WordNet

in or near a center or constituting a center; the inner area; "a central position"
a workplace that serves as a telecommunications facility where lines from telephones can be connected together to permit communication (同)telephone exchange, exchange
any medicine used to suppress or relieve coughing

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Mochizuki E1, Shirai T1, Noguchi R1, Mitsui C2, Taniguchi M2, Suda T3.
Respirology case reports.Respirol Case Rep.2015 Mar;3(1):3-5. doi: 10.1002/rcr2.85. Epub 2014 Dec 2.
Tipepidine hibenzate, a central antitussive drug, is widely used in the management of cough and is generally safe and well tolerated. We present here a case of anaphylaxis caused by this drug. When the patient had caught a cold over the previous 10 years, she had received medications, including tipe
PMID 25802739

Endogenous central suppressive mechanisms regulating cough as potential targets for novel antitussive therapies.

Mazzone SB1, McGovern AE2, Farrell MJ3.
Current opinion in pharmacology.Curr Opin Pharmacol.2015 Feb 18;22C:1-8. doi: 10.1016/j.coph.2015.02.002. [Epub ahead of print]
Cough and the accompanying sensation known as the urge-to-cough are complex neurobiological phenomena dependent on sensory and motor neural processing at many levels of the neuraxis. In addition to the excitatory neural circuits that provide the positive drive for inducing cough and the urge-to-coug
PMID 25704497

Central administration of nicotine suppresses tracheobronchial cough in anesthetized cats.

Poliacek I1, Rose MJ2, Pitts TE2, Mortensen A2, Corrie LW2, Davenport PW2, Bolser DC2.
Journal of applied physiology (Bethesda, Md. : 1985).J Appl Physiol (1985).2015 Feb 1;118(3):265-72. doi: 10.1152/japplphysiol.00075.2014. Epub 2014 Dec 4.
We tested the hypothesis that nicotine, which acts peripherally to promote coughing, might inhibit reflex cough at a central site. Nicotine was administered via the vertebral artery [intra-arterial (ia)] to the brain stem circulation and by microinjections into a restricted area of the caudal ventra
PMID 25477349

日本呼吸器外科学会雑誌 = The journal of the Japanese Association for Chest Surgery 23(7), 918-923, 2009-11-15
NAID 10025954051

Neuropsychotoxicity of Abused Drugs : Potential of Dextromethorphan and Novel Neuroprotective Analogs of Dextromethorphan With Improved Safety Profiles in Terms of Abuse and Neuroprotective Effects