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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/22 13:54:30」(JST)

Cefozopran (INN) is a fourth-generation cephalosporin.

Spectrum of bacterial susceptibility and resistance

Most of the strains of Stenotrophomonas maltophilia have developed resistance toward cefozopran.^[1]

^ "Cefozopran Susceptibility and Resistance Data" (PDF). Retrieved 23 July 2013.

This systemic antibacterial-related article is a stub. You can help Wikipedia by expanding it.

Fatal Case of Toxic Epidermal Necrolysis Caused by Cefozopran and Associated with Psoriasis.

Sawada Y1, Kabashima-Kubo R, Hino R, Nakamura M.
Acta dermato-venereologica.Acta Derm Venereol.2014 May 6;94(3):341-342. doi: 10.2340/00015555-1704.
Abstract is missing (Short).
PMID 24048229

Uehara Yonekawa A1, Iwasaka S, Nakamura H, Fukata M, Kadowaki M, Uchida Y, Odashiro K, Shimoda S, Shimono N, Akashi K.
Internal medicine (Tokyo, Japan).Intern Med.2014;53(9):1029-32. Epub 2014 May 1.
A 73-year-old woman with breast cancer and metastasis under chemotherapy suffered from fever, pleural effusion and pericardial effusion. Despite the administration of treatment with cefozopran and prednisolone, the patient's fever relapsed. An electrocardiogram identified a new complete atrioventric
PMID 24785898

Effect of meropenem with or without immunoglobulin as second-line therapy for pediatric febrile neutropenia.

Kobayashi R1, Suzuki D, Sano H, Kishimoto K, Yasuda K, Kobayashi K.
Pediatrics international : official journal of the Japan Pediatric Society.Pediatr Int.2013 Dec 24. doi: 10.1111/ped.12279. [Epub ahead of print]
BACKGROUND: Meropenem (MEPM) is widely used for treatment of febrile neutropenia. There have been many reports on MEPM for pediatric febrile neutropenia showing success rates of approximately 50-75%. Although i.v. immunoglobulin (IVIG) is widely used for treatment of infection with antibiotics, ther
PMID 24373032

藏前仁,犬飼ともみ,奥川勝 [他],夏目美恵子,佐藤浩二,杉浦充,伊藤誠,中村不二雄
日本環境感染学会誌 27(3), 220-225, 2012
愛知県西三河地区の市中病院で2008年から2010年までの3年間に分離同定され，抗菌薬感受性検査を実施した緑膿菌1343株を対象に，抗菌薬感受性結果の推移を分析した．その結果，カルバペネム系抗菌薬に対する耐性率はIPM/CSで6.4% vs 3.3% (2008年対2010年のデータを対比，以下同様)，MEPMで2.7% vs 1.4%と低下傾向を示した．同時にCPFXの耐性率も13.4% v …
NAID 130002129042

Rupture of Renal Mycotic Aneurysm that Developed during the Treatment of Streptococcal Infective Endocarditis and Vertebral Osteomyelitis

Uno Kenji,Kasahara Kei,Komatsu Yuko,Konishi Mitsuru,Yoshihmoto Eiichiro,Maeda Koichi,Mikasa Keiichi
Internal Medicine 51(10), 1255-1258, 2012
… A 50-year-old woman received two weeks of cefozopran and two weeks of imipenem for streptococcal endocarditis and vertebral osteomyelitis. …
NAID 130002062443

中西啓,水田邦博,大和谷崇 [他],橋本泰幸,浜田登,峯田周幸
耳鼻咽喉科臨床 104(7), 491-498, 2011-07-01
… Malignant external otitis was diagnosed, and the patient was treated with cefozopran. …
NAID 10029062733

リンク元	「セフォゾプラン」
拡張検索	「cefozopran hydrochloride」

Cefozopran
Systematic (IUPAC) name
	(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)- 2-methoxyiminoacetyl]amino]-3-(imidazo[2,3-f]pyridazin- 4-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylate
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Registry Number	113359-04-9
ATC code	J01DE03
PubChem	CID: 9571080
ChemSpider	7845546
UNII	1LG87K28LW
KEGG	D01052
ChEMBL	CHEMBL1276663
Chemical data
Formula	C19H17N9O5S2
Molecular mass	515.52 g/mol
	SMILES O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(=N\OC)/c3nc(sn3)N)Cn5c4cccn[n+]4cc5)C([O-])=O ;
	InChI InChI=1S/C19H17N9O5S2/c1-33-24-11(14-23-19(20)35-25-14)15(29)22-12-16(30)28-13(18(31)32)9(8-34-17(12)28)7-26-5-6-27-10(26)3-2-4-21-27/h2-6,12,17H,7-8H2,1H3,(H3-,20,22,23,25,29,31,32)/b24-11-/t12-,17-/m1/s1 ; Key:QDUIJCOKQCCXQY-WHJQOFBOSA-N ;
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