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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/02/24 11:18:47」(JST)

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Calcium-sensing receptor in the T lymphocyte enhanced the apoptosis and cytokine secretion in sepsis.

Wu CL1, Wu QY1, Du JJ1, Zeng JY1, Li TT2, Xu CQ3, Sun YH4.
Molecular immunology.Mol Immunol.2015 Feb;63(2):337-42. doi: 10.1016/j.molimm.2014.08.007. Epub 2014 Sep 23.
Calcium-sensing receptor (CaSR) is a member of the G protein-coupled receptor superfamily that existed in lymphocytes and promoted cytokine secretion. Lymphocytes are also involved in sepsis. However, the role of CaSR in lymphocytes in sepsis is unclear. In this study, we want to examine whether the
PMID 25256599

Receptor expression modulates calcium-sensing receptor mediated intracellular Ca2+ mobilization.

Brennan SC1, Mun HC, Leach K, Kuchel PW, Christopoulos A, Conigrave AD.
Endocrinology.Endocrinology.2015 Jan 21:en20141771. [Epub ahead of print]
Calcium-sensing receptors (CaSRs) are class C G-protein-coupled receptors (GPCRs) that respond to physiological activators, including extracellular Ca2+ (Ca2+o) and L-amino acids, as well as the pharmaceutical calcimimetic, cinacalcet. Unlike Ca2+o, which is an orthosteric agonist, L-amino acids and
PMID 25607893

Chemotactic and proangiogenic role of calcium sensing receptor is linked to secretion of multiple cytokines and growth factors in breast cancer MDA-MB-231 cells.

Hernández-Bedolla MA1, Carretero-Ortega J2, Valadez-Sánchez M1, Vázquez-Prado J3, Reyes-Cruz G4.
Biochimica et biophysica acta.Biochim Biophys Acta.2015 Jan;1853(1):166-82. doi: 10.1016/j.bbamcr.2014.10.011. Epub 2014 Oct 22.
Breast cancer metastasis to the bone, potentially facilitated by chemotactic and angiogenic cytokines, contributes to a dramatic osteolytic effect associated with this invasive behavior. Based on the intrinsic ability of calcium sensing receptor (CaSR) to control hormonal secretion and considering i
PMID 25409930