carbon monoxide diffusing capacity of lung

一酸化炭素肺拡散能力

WordNet

1. the amount that can be contained; "the gas tank has a capacity of 12 gallons" (同)content
2. (computer science) the amount of information (in bytes) that can be stored on a disk drive; "the capacity of a hard disk drive is usually expressed in megabytes"
3. a specified function; "he was employed in the capacity of director"; "he should be retained in his present capacity at a higher salary"
4. the maximum production possible; "the plant is working at 80 per cent capacity"
5. tolerance for alcohol; "he had drunk beyond his capacity"
6. the power to learn or retain knowledge; in law, the ability to understand the facts and significance of your behavior (同)mental ability
7. capability to perform or produce; "among his gifts is his capacity for true altruism"; "limited runway capacity"; "a great capacity for growth"
8. an abundant nonmetallic tetravalent element occurring in three allotropic forms: amorphous carbon and graphite and diamond; occurs in all organic compounds (同)C, atomic number 6
9. a copy made with carbon paper (同)carbon_copy
10. either of two saclike respiratory organs in the chest of vertebrates; serves to remove carbon dioxide and provide oxygen to the blood
11. an oxide containing just one atom of oxygen in the molecule

PrepTutorEJDIC

1. 〈U〉《しばしばa capacity》(建物などの)『収容力』,(容器などの)『容量』,『容積』 / 〈U〉《しばしばa capacity》(人の)『能力』,才能;(物の)性能 / 〈C〉(…の)『資格』,地位《+『of』(『as』)+『名』》
2. 《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
3. 『炭素』(化学記号は『C』) / 〈C〉炭素棒 / 〈C〉《時に〈U〉》=carbon paper
4. 《しばしば複数形で》『肺』,肺臓
5. 一酸化物

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 一酸化炭素拡散能 diffusing capacity for carbon monoxide
• 2. 成人における肺機能検査の概要 overview of pulmonary function testing in adults
• 3. 肺症状を伴うHIV感染患者に対するアプローチ approach to the hiv infected patient with pulmonary symptoms
• 4. 肺切除術前評価 preoperative evaluation for lung resection
• 5. 慢性閉塞性肺疾患（COPD）における肺容量減少術 lung volume reduction surgery in copd

English Journal

• Nailfold videocapillaroscopy and serum VEGF levels in scleroderma are associated with internal organ involvement.

• De Santis M1, Ceribelli A1,2, Cavaciocchi F1, Crotti C1, Massarotti M1, Belloli L1,3, Marasini B1, Isailovic N1, Generali E1, Selmi C4,5.
• Auto- immunity highlights.Auto Immun Highlights.2016 Dec;7(1):5. doi: 10.1007/s13317-016-0077-y. Epub 2016 Feb 15.
• PURPOSE: Nailfold videocapillaroscopy (NVC) identifies the microvascular hallmarks of systemic sclerosis (SSc) and vascular endothelial growth factor (VEGF) and may play a pivotal role in the associated vasculopathy. The aim of the present study was to compare NVC alterations with clinical subsets,
• PMID 26878864

• Transfusion of 35-Day Stored RBCs in the Presence of Endotoxemia Does Not Result in Lung Injury in Humans.

• Peters AL1, van Hezel ME, Cortjens B, Tuip-de Boer AM, van Bruggen R, de Korte D, Jonkers RE, Bonta PI, Zeerleder SS, Lutter R, Juffermans NP, Vlaar AP.
• Critical care medicine.Crit Care Med.2016 Jun;44(6):e412-9. doi: 10.1097/CCM.0000000000001614.
• OBJECTIVE: Transfusion-related acute lung injury is the leading cause of transfusion-related mortality. Preclinical studies have shown that aged RBCs can induce transfusion-related acute lung injury in the presence of a "first hit" (e.g., sepsis). Clinical studies, however, show conflicting results
• PMID 26937863

• The utility of pulmonary function testing in predicting outcomes following liver transplantation.

