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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/08/13 07:36:29」(JST)

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  • His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency of the Metallo-β-Lactamase VIM-7.
  • Leiros HK1, Skagseth S2, Edvardsen KS2, Lorentzen MS2, Bjerga GE2, Leiros I2, Samuelsen O3.
  • Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2014 Aug;58(8):4826-4836. Epub 2014 Jun 9.
  • Metallo-β-lactamases (MBLs) are the causative mechanism for resistance to β-lactams, including carbapenems, in many Gram-negative pathogenic bacteria. One important family of MBLs is the Verona integron-encoded MBLs (VIM). In this study, the importance of residues Asp120, Phe218, and His224 in the
  • PMID 24913158
  • Convulsive Liability of Cefepime and Meropenem in Normal and Corneal Kindled Mice.
  • Tanaka A1, Takechi K2, Watanabe S2, Tanaka M2, Suemaru K3, Araki H2.
  • Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2014 Aug;58(8):4380-4383. Epub 2014 May 19.
  • We have reported significantly higher convulsion prevalence in patients treated with cefepime than in those treated with meropenem. Additionally, cefepime-associated convulsions were found only in patients with brain disorders, not renal failure. Here, we compared the convulsive liability of cefepim
  • PMID 24841261
  • Identifying Critically Ill Patients at Risk for Inappropriate Antibiotic Therapy: A Pilot Study of a Point-of-Care Decision Support Alert*.
  • Micek ST1, Heard KM, Gowan M, Kollef MH.
  • Critical care medicine.Crit Care Med.2014 Aug;42(8):1832-8. doi: 10.1097/CCM.0000000000000337.
  • OBJECTIVE: To develop an automated alert aimed at reducing inappropriate antibiotic therapy of serious healthcare-associated infections.DESIGN: Single-center cohort study from November 2011 to November 2012.SETTING: Barnes-Jewish Hospital (1,250-bed academic hospital).PATIENTS: A total of 3,616 crit
  • PMID 24751497


  • 当院において分離された緑膿菌に対する広域抗菌薬の感受性調査とモンテカルロシミュレーションを用いた最適投与方法の検討
  • 平野 龍一,坂本 勇一,手代森 隆一,赤平 恵美,今 めぐみ,立花 直樹
  • 日本環境感染学会誌 28(4), 235-239, 2013
  • …   当院で検出された緑膿菌の約9割がpiperacillin/tazobactam (PIPC/TAZ)やmeropenem (MEPM)に感受性を示したが,imipenem (IPM)やcefepime (CFPM)に対する感受性は他の2剤と比べ低下していた.緑膿菌感染症例に対する広域抗菌薬の使用状況を調査し,モンテカルロシミュレーションによって最大殺菌効果が得られる投与方法を検討した.MEPMやPIPC/TAZによって最大殺菌効果を得られる投与方法は1日3回以上であり,当院で広く用いられている投 …
  • NAID 130003385524
  • Active Screening of Group B Streptococci with Reduced Penicillin Susceptibility and Altered Serotype Distribution Isolated from Pregnant Women in Kobe, Japan
  • Kimura Kouji,Matsubara Kousaku,Yamamoto Go,Shibayama Keigo,Arakawa Yoshichika
  • Japanese Journal of Infectious Diseases 66(2), 158-160, 2013
  • … All 139 isolates were susceptible to penicillin G, ampicillin, cefotaxime, cefepime, and meropenem; …
  • NAID 130003381661
  • 症例報告 セフェピム塩酸塩投与により周期性あるいは律動性脳波所見を呈した2症例
  • 代田 悠一郎,大友 亮,花島 律子 [他]
  • 臨床神経学 52(5), 356-359, 2012-05
  • NAID 40019325495


Cefepime [CFPM] セフェピム, セフェム系 1. 商品名 先発品 注射用マキシピーム 0.5g/注射用マキシピーム 1g/マキシピーム点滴静注用バッグ1g 【ブリストル・マイヤーズ】 後発品 後発品2件 を表示 セフェピム塩酸塩静注用0.5g ...
Cefepime official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. ... Table 1: Recommended Dosage Schedule for Cefepime Injection in Patients with ...


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