cancer suppressor gene

出典: meddic

anti-oncogeneantioncogenegrowth suppressor genemetastasis suppressor generecessive oncogenetumor suppressor gene

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英文文献

  • Spindle microtubule dysfunction and cancer predisposition.
  • Stumpff J1, Ghule PN, Shimamura A, Stein JL, Greenblatt M.
  • Journal of cellular physiology.J Cell Physiol.2014 Dec;229(12):1881-3. doi: 10.1002/jcp.24691.
  • Chromosome segregation and spindle microtubule dynamics are strictly coordinated during cell division in order to preserve genomic integrity. Alterations in the genome that affect microtubule stability and spindle assembly during mitosis may contribute to genomic instability and cancer predispositio
  • PMID 24905602
  • A p53-Dependent Tumor Suppressor Network Is Induced by Selective miR-125a-5p Inhibition in Multiple Myeloma Cells.
  • Leotta M1, Biamonte L, Raimondi L, Ronchetti D, Di Martino MT, Botta C, Leone E, Pitari MR, Neri A, Giordano A, Tagliaferri P, Tassone P, Amodio N.
  • Journal of cellular physiology.J Cell Physiol.2014 Dec;229(12):2106-16. doi: 10.1002/jcp.24669.
  • The analysis of deregulated microRNAs (miRNAs) is emerging as a novel approach to disclose the regulation of tumor suppressor or tumor promoting pathways in tumor cells. Targeting aberrantly expressed miRNAs is therefore a promising strategy for cancer treatment. By miRNA profiling of primary plasma
  • PMID 24819167
  • RUNX3 Facilitates Growth of Ewing Sarcoma Cells.
  • Bledsoe KL1, McGee-Lawrence ME, Camilleri ET, Wang X, Riester SM, van Wijnen AJ, Oliveira AM, Westendorf JJ.
  • Journal of cellular physiology.J Cell Physiol.2014 Dec;229(12):2049-56. doi: 10.1002/jcp.24663.
  • Ewing sarcoma is an aggressive pediatric small round cell tumor that predominantly occurs in bone. Approximately 85% of Ewing sarcomas harbor the EWS/FLI fusion protein, which arises from a chromosomal translocation, t(11:22)(q24:q12). EWS/FLI interacts with numerous lineage-essential transcription
  • PMID 24812032

和文文献

  • Early-onset, severe, and recurrent primary hyperparathyroidism associated with a novel CDC73 mutation
  • , , , , ,
  • Endocrine Journal advpub(0), 2015
  • … Early diagnosis of this syndrome is essential because it is associated with increased risk of parathyroid cancer. … c.271C>T) in exon 3 of the causative gene, CDC73, which encodes the tumor suppressor protein parafibromin. …
  • NAID 130005066950
  • Carbon-Ion Beam Irradiation Kills X-Ray-Resistant p53-Null Cancer Cells by Inducing Mitotic Catastrophe
  • Amornwichet Napapat,Oike Takahiro,Shibata Atsushi,Ogiwara Hideaki,Tsuchiya Naoto,Yamauchi Motohiro,Saitoh Yuka,Sekine Ryota,Isono Mayu,Yoshida Yukari,Ohno Tatsuya,Kohno Takashi,Nakano Takashi
  • PLoS ONE 9(12), e115121, 2014-12-22
  • … and Purpose: To understand the mechanisms involved in the strong killing effect of carbon-ion beam irradiation on cancer cells with TP53 tumor suppressor gene deficiencies.Copyright:Materials and Methods: DNA damage responses after carbon-ion beam or X-ray irradiation in isogenic HCT116 colorectal cancer cell lines with and without TP53 (p53+/ + and p53-/-, respectively) were analyzed as follows: cell survival by clonogenic assay, cell death modes by morphologic …
  • NAID 120005527918
  • 前立腺癌におけるマイクロRNA (特集 去勢抵抗性前立腺癌 : 基礎と臨床の最新研究動向) -- (前立腺癌の最新情報)

関連リンク

• Gene duplication: Having extra copies of a gene, which can lead to it making too much of a certain protein Tumor suppressor genes Tumor suppressor genes are normal genes that slow down cell division, repair DNA mistakes, or
Emory Scientists Find New Prostate Cancer Suppressor Gene Mar. 22, 2005 — A gene named ATBF1 may contribute to the development of prostate cancer through acquired mutations and/or loss of expression, according to ...

