カルバモイルアスパラギン酸
WordNet
- street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
- any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
- having the characteristics of an acid; "an acid reaction"
PrepTutorEJDIC
- 酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/08/15 05:36:15」(JST)
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Carbamoyl aspartic acid
|
Names |
IUPAC name
2-(Carbamoylamino)butanedioic acid[1]
|
Identifiers |
CAS Number
|
- 923-37-5 Y
- 13184-27-5 S Y
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3D model (JSmol)
|
- Interactive image
- Interactive image
|
3DMet |
B00115 |
Beilstein Reference
|
1726861, 1726860 S |
ChEBI |
|
ChemSpider |
- 273 Y
- 1267120 R Y
- 84022 S Y
|
DrugBank |
|
ECHA InfoCard |
100.011.906 |
EC Number |
213-096-6 |
KEGG |
|
MeSH |
ureidosuccinic+acid |
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InChI
-
InChI=1S/C5H8N2O5/c6-5(12)7-2(4(10)11)1-3(8)9/h2H,1H2,(H,8,9)(H,10,11)(H3,6,7,12) Y
Key: HLKXYZVTANABHZ-UHFFFAOYSA-N Y
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SMILES
-
[nH2]:c(:[o]):[nH]C(Cc(:[o]):[oH])c(:[o]):[oH]
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NC(=O)NC(CC(O)=O)C(O)=O
|
Properties |
Chemical formula
|
C5H8N2O5 |
Molar mass |
176.13 g·mol−1 |
log P |
−0.663 |
Acidity (pKa) |
3.649 |
Basicity (pKb) |
10.348 |
Related compounds |
Related alkanoic acids
|
- 3-Ureidopropionic acid
- beta-Ureidoisobutyric acid
- N-Acetylaspartic acid
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Related compounds
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- Biuret
- Bromisoval
- Carbromal
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references |
|
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Carbamoyl aspartic acid (or ureidosuccinic acid) is a carbamate derivative which serves as an intermediate in pyrimidine biosynthesis.
References
- ^ "ureidosuccinic acid - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 26 March 2005. Identification. Retrieved 27 June 2012.
Nucleotide metabolic intermediates
|
Purine metabolism |
Anabolism |
R5P→IMP: |
- R5P
- PRPP
- PRA
- GAR
- FGAR
- FGAM
- AIR
- CAIR
- SAICAR
- AICAR
- FAICAR
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IMP→AMP: |
|
IMP→GMP: |
|
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Catabolism |
- Hypoxanthine
- Xanthine
- Uric acid
- 5-Hydroxyisourate
|
|
Pyrimidine metabolism |
Anabolism |
- Carbamoyl phosphate
- Carbamoyl aspartic acid
- 4,5-Dihydroorotic acid
- Orotic acid
- Orotidine 5'-monophosphate
- Uridine monophosphate
|
Catabolism |
uracil: |
- Dihydrouracil
- 3-Ureidopropionic acid
- β-Alanine
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thymine: |
- Dihydrothymine
- β-Ureidoisobutyric acid
- 3-Aminoisobutyric acid
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|
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UpToDate Contents
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English Journal
- Regulation of Cell Wall Plasticity by Nucleotide Metabolism in Lactococcus lactis.
- Solopova A1, Formosa-Dague C2, Courtin P3, Furlan S3, Veiga P3, Péchoux C4, Armalyte J3, Sadauskas M3, Kok J1, Hols P2, Dufrêne YF2, Kuipers OP1, Chapot-Chartier MP3, Kulakauskas S5.
- The Journal of biological chemistry.J Biol Chem.2016 May 20;291(21):11323-36. doi: 10.1074/jbc.M116.714303. Epub 2016 Mar 28.
- To ensure optimal cell growth and separation and to adapt to environmental parameters, bacteria have to maintain a balance between cell wall (CW) rigidity and flexibility. This can be achieved by a concerted action of peptidoglycan (PG) hydrolases and PG-synthesizing/modifying enzymes. In a search f
- PMID 27022026
- [Study on Serum Metabolite Profiling in Pi-deficiency Rats Based on LC-MS Technique].
- Jia LQ, Zhen BX, Xu Ying, Yang GL.
- Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban.Zhongguo Zhong Xi Yi Jie He Za Zhi.2016 Mar;36(3):359-65.
- OBJECTIVE: To explore metabolite profiling changes in serum of rats with pi-qi deficiency syndrome (PQDS) and pi-yang deficiency syndrome (PYDS) based on liquid chromatograph-mass spectrometer (LC-MS) technique, and to explore the essence of Pi-deficiency syndrome (PDS) from small molecule metabolit
- PMID 27236897
- Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis.
- Rabinovich S1, Adler L1, Yizhak K2, Sarver A1, Silberman A1, Agron S1, Stettner N1, Sun Q3, Brandis A4, Helbling D5, Korman S6, Itzkovitz S7, Dimmock D5, Ulitsky I1, Nagamani SC3,8, Ruppin E2,9,10, Erez A1.
- Nature.Nature.2015 Nov 19;527(7578):379-83. doi: 10.1038/nature15529. Epub 2015 Nov 11.
- Cancer cells hijack and remodel existing metabolic pathways for their benefit. Argininosuccinate synthase (ASS1) is a urea cycle enzyme that is essential in the conversion of nitrogen from ammonia and aspartate to urea. A decrease in nitrogen flux through ASS1 in the liver causes the urea cycle diso
- PMID 26560030
Japanese Journal
- Chromium(III) complexes with amino acids. III. Chromium(III) complexes with acidic, basic and carbamoyl amino acids.
- ,
- Bulletin of the Chemical Society of Japan 50(9), 2288-2291, 1977
- … Syntheses by both the isothermal matrix in a solid state and by the usual solution method have been tried for chromium (III) complexes with L- and DL-asparagine, L- and DL-aspartic acid, L- and DL-glutamine, L- and DL-glutamic acid, L- and DL-lysine, and L-ornithine. …
- NAID 130001970235
- INTERACTION BETWEEN HELIANGINE AND PYRIMIDINES IN ADVENTITIOUS ROOT FORMATION OF PHASEOLUS CUTTINGS
- SHIBAOKA HIROH,ANZAI TADASHI,MITSUHASHI MIEKO,SHIMOKORIYAMA MASAMI
- Plant and cell physiology 8(4), 647-656, 1967-12
- … The promotion was almost completely reversed by 3×10^<-4>M uracil, uridine, cytidine, orotic acid or 6×10^<-4>M carbamoyl DL-aspartic acid, and partly by 3×10^<-4>M thymine or thymidine. … M carbamoyl phosphate and 3×10^<-4>M L-aspartic acid reduced the promotion by heliangine. …
- NAID 110003721827
★リンクテーブル★
[★]
- 英
- carbamoyl aspartic acid
- 同
- N-カルバモイルアスパラギン酸、ウレイドコハク酸 ureidosuccinic acid
[★]
- 関
- Asp、aspartate、aspartic acid、D