English Journal

Experimental study of the anticancer effect of gemcitabine combined with sirolimus on chemically induced urothelial lesions.

Vasconcelos-Nobrega C, Colaco A, Santos L, Vala H, Palomino LF, Lopes C, Oliveira PA.SourceAgrarian School of Viseu, Polytechnic Institute of Viseu, Portugal.
Anticancer research.Anticancer Res.2011 May;31(5):1637-42.
BACKGROUND: The purpose of this study was to determine the efficacy of a combination of gemcitabine and sirolimus in a mouse model of invasive bladder cancer.MATERIALS AND METHODS: Gemcitabine (50 mg/kg) and sirolimus (1.5 mg/kg) were administered to animals previously exposed to N-butyl-N-4(hydroxy
PMID 21617220

Efficacy of the EGFr inhibitor Iressa on development of chemically-induced urinary bladder cancers: dose dependency and modulation of biomarkers.

Lubet RA, Lu Y, Bode AM, You M, Verney ZM, Steele VE, Townsend R, Juliana MM, Grubbs CJ.SourceDivision of Cancer Prevention, National Cancer Institute, Executive Plaza North, Suite 2110, 6130 Executive Blvd., Bethesda, MD 20852, USA. lubetr@mail.nih.gov
Oncology reports.Oncol Rep.2011 May;25(5):1389-97. doi: 10.3892/or.2011.1200. Epub 2011 Mar 1.
The effects of the EGFr inhibitor Iressa on development of urinary bladder cancers induced by hydroxybutyl(butyl)nitrosamine (OH-BBN) in rats were examined. Iressa treatment (4.5 or 1.5?mg/kg BW/day) beginning one week after the last dose of OH-BBN decreased the occurrence of large (>200?mg) bl
PMID 21369704

Japanese Journal

Inhibition of N-butyl-N-(4-hydroxybutyl) nitrosamine-induced urinary bladder tumor in rats by alpha-difluoromethylornithine

KAWAHARA Masami,MATSUHASHI Tsutomu,YAGISHITA Tsuguo,TAJIMA Masaharu,MATSUSHIMA Masahiro
泌尿器科紀要 33(1), 27-30, 1987-01
マウスにおけるN-Butyl-N-(4-hydroxybutyl) nitrosamine (BBN)膀胱発癌に対するα-Difluoromethylornithine (DFMO)の抑制効果を調べた.8週齢のWistar系雄性ラット50匹に0.05%BBN含有飲料水を,4週間与えた後,2群に分け,1群には0.1%DFMO含有飲料水を,他群には飲料水をそれぞれ自由に与えながら,CE-2固型飼料で, …
NAID 120002159464

村瀬達良,小林収,青田泰博,三矢英輔,越川卓
泌尿器科紀要 29(3), 303-310, 1983-03
BBNラットの膀胱発癌の経時的変化を病理組織学的および発癌した組織のDNA量について経時的変化を調べた.ヒト膀胱癌と比較するために膀胱全摘標本の多発性乳頭状癌と非乳頭状の浸潤癌についての病理組織およびDNA量を比較検討した.BBNの膀胱発癌の過程はヒト乳頭状癌と発育様相が似ており,乳頭状腫瘍の有効なモデルとなるが,非乳頭状浸潤癌のgrowth patternとは著しい違いが見られたMale Fis …
NAID 120002160449

リンク元	「ブチルヒドロキシブチルニトロソアミン」