出典: meddic


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「enzyme found in most plant and animal cells that functions as an oxidative catalyst; decomposes hydrogen peroxide into oxygen and water」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/02/22 14:12:51」(JST)

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  • Antidiabetic potential of salvianolic acid B in multiple low-dose streptozotocin-induced diabetes.
  • Raoufi S1, Baluchnejadmojarad T, Roghani M, Ghazanfari T, Khojasteh F, Mansouri M.
  • Pharmaceutical biology.Pharm Biol.2015 Dec;53(12):1803-9. doi: 10.3109/13880209.2015.1008148. Epub 2015 Apr 17.
  • CONTEXT: Salvianolic acids are the most abundant water-soluble compounds extracted from the herb Salvia miltiorrhiza L. (Lamiaceae) with antioxidant and protective effects.OBJECTIVE: This study evaluates the antidiabetic effect of salvianolic acid B (Sal B) in multiple low-dose streptozotocin (MLDS)
  • PMID 25885938
  • Protective effects of Hammada scoparia flavonoid-enriched fraction on liver injury induced by warm ischemia/reperfusion.
  • Saidi SA1, Bourogâa E, Bouaziz A, Mongi S, Chaaben R, Jamoussi K, Mezghani-Jarraya R, van Pelt J, El-Feki A.
  • Pharmaceutical biology.Pharm Biol.2015 Dec;53(12):1810-7. doi: 10.3109/13880209.2015.1010737. Epub 2015 Apr 17.
  • CONTEXT: Hepatic ischemia/reperfusion injury (IRI) is a major cause of liver damage during liver surgery and transplantation. Plants have historically been used in treating liver damage, and Hammada scoparia (Pomel) (Chenopodiaceae) has been reported to possess a broad spectrum of pharmacological an
  • PMID 25885934
  • Rosmarinic acid exerts a neuroprotective effect in the kainate rat model of temporal lobe epilepsy: Underlying mechanisms.
  • Khamse S1, Sadr SS, Roghani M, Hasanzadeh G, Mohammadian M.
  • Pharmaceutical biology.Pharm Biol.2015 Dec;53(12):1818-25. doi: 10.3109/13880209.2015.1010738. Epub 2015 Apr 15.
  • CONTEXT: Temporal lobe epilepsy (TLE) is an intractable neurological disorder. Rosmarinic acid (RA) is a natural polyphenol with antioxidant, anti-apoptotic, and anti-inflammatory properties.OBJECTIVE: This study evaluates beneficial effect of RA in intrahippocampal kainate-induced model of TLE.MATE
  • PMID 25874386


  • Comparative Study on the Inhibitory Effects of α-Tocopherol and Radon on Carbon Tetrachloride-Induced Renal Damage
  • Kataoka Takahiro,Yamato Keiko,Nishiyama Yuichi,Morii Yuji,Etani Reo,Takata Yuji,Hanamoto Katsumi,Kawabe Atsuishi,Sakoda Akihiro,Ishimori Yuu,Taguchi Takehito,Yamaoka Kiyonori
  • Renal Failure 34(9), 1181-1187, 2012-10
  • … The activities of superoxide dismutase and catalase in kidneys were significantly higher in mice exposed to radon as compared to mice treated with CCl<sub>4</sub> …
  • NAID 120004702446
  • Isolation and Molecular Characterization of Catalase-Negative Staphylococcus aureus from Sputum of a Patient with Aspiration Pneumonia
  • Horiuchi Kazuki,Matsumoto Takehisa,Hidaka Eiko [他]
  • Japanese Journal of Infectious Diseases 65(5), 439-441, 2012-09
  • NAID 40019427942


Catalase, an enzyme that brings about (catalyzes) the reaction by which hydrogen peroxide is decomposed to water and oxygen. Found extensively in organisms that live in the presence of oxygen, catalase prevents the accumulation ...
Different cells build different types of catalase. Many are available for study in the PDB. The catalase that protects our red blood cells, shown on the left from PDB entry 1qqw , is composed of four identical subunits and uses a heme ...


Catalase © ProteinBoxBot @ WikimediaWhat is Catalase? | What is?catalaseCatalase Structure.pngCatalaseCatalase






2H2O2 → 2H2O +O2
  • あらゆる好気的生物に存在し、過酸化水素を分解する。


  • カタラーゼ陽性細菌:サルモネラ菌、黄色ブドウ球菌、大腸菌、緑膿菌、クレブシエラ → 殺菌できない
  • カタラーゼ陰性細菌:肺炎球菌、溶連菌



obligate anaerobe, obligate anaerobes

  • first aid step1 2006 p.137
  • Clostridium, Bacteroides, and Actinomyces.
catalase and/or superoxideを欠く
  • アミノグリコシド系抗菌薬は無効。微生物の細胞内に薬剤が入るためにO2が必要だから