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1. 甲状腺機能低下症の臨床症状 clinical manifestations of hypothyroidism
2. 成人における甲状腺機能亢進症の臨床症状の概要 overview of the clinical manifestations of hyperthyroidism in adults
3. 小児および思春期における甲状腺機能亢進症の臨床症状および診断 clinical manifestations and diagnosis of hyperthyroidism in children and adolescents
4. 甲状腺疾患患者の非甲状腺手術 nonthyroid surgery in the patient with thyroid disease

English Journal

Nrf2-regulated phase-II detoxification enzymes and phase-III transporters are induced by thyroid hormone in rat liver.

Cornejo P, Vargas R, Videla LA.SourceFaculty of Medicine, Diego Portales University, Santiago, Chile.
BioFactors (Oxford, England).Biofactors.2013 Mar 29. doi: 10.1002/biof.1094. [Epub ahead of print]
Thyroid hormone (T3 )-induced calorigenesis triggers the hepatic production of reactive oxygen species (ROS) and redox-sensitive nuclear transcription factor erythroid 2-related factor 2 (Nrf2) activation. The aim of this study was to test the hypothesis that in vivo T3 administration upregulates th
PMID 23554160

Thyroid hormone administration induces rat liver Nrf2 activation: suppression by N-acetylcysteine pretreatment.

Romanque P, Cornejo P, Valdés S, Videla LA.SourceMolecular and Clinical Pharmacology Program, Faculty of Medicine, Institute of Biomedical Sciences, University of Chile, Santiago, Chile.
Thyroid : official journal of the American Thyroid Association.Thyroid.2011 Jun;21(6):655-62. doi: 10.1089/thy.2010.0322. Epub 2011 May 12.
BACKGROUND: Oxidative stress associated with 3,3',5-triiodo-l-thyronine (T(3))-induced calorigenesis upregulates the hepatic expression of mediators of cytoprotective mechanisms. The aim of this study was to evaluate the hypothesis that in vivo T(3) administration triggers a redox-mediated transloca
PMID 21563917

Hormetic responses of thyroid hormone calorigenesis in the liver: Association with oxidative stress.

Videla LA.SourceMolecular and Clinical Pharmacology Program, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile. lvidela@med.uchile.cl
IUBMB life.IUBMB Life.2010 Jun;62(6):460-6. doi: 10.1002/iub.345.
Thyroid hormone (L-3,3',5-triiodothyronine, T(3)) exerts calorigenic effects by accelerating mitochondrial O(2) consumption through transcriptional activation of respiratory genes, with consequent increased reactive oxygen species (ROS) production. In the liver, ROS generation occurs at different si
PMID 20503439

Blood Flow to Brown Adipose Tissue and Norepinephrine-Induced Calorigenesis in Physically Trained Rats

平田耕造
The Japanese Journal of Physiology 32(4), 647-653, 1982
… The calorigenesis occurring in brown adipose tissues (BAT) in response to infused norepinephrine [NE: 4μg/(kg·min)] was estimated from the arteriovenous O<SUB>2</SUB> … The contribution of calorigenesis in BAT to the whole body calorigenic response to NE was estimated at 50 % in TR and 36 % in CT rats. …
NAID 130003476949