WordNet

a white metallic element that burns with a brilliant light; the fifth most abundant element in the earths crust; an important component of most plants and animals (同)Ca, atomic number 20
any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis (同)peptidase, proteinase, proteolytic_enzyme
any tropical African shrub of the genus Protea having alternate rigid leaves and dense colorful flower heads resembling cones

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In vitro pharmacological characterization of vorapaxar, a novel platelet thrombin receptor antagonist.

Hawes BE1, Zhai Y1, Hesk D1, Wirth M1, Wei H1, Chintala M1, Seiffert D2.
European journal of pharmacology.Eur J Pharmacol.2015 Sep 5;762:221-8. doi: 10.1016/j.ejphar.2015.05.046. Epub 2015 May 27.
Vorapaxar is a novel protease-activated receptor-1 (PAR1) antagonist recently approved for the reduction of thrombotic cardiovascular events in patients with a history of myocardial infarction or with peripheral arterial disease. The present study provides a comprehensive in vitro pharmacological ch
PMID 26022529

Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A.

Kløverpris S1, Mikkelsen JH1, Pedersen JH1, Jepsen MR1, Laursen LS1, Petersen SV2, Oxvig C3.
The Journal of biological chemistry.J Biol Chem.2015 Sep 4;290(36):21915-24. doi: 10.1074/jbc.M115.650143. Epub 2015 Jul 20.
Stanniocalcin-1 (STC1) is a disulfide-bound homodimeric glycoprotein, first identified as a hypocalcemic hormone important for maintaining calcium homeostasis in teleost fish. STC1 was later found to be widely expressed in mammals, although it is not believed to function in systemic calcium regulati
PMID 26195635

Examining the Neural and Astroglial Protective Effects of Cellular Prion Protein Expression and Cell Death Protease Inhibition in Mouse Cerebrocortical Mixed Cultures.

Wang KK1, Yang Z, Chiu A, Lin F, Rubenstein R.
Molecular neurobiology.Mol Neurobiol.2015 Sep 4. [Epub ahead of print]
Overexpression of cellular prion protein, PrPC, has cytoprotective effects against neuronal injuries. Inhibition of cell death-associated proteases such as necrosis-linked calpain and apoptosis-linked caspase are also neuroprotective. Here, we systematically studied how PrPC expression levels and ce
PMID 26337296

三浦仁,ミウラヒトシ
岩手医科大学歯学雑誌 = Dental journal of Iwate Medical University 37(2), 110-111, 2012-09-18
NAID 120005330074

An On-Demand Metalloprotease from Psychro-Tolerant Exiguobacterium undae Su-1, the Activity and Stability of Which Are Controlled by the Ca²⁺ Concentration

HARADA Junko,TAKAKU Shusaku,WATANABE Kunihiko
Bioscience, biotechnology, and biochemistry 76(5), 986-992, 2012-05-23
… We found that Su-1 protease is superior to commercially available proteases in proteolytic activity in a lower to normal range of temperature (10–50 °C) as well as in rapid inactivation heat-dependently on the Ca2+ concentration. … Biochemical investigations of the purified enzyme and protein structural analysis after gene cloning confirmed that Su-1 protease conserved high identity in its primary sequence with thermophilic proteases of the M4 family. …
NAID 10030753012