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of questionable or minimal quality; "borderline grades"; "marginal writing ability" (同)marginal

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1. 前高血圧症 prehypertension
2. 成人における高血圧の初期評価 initial evaluation of the hypertensive adult
3. 小児および思春期年における高血圧の疫学、危険因子、および原因 epidemiology risk factors and etiology of hypertension in children and adolescents
4. 高血圧における左室肥大の定義および病因 definition and pathogenesis of left ventricular hypertrophy in hypertension
5. 高血圧の治療および予防における運動 exercise in the treatment and prevention of hypertension

Mandel EI, Forman JP, Curhan GC, Taylor EN.SourceRenal Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
American journal of hypertension.Am J Hypertens.2013 Dec;26(12):1405-12. doi: 10.1093/ajh/hpt133. Epub 2013 Aug 13.
BACKGROUND: Several biomarkers of metabolic acidosis, including lower plasma bicarbonate, have been associated with prevalent hypertension in cross-sectional studies. We sought to examine prospectively whether lower plasma bicarbonate is associated with incident hypertension.METHODS: We conducted a
PMID 23942654

T-wave axis deviation and left ventricular hypertrophy interaction in diabetes and hypertension.

Assanelli D, Di Castelnuovo A, Rago L, Badilini F, Vinetti G, Gianfagna F, Salvetti M, Zito F, Donati MB, de Gaetano G, Iacoviello L; on behalf of the Moli-sani Project Investigators.SourceDepartment of Sports-Internal Medicine, University of Brescia, Brescia, Italy.
Journal of electrocardiology.J Electrocardiol.2013 November - December;46(6):487-491. doi: 10.1016/j.jelectrocard.2013.08.002. Epub 2013 Sep 6.
Electrocardiographic signs of left ventricular hypertrophy (ECG-LVH) and T-wave axis (TA) deviation are independent predictors of fatal and non fatal events. We assessed the prevalence of ECG-LVH, TA abnormalities and their combination according to the presence or absence of diabetes and/or hyperten
PMID 24011993

Original rat model of high kinetic unilateral pulmonary hypertension surgically induced by combined surgery.

Meng L, Liu X, Zheng Z, Li J, Meng J, Wei Y, Hu S.SourceState Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China; Department of Surgery, National Center for Cardiovascular Disease, Fuwai Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, People's Republic of China.
The Journal of thoracic and cardiovascular surgery.J Thorac Cardiovasc Surg.2013 Nov;146(5):1220-1226.e1. doi: 10.1016/j.jtcvs.2013.01.018. Epub 2013 Feb 8.
OBJECTIVES: The characteristic morphologic lesions observed in the lungs of patients with congenital cardiac anomalies have not been closely modeled in rat shunt-related models, except for the reversible grade 1 changes. The present study reported an original rat model of unilateral pulmonary hypert
PMID 23395098

Borderline Ankle-Brachial Index Value of 0.91–0.99 Is Associated With Endothelial Dysfunction

Kajikawa Masato,Maruhashi Tatsuya,Iwamoto Yumiko,Iwamoto Akimichi,Matsumoto Takeshi,Hidaka Takayuki,Kihara Yasuki,Chayama Kazuaki,Nakashima Ayumu,Goto Chikara,Noma Kensuke,Higashi Yukihito
Circulation Journal 78(7), 1740-1745, 2014
… Background: An ankle-brachial index (ABI) value of 0.91–0.99 is considered borderline and associated with an increased risk of cardiovascular events. … However, there is no information on the relationship between borderline ABI and endothelial function. … Subjects were divided into 3 groups according to ABI (normal group: 1.00–1.40, borderline group: 0.91–0.99, abnormal group: ≤0.90 or >1.40). …
NAID 130004926966

吉藤元,木下秀之
日本臨床免疫学会会誌 37(6), 454-461, 2014
膠原病に合併する肺動脈性肺高血圧症（PAH）は予後不良であり，早期からの治療介入が望まれる．ボーダーラインPAH（平均肺動脈圧21～24 mmHg）は「PAH予備軍」を選別するための概念である．ボーダーラインPAHへの治療介入の是非について議論の余地があるが，原因疾患が強皮症である場合には，予後が特に不良であり，また，強皮症に合併するボーダーラインPAHの42～55％が数年で確定PAHに移行す …
NAID 130004875943

田中泉香,北川眞理子
日本助産学会誌 28(1), 51-59, 2014
目　的　酸化ストレスとは，「生体の酸化反応と抗酸化反応のバランスが崩れ，前者に傾き，生体にとって好ましくない状態」と定義されている。現在，酸化ストレスに関する研究は数多くなされており，周産期においても，妊娠高血圧症候群や妊娠糖尿病との関連などの報告がされている。しかし，妊娠期における酸化ストレス度・抗酸化力の程度がどのような推移を示しているのかが，未だに明らかにされていない。本研究では，妊娠期の2 …
NAID 130004845844