pivotally