関連画像

Tumor Suppressor Genes Colon Cancer ClinicRB1 - HomeTumor Suppressor Genes | Oncogenes and U4.4 Mutates genes and Mutagens - Biology tumor suppressor genesTumor suppressor gene. Causes, symptoms


★リンクテーブル★
先読み癌抑制遺伝子
リンク元antioncogene」「がん抑制遺伝子」「growth suppressor gene」「metastasis suppressor gene
関連記事suppress」「suppressor」「Cancer」「cancer」「gene

癌抑制遺伝子」

  [★]

tumor suppressor gene, tumor suppressor genes, suppressor oncogene, anti-oncogene
がん抑制遺伝子腫瘍抑制遺伝子
癌遺伝子



antioncogene」

  [★]

anti-oncogenecancer suppressor genegrowth suppressor genemetastasis suppressor generecessive oncogenetumor suppressor gene

がん抑制遺伝子」

  [★]

tumor suppressor genecancer suppressor geneantioncogene
癌抑制遺伝子腫瘍抑制遺伝子転移抑制遺伝子成長抑制遺伝子劣性癌遺伝子


growth suppressor gene」

  [★]

anti-oncogeneantioncogenecancer suppressor genemetastasis suppressor generecessive oncogenetumor suppressor gene


metastasis suppressor gene」

  [★]

anti-oncogeneantioncogenecancer suppressor genegrowth suppressor generecessive oncogenetumor suppressor gene


suppress」

  [★]

  • v.
abrogateabrogationarrestcurbdepressdepressioninhibitinhibitionrestrainrestraintsubduesuppression

WordNet   license wordnet

「to put down by force or authority; "suppress a nascent uprising"; "stamp down on littering"; "conquer one''s desires"」
stamp down, inhibit, subdue, conquer, curb

WordNet   license wordnet

「reduce the incidence or severity of or stop; "suppress a yawn"; "this drug can suppress the hemorrhage"」

PrepTutorEJDIC   license prepejdic

「〈反乱など〉‘を'『鎮圧する』…,‘の'活動を押える / 〈感情・欲望など〉‘を'『抑制する』,抑える / …‘の'発表を禁止する,伏せる」

WordNet   license wordnet

「put out of one''s consciousness」
repress

suppressor」

  [★]

inhibitory factorrepressor

WordNet   license wordnet

「someone who suppresses; "dictators are suppressors of free speech"」
suppresser

WordNet   license wordnet

「a gene that suppresses the phenotypic expression of another gene (especially of a mutant gene)」
suppresser, suppressor gene, suppresser gene

PrepTutorEJDIC   license prepejdic

「抑圧する人,鎮圧者 / (ラジオ・テレビの)妨害電波(混信)防止装置」

WordNet   license wordnet

「an electrical device for suppressing unwanted currents」
suppresser


Cancer」

  [★]

WordNet   license wordnet

「type genus of the family Cancridae」
genus Cancer

WordNet   license wordnet

「the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22」
Cancer the Crab, Crab

WordNet   license wordnet

「(astrology) a person who is born while the sun is in Cancer」
Crab

WordNet   license wordnet

「a small zodiacal constellation in the northern hemisphere; between Leo and Gemini」


cancer」

  [★]

癌腫
tumor


WordNet   license wordnet

「any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream」
malignant neoplastic disease

PrepTutorEJDIC   license prepejdic

「〈U〉〈C〉『がん』 / 〈U〉〈C〉害悪 / 《Cancer》(星座の)カニ座」


gene」

  [★] 遺伝子

WordNet   license wordnet

「(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"」
cistron, factor

PrepTutorEJDIC   license prepejdic

「遺伝子」




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