• Kia L1, Cuttica MJ2, Yang A3, Donnan EN4, Whitsett M4, Singhvi A4, Lemmer A4, Levitsky J1,5.
• Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.Liver Transpl.2016 Jun;22(6):805-11. doi: 10.1002/lt.24426.
• Although pulmonary function tests (PFTs) are routinely performed in patients during the evaluation period before liver transplantation (LT), their utility in predicting post-LT mortality and morbidity outcomes is not known. The aim of this study was to determine the impact of obstructive and/or rest
• PMID 26929108

Japanese Journal

• Usefulness of the desaturation-distance ratio from the six-minute walk test for patients with COPD

• International Journal of
• NAID 120006355660

• Pulmonary Intravascular Large B-cell Lymphoma (IVLBCL) Disguised as an Asthma Exacerbation in a Patient with Asthma

• Internal Medicine 56(14), 1885-1891, 2017
• NAID 130005773843

• Analysis of respiratory function and respiratory impedance in elderly patients with fixed airflow obstruction

• Fujita Medical Journal 3(1), 6-11, 2017
• NAID 130005244531

Related Links

• Diffusing capacity - Wikipedia, the free encyclopedia

Lung diseases that reduce D_M and \theta * V_c [edit]. Diseases that alter lung tissue reduce both D_M and \theta * V_c to a variable extent, and so decrease D_ {L_{CO}} . Loss of lung ...

• DLCO - Wikipedia, the free encyclopedia

DLCO or TLCO (Diffusing capacity or Transfer factor of the lung for carbon monoxide,) is the extent to which oxygen passes from the air sacs of the lungs into the blood. Commonly, it refers to the test used to determine this parameter. It was ...

---

★リンクテーブル★

リンク元	「一酸化炭素肺拡散能力」
関連記事	「capacity」「carbon」「monoxide」

「一酸化炭素肺拡散能力」

　　[★]

英

carbon monoxide pulmonary diffusing capacity carbon monoxide diffusing capacity of lung DLCO

同

CO拡散能力

関

一酸化炭素トランスファーファクター、拡散能

概念

• 肺胞気から肺毛細血管に至るガス移動効率の指標
• 肺毛細血管内を通過する血液の気層との接触時間は0.75sあれば酸素化に影響はない。この接触時間が短くなる、すなわち血流速度が増加した状態では酸素化が不十分となり拡散能の低下として認められる。血流速度は運動時や、あるいは毛細血管が破壊されたり閉塞したりして血管床が減少した病態で上昇する。(SPU.24)
• 20-30ml/min/Torr(YN.I-27)

方法

• 4種混合ガスを用い、最大呼出後急速に最大吸気位まで吸気し、10秒息止めをした後、急速に最大呼出をしCOガスの吸収量を測定して肺拡散能を検査する。

DLCOを低下せしめるファクター

肺間質、気道、肺血管の異常

• (1) 肺胞から肺毛細血管赤血球内ヘモグロビンに至るまでの拡散距離の増加
• (2) 肺胞・肺毛細血管の有効拡散面積の減少
• (3) 換気、血流、拡散能力の肺内不均等分布

YN.I-27

• 1. ガス交換面積減少：肺切除、肺気腫、無気肺、肺結核
• 2. 肺胞壁の肥厚　　：間質性肺炎(サルコイドーシス、肺水腫)
• 3. 肺毛細血管量減少：肺血栓塞栓症

読み方

DLCO上昇

• 軽度肺うっ血　→　肺血流量の増加により軽度上昇(SPU.354)

DLCO低下

• 肺水腫

呼吸器内科 必修マニュアル

p.86

DLCOの基準

• 高値　　　：予測値の141%以上
• 正常　　　：予測値の76-140%
• 軽度低下　：予測値の61-75%
• 中等度低下：予測値の41-60%
• 高度低下　：予測値の40%以下

解釈

スパイロメトリー	DLCO
閉塞性障害あり	低下	肺気腫
	正常～上昇	気管支喘息
拘束性障害あり	低下	肺線維症、(肺切除後)
	正常	胸郭・胸膜異常、神経筋疾患
正常	低下	早期の間質性肺疾患、肺血管障害、貧血、一酸化炭素中毒
	上昇	高度肥満、多血症、(気管支喘息)、左右心内シャント、軽度の左心不全、肺胞出血

参考

• http://xakimich.hp.infoseek.co.jp/laboratory/node30.html

「capacity」

　　[★]

• n.

• 能力、容量

(呼吸器)volumeの和・差はcapacityと呼ぶ傾向があるみたい

• ex.

• functional residual capacity, FRC

関

ability、capability、capacitance、competence、competent、facility、power

　 　 　 　 　 　 　 　

「carbon」

　　[★]

炭素、カーボン

関

C、carbonic

　 　 　

「monoxide」

　　[★]

• 一酸化物、一酸化の