cell death

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/01/17 16:10:59」(JST)

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  • Effects of dietary components on cancer of the digestive system.
  • Zanini S1, Marzotto M, Giovinazzo F, Bassi C, Bellavite P.
  • Critical reviews in food science and nutrition.Crit Rev Food Sci Nutr.2015 Nov 10;55(13):1870-85. doi: 10.1080/10408398.2012.732126.
  • Cancer is the second leading cause of death in developed countries and poor diet and physical inactivity are major risk factors in cancer-related deaths. Therefore, interventions to reduce levels of smoking, improve diet, and increase physical activity must become much higher priorities in the gener
  • PMID 24841279
  • Regulation of MDM2 Stability After DNA Damage.
  • Li J1, Kurokawa M1,2.
  • Journal of cellular physiology.J Cell Physiol.2015 Oct;230(10):2318-27. doi: 10.1002/jcp.24994.
  • Cells in our body are constantly exposed to various stresses and threats to their genomic integrity. The tumor suppressor protein p53 plays a critical role in successful defense against these threats by inducing apoptotic cell death or cell cycle arrest. In unstressed conditions, p53 levels and acti
  • PMID 25808808
  • TNFα Post-Translationally Targets ZnT2 to Accumulate Zinc in Lysosomes.
  • Hennigar SR1, Kelleher SL1,2,3,4.
  • Journal of cellular physiology.J Cell Physiol.2015 Oct;230(10):2345-50. doi: 10.1002/jcp.24992.
  • Mammary epithelial cells undergo widespread lysosomal-mediated cell death (LCD) during early mammary gland involution. Recently, we demonstrated that tumor necrosis factor-α (TNFα), a cytokine released during early involution, redistributes the zinc (Zn) transporter ZnT2 to accumulate Zn in lysoso
  • PMID 25808614


  • Kobophenol A Inhibits Sodium Nitroprusside-Induced Cardiac H9c2 Cell Death through Suppressing Activation of JNK and Preserving Mitochondrial Anti-apoptotic Bcl-2 and Mcl-1
  • Lee Sung Ryul,Kwak Jong Hwan,Noh Su Jin [他]
  • Chemical and pharmaceutical bulletin 62(7), 713-718, 2014-07
  • NAID 40020103681
  • Korean Red Ginseng Extract Exhibits Neuroprotective Effects through Inhibition of Apoptotic Cell Death
  • Kim Sunyoung,Lee Youngmoon,Cho Jungsook
  • Biological & pharmaceutical bulletin 37(6), 938-946, 2014-06
  • NAID 40020073540
  • Hemolytic Lectin CEL-III Heptamerizes via a Large Structural Transition from α-Helices to a β-Barrel during the Transmembrane Pore Formation Process
  • Unno Hideaki,Goda Shuichiro,Hatakeyama Tomomitsu
  • Journal of Biological Chemistry 289(18), 12805-12812, 2014-05-02
  • … After binding to the cell surface carbohydrate chains through domains 1 and 2, domain 3 self-associates to form transmembrane pores, leading to cell lysis or death, which resembles other pore-forming toxins of diverse organisms. … After heptamerization, domains 1 and 2 form a flat ring, in which all carbohydrate-binding sites remain bound to cell surface carbohydrate chains, stabilizing the transmembrane β-barrel in a position perpendicular to the plane of the lipid bilayer. …
  • NAID 120005438987


Cell death and differentiation is a monthly research journal focused on the exciting field of programmed cell death and apoptosis. It provides a single accessible source of information for both scientists and clinicians, keeping them up ...
日本Cell Death 学会のホームページへようこそ 日本アポトーシス研究会は平成22年1月に「一般社団法人日本Cell Death学会」となりました。 アポトーシスにとどまらず、広い領域での細胞死に関する研究を推進するすべての研究者にとって基盤 ...


 apoptotic or necrotic cell death.jpgCell Death in Eye FormationCell Death cell death in plants and animal apoptosisProgrammed cell deathCell Death and Differentiation - Figure 1

拡張検索apoptotic cell death」「programmed cell death


  [★] アポトーシス

WordNet   license wordnet

「a type of cell death in which the cell uses specialized cellular machinery to kill itself; a cell suicide mechanism that enables metazoans to control cell number and eliminate cells that threaten the animal''s survival」
programmed cell death, caspase-mediated cell death



cell death


  アポトーシス ネクローシス
形態 濃縮、分断化 溶解
膜の強度 保たれる 失われる
ミトコンドリア 影響を受けない 膨潤、Ca取り込み
クロマチン 偏在化、濃縮 凝集
タンパク質合成阻害 死が阻害されうる
actinomycin D
原因 糖質コルチコイド、ホルモン刺激の低下、過剰な刺激、中程度の毒 強い毒、低酸素、pHの大きな変動
典型例 胸腺←糖質コルチコイド 肝臓←肝毒性物質
細胞の変化 リソソームは変化無し リソソームが破裂する
核の変化 特定の長さに切断 ランダムに切断
最初の徴候 エンドヌクレアーゼの活性化 小疱形成、膨潤

apoptotic cell death」


  • ア・トーシス細胞死

programmed cell death」

  [★] プログラム細胞死



  • n.

WordNet   license wordnet

「the time when something ends; "it was the death of all his plans"; "a dying of old hopes"」
dying, demise

WordNet   license wordnet

「the time at which life ends; continuing until dead; "she stayed until his death"; "a struggle to the last"」

WordNet   license wordnet

「the absence of life or state of being dead; "he seemed more content in death than he had ever been in life"」

WordNet   license wordnet

「the permanent end of all life functions in an organism or part of an organism; "the animal died a painful death"」

WordNet   license wordnet

「the act of killing; "he had two deaths on his conscience"」

WordNet   license wordnet

「the event of dying or departure from life; "her death came as a terrible shock"; "upon your decease the capital will pass to your grandchildren"」
decease, expiry

PrepTutorEJDIC   license prepejdic

「〈U〉〈C〉『死』,死亡;死に方,死にざま / 〈U〉死んだ[ような]状体 / 《the~》(…の)絶滅,破滅《+『of』+『名』》 / 《the~》(…の)死の原因,命取り《+『of』+『名』》 / 《通例『D-』》死神(手に鎌(かマ)を持った黒装束の骸骨(がいこつ)で表される)」


  [★] 細胞

WordNet   license wordnet

「small room in which a monk or nun lives」

WordNet   license wordnet

「a device that delivers an electric current as the result of a chemical reaction」
electric cell

WordNet   license wordnet

「a room where a prisoner is kept」
jail cell, prison cell

WordNet   license wordnet

「(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals」

WordNet   license wordnet

「any small compartment; "the cells of a honeycomb"」

WordNet   license wordnet

「a small unit serving as part of or as the nucleus of a larger political movement」

PrepTutorEJDIC   license prepejdic

「(刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞」



WordNet   license wordnet

「the personification of death; "Death walked the streets of the plague-bound city